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Woodline Partners Portfolio holdings

AUM $26.4B
1-Year Est. Return 44.85%
This Fund
S&P 500
This Quarter Est. Return
+9.88%
1 Year Est. Return
+44.85%
3 Year Est. Return
+131.23%
5 Year Est. Return
+174.12%
10 Year Est. Return
–
AUM
$25.8B
AUM Growth
+$4.56B
Cap. Flow
+$3.3B
Cap. Flow %
12.77%
Top 10 Hldgs %
19.43%
Holding
1,157
New
287
Increased
424
Reduced
242
Closed
147

Top Buys

Rank Stock Value
1
IVV icon
iShares Core S&P 500 ETF
IVV
+$997M
2
TXN icon
Texas Instruments
TXN
+$215M
3
NVDA icon
NVIDIA
NVDA
+$209M
4
VZ icon
Verizon
VZ
+$208M
5
APH icon
Amphenol
APH
+$143M

Top Sells

Rank Stock Value
1
T icon
AT&T
T
+$200M
2
MRUS
Merus
MRUS
+$158M
3
ALL icon
Allstate
ALL
+$141M
4
CB icon
Chubb
CB
+$115M
5
ARGX icon
argenx
ARGX
+$106M

Sector Composition

Rank Sector Weight
1 Healthcare 24.16%
2 Technology 23.32%
3 Financials 10.75%
4 Consumer Discretionary 10.22%
5 Communication Services 7.07%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
SO icon
351
Southern Company
SO
$107B
$16.4M 0.06%
187,849
+42,465
+29% +$3.88M
SBUX icon
352
Starbucks
SBUX
$120B
$16.3M 0.06%
193,971
+43,743
+29% +$3.69M
MNST icon
353
Monster Beverage
MNST
$92.1B
$16.3M 0.06%
212,069
+193,002
+1,012% +$13.8M
ODD icon
354
ODDITY Tech
ODD
$624M
$16.1M 0.06%
399,791
-1,438
-0.4% -$65K
THS
355
DELISTED
Treehouse Foods
THS
$15.9M 0.06%
+674,985
New +$14.7M
FHI icon
356
Federated Hermes
FHI
$4.72B
$15.9M 0.06%
+305,421
New +$15.5M
APGE icon
357
Apogee Therapeutics
APGE
$10.2B
$15.9M 0.06%
210,466
+153,145
+267% +$9.65M
KYMR icon
358
Kymera Therapeutics
KYMR
$8.75B
$15.8M 0.06%
203,585
-44,415
-18% -$3M
ICE icon
359
Intercontinental Exchange
ICE
$84.1B
$15.8M 0.06%
97,324
+21,671
+29% +$3.39M
IP icon
360
International Paper
IP
$21.5B
$15.7M 0.06%
+399,805
New +$16.4M
ALKS icon
361
Alkermes
ALKS
$8.11B
$15.6M 0.06%
558,567
– –
DUK icon
362
Duke Energy
DUK
$96.6B
$15.6M 0.06%
132,682
+29,910
+29% +$3.65M
CELH icon
363
Celsius Holdings
CELH
$6.08B
$15.5M 0.06%
339,683
-405,169
-54% -$20.4M
MRSH
364
Marsh
MRSH
$92.2B
$15.5M 0.06%
83,626
+18,652
+29% +$3.49M
LAZ icon
365
Lazard
LAZ
$4.22B
$15.3M 0.06%
+314,530
New +$15.7M
TWLO icon
366
Twilio
TWLO
$29.3B
$15.3M 0.06%
+107,325
New +$13.3M
DPZ icon
367
Domino's
DPZ
$11.9B
$15.2M 0.06%
36,521
-205,793
-85% -$85.8M
CRH icon
368
CRH
CRH
$65B
$15.2M 0.06%
121,545
+15,609
+15% +$1.86M
AVDL
369
DELISTED
Avadel Pharmaceuticals
AVDL
$15.1M 0.06%
702,066
-195,020
-22% -$3.79M
CDTX
370
DELISTED
Cidara Therapeutics
CDTX
$14.9M 0.06%
67,500
+27,460
+69% +$4.44M
SNPS icon
371
Synopsys
SNPS
$77.7B
$14.9M 0.06%
31,692
+6,022
+23% +$2.68M
SMH icon
372
VanEck Semiconductor ETF
SMH
$71.8B
$14.7M 0.06%
40,767
+10,888
+36% +$3.82M
CDNS icon
373
Cadence Design Systems
CDNS
$93.2B
$14.5M 0.06%
46,447
+12,090
+35% +$3.95M
DASH icon
374
DoorDash
DASH
$92.9B
$14.5M 0.06%
63,937
-97,416
-60% -$22.9M
CNTA
375
DELISTED
Centessa Pharmaceuticals
CNTA
$14.5M 0.06%
578,251
+470,580
+437% +$11.9M
13 14
15
16 17

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Woodline Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Woodline Partners held 1,157 positions worth $25.8B, up 21% from $21.2B the previous quarter. Its ten largest holdings account for 19% of the portfolio.

Woodline Partners deployed $3.3B of net new capital in Q4 2025, opening 287 new positions and adding to 424 existing holdings. Its largest new stake was iShares Core S&P 500 ETF: 1,467,676 shares worth $1.01B.

By sector, the portfolio is most concentrated in Healthcare at 24% of assets, up from 24% a quarter earlier, followed by Technology and Financials.

On the sell side, the largest reduction was AT&T, an estimated $200M trimmed.

  • Woodline Partners's largest Q4 2025 buy was iShares Core S&P 500 ETF: 1,467,676 shares worth $1.01B.
  • Woodline Partners added most to Texas Instruments in Q4 2025, an estimated $215M increase.
  • Woodline Partners's biggest Q4 2025 reduction was AT&T, cutting an estimated $200M.
  • Woodline Partners fully exited Merus in Q4 2025, selling an estimated $158M.
  • Woodline Partners's ten largest holdings make up 19% of its $25.8B portfolio in Q4 2025.
  • Woodline Partners opened 287 new positions and closed 147 in Q4 2025.
  • Woodline Partners's portfolio value rose 21% quarter-over-quarter to $25.8B.

Based on Woodline Partners's 13F filing for Q4 2025, filed 17 Feb 2026.