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Two Sigma Investments

Two Sigma Investments Portfolio holdings

AUM $124B
1-Year Est. Return 33.93%
This Fund
S&P 500
This Quarter Est. Return
-0.88%
1 Year Est. Return
+33.93%
3 Year Est. Return
+96.56%
5 Year Est. Return
+105.93%
10 Year Est. Return
+538.88%
AUM
$33.9B
AUM Growth
-$12.9B
Cap. Flow
-$11.3B
Cap. Flow %
-33.44%
Top 10 Hldgs %
7.18%
Holding
4,846
New
656
Increased
881
Reduced
976
Closed
2,305

Top Buys

Rank Stock Value
1
CSCO icon
Cisco
CSCO
+$226M
2
JPM icon
JPMorgan Chase
JPM
+$212M
3
TSM icon
TSMC
TSM
+$204M
4
OXY icon
Occidental Petroleum
OXY
+$194M
5
AAPL icon
Apple
AAPL
+$180M

Sector Composition

Rank Sector Weight
1 Technology 18.43%
2 Healthcare 14.66%
3 Industrials 10.19%
4 Consumer Discretionary 10.1%
5 Financials 9.1%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
MNTK icon
2376
Montauk Renewables
MNTK
$243M
$139K ﹤0.01%
+12,426
New +$130K
CGEM icon
2377
Cullinan Oncology
CGEM
$1.18B
$138K ﹤0.01%
13,213
-2,913
-18% -$39.4K
AIOS
2378
AIOS Tech
AIOS
$38.9M
$138K ﹤0.01%
706
+579
+456% +$158K
TANH icon
2379
Tantech Holdings
TANH
$6.18M
$138K ﹤0.01%
+303
New +$713K
GAIA icon
2380
Gaia
GAIA
$48.1M
$135K ﹤0.01%
27,373
-26,494
-49% -$181K
STXS icon
2381
Stereotaxis
STXS
$143M
$134K ﹤0.01%
35,939
-90,063
-71% -$425K
PRTK
2382
DELISTED
Paratek Pharmaceuticals, Inc.
PRTK
$133K ﹤0.01%
44,884
-26,029
-37% -$97.9K
OESX icon
2383
Orion Energy Systems
OESX
$78.3M
$131K ﹤0.01%
4,680
-20,150
-81% -$647K
GRTS
2384
DELISTED
Gritstone bio, Inc. Common Stock
GRTS
$131K ﹤0.01%
+31,753
New +$168K
SHCO
2385
DELISTED
Soho House & Co
SHCO
$130K ﹤0.01%
+16,804
New +$148K
BTTX
2386
DELISTED
Better Therapeutics, Inc. Common Stock
BTTX
$130K ﹤0.01%
65,792
-58,957
-47% -$204K
ASC icon
2387
Ardmore Shipping
ASC
$670M
$129K ﹤0.01%
+28,726
New +$113K
CTOS icon
2388
Custom Truck One Source
CTOS
$2.42B
$128K ﹤0.01%
15,200
-3,800
-20% -$30.7K
VERO
2389
DELISTED
Venus Concept
VERO
$128K ﹤0.01%
544
-761
-58% -$193K
BDSX icon
2390
Biodesix
BDSX
$262M
$125K ﹤0.01%
3,684
+333
+10% +$21.8K
BUR icon
2391
Burford Capital
BUR
$940M
$125K ﹤0.01%
+13,614
New +$130K
DMAC icon
2392
DiaMedica Therapeutics
DMAC
$358M
$125K ﹤0.01%
50,068
-90,789
-64% -$258K
TELA icon
2393
TELA Bio
TELA
$41.6M
$123K ﹤0.01%
10,548
-5,500
-34% -$66.6K
INFU icon
2394
InfuSystem Holdings
INFU
$241M
$122K ﹤0.01%
12,400
+100
+0.8% +$1.28K
PRVB
2395
DELISTED
Provention Bio, Inc. Common Stock
PRVB
$122K ﹤0.01%
+16,600
New +$99.3K
IPHA
2396
Innate Pharma
IPHA
$208M
$121K ﹤0.01%
36,089
-30,966
-46% -$114K
WHLM
2397
DELISTED
Wilhelmina International, Inc
WHLM
$120K ﹤0.01%
25,732
-17,671
-41% -$78.5K
LJPC
2398
DELISTED
La Jolla Pharmaceutical Company
LJPC
$118K ﹤0.01%
27,544
-60,632
-69% -$264K
TRAW icon
2399
Traws Pharma
TRAW
$8.22M
$117K ﹤0.01%
2,545
-169
-6% -$7.83K
CGTX icon
2400
Cognition Therapeutics
CGTX
$94M
$116K ﹤0.01%
42,102
-41,296
-50% -$159K

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Two Sigma Investments's Q1 2022 Portfolio in Review

As of Q1 2022, Two Sigma Investments held 4,846 positions worth $33.9B, down 28% from $46.8B the previous quarter. Its ten largest holdings account for 7.2% of the portfolio.

Two Sigma Investments withdrew a net $11.3B in Q1 2022, closing 2,305 positions and reducing 976 holdings. Its most notable exit was Pfizer, an estimated $271M position sold in full.

By sector, the portfolio is most concentrated in Technology at 18% of assets, up from 17% a quarter earlier, followed by Healthcare and Industrials.

Against the trend, Two Sigma Investments opened a new position in Cisco worth $223M.

  • Two Sigma Investments's largest Q1 2022 buy was Cisco: 4,001,362 shares worth $223M.
  • Two Sigma Investments added most to JPMorgan Chase in Q1 2022, an estimated $212M increase.
  • Two Sigma Investments's biggest Q1 2022 reduction was Coca-Cola, cutting an estimated $225M.
  • Two Sigma Investments fully exited Pfizer in Q1 2022, selling an estimated $271M.
  • Two Sigma Investments's ten largest holdings make up 7.2% of its $33.9B portfolio in Q1 2022.
  • Two Sigma Investments opened 656 new positions and closed 2,305 in Q1 2022.
  • Two Sigma Investments's portfolio value fell 28% quarter-over-quarter to $33.9B.

Based on Two Sigma Investments's 13F filing for Q1 2022, filed 16 May 2022.