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Two Sigma Investments

Two Sigma Investments Portfolio holdings

AUM $124B
1-Year Est. Return 33.93%
This Fund
S&P 500
This Quarter Est. Return
+3.47%
1 Year Est. Return
+33.93%
3 Year Est. Return
+96.56%
5 Year Est. Return
+105.93%
10 Year Est. Return
+538.83%
AUM
$70.9B
AUM Growth
+$3.72B
Cap. Flow
+$541M
Cap. Flow %
0.76%
Top 10 Hldgs %
4.9%
Holding
4,545
New
899
Increased
1,598
Reduced
1,287
Closed
504

Top Buys

Rank Stock Value
1
XLK icon
State Street Technology Select Sector SPDR ETF
XLK
+$395M
2
VNQ icon
Vanguard Real Estate ETF
VNQ
+$321M
3
XLY icon
State Street Consumer Discretionary Select Sector SPDR ETF
XLY
+$318M
4
NOW icon
ServiceNow
NOW
+$272M
5
SCHH icon
Schwab US REIT ETF
SCHH
+$248M

Top Sells

Rank Stock Value
1
XLF icon
State Street Financial Select Sector SPDR ETF
XLF
+$547M
2
XLP icon
State Street Consumer Staples Select Sector SPDR ETF
XLP
+$447M
3
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$377M
4
QUAL icon
iShares MSCI USA Quality Factor ETF
QUAL
+$299M
5
GOOGL icon
Alphabet (Google) Class A
GOOGL
+$269M

Sector Composition

Rank Sector Weight
1 Technology 15.53%
2 Financials 13%
3 Industrials 11.22%
4 Healthcare 10.29%
5 Consumer Discretionary 9.15%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ARGX icon
51
argenx
ARGX
$52B
$217M 0.31%
258,556
-35,604
-12% -$30.5M
BRK.B icon
52
Berkshire Hathaway Class B
BRK.B
$1.11T
$217M 0.31%
432,154
+53,058
+14% +$26.4M
REGN icon
53
Regeneron Pharmaceuticals
REGN
$78.2B
$217M 0.31%
281,151
-188,752
-40% -$128M
MRNA icon
54
Moderna
MRNA
$22B
$217M 0.31%
7,342,096
-187,885
-2% -$5.1M
ON icon
55
ON Semiconductor
ON
$31.3B
$216M 0.31%
3,993,366
+243,615
+6% +$12.5M
PGR icon
56
Progressive
PGR
$122B
$215M 0.3%
946,277
+17,728
+2% +$4M
LRCX icon
57
Lam Research
LRCX
$369B
$215M 0.3%
1,257,457
-269,615
-18% -$41.9M
XBI icon
58
State Street SPDR S&P Biotech ETF
XBI
$9.62B
$215M 0.3%
1,762,600
+1,754,300
+21,136% +$201M
MSCI icon
59
MSCI
MSCI
$41.8B
$214M 0.3%
372,616
+188,574
+102% +$106M
ANET icon
60
Arista Networks
ANET
$233B
$214M 0.3%
1,630,792
+299,267
+22% +$41.2M
AMT icon
61
American Tower
AMT
$80.6B
$214M 0.3%
1,216,424
+411,663
+51% +$74.9M
KMB icon
62
Kimberly-Clark
KMB
$35.7B
$214M 0.3%
2,116,203
+2,050,786
+3,135% +$224M
UNP icon
63
Union Pacific
UNP
$173B
$211M 0.3%
912,198
-116,878
-11% -$26.7M
IONS icon
64
Ionis Pharmaceuticals
IONS
$9.06B
$210M 0.3%
2,658,646
+1,082,703
+69% +$81.5M
NU icon
65
Nu Holdings
NU
$69.8B
$210M 0.3%
12,542,124
-2,882,748
-19% -$46.3M
PG icon
66
Procter & Gamble
PG
$338B
$210M 0.3%
1,463,914
+66,185
+5% +$9.76M
EQIX icon
67
Equinix
EQIX
$102B
$209M 0.29%
272,870
+223,345
+451% +$175M
AME icon
68
Ametek
AME
$55.9B
$207M 0.29%
1,010,471
+332,715
+49% +$64.7M
IYW icon
69
iShares US Technology ETF
IYW
$24.1B
$207M 0.29%
1,038,224
+475,300
+84% +$95.1M
VRSK icon
70
Verisk Analytics
VRSK
$25.1B
$207M 0.29%
924,687
+279,018
+43% +$63M
GDDY icon
71
GoDaddy
GDDY
$11.2B
$206M 0.29%
1,663,619
+32,519
+2% +$4.21M
W icon
72
Wayfair
W
$11.8B
$204M 0.29%
2,036,019
+125,997
+7% +$12.1M
V icon
73
Visa
V
$683B
$201M 0.28%
573,459
-1,575
-0.3% -$537K
AZN icon
74
AstraZeneca
AZN
$245B
$200M 0.28%
1,090,238
+831,390
+321% +$146M
C icon
75
Citigroup
C
$224B
$200M 0.28%
1,717,333
+692,330
+68% +$71.9M
1 2
3
4 5

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Two Sigma Investments's Q4 2025 Portfolio in Review

As of Q4 2025, Two Sigma Investments held 4,545 positions worth $70.9B, up 5.5% from $67.2B the previous quarter. Its ten largest holdings account for 4.9% of the portfolio.

Two Sigma Investments's Q4 2025 filing shows 899 new, 1,598 increased, 1,287 reduced and 504 closed positions. Its largest new stake was Vanguard Real Estate ETF: 3,573,400 shares worth $316M. The largest sale was State Street Financial Select Sector SPDR ETF, an estimated $547M.

By sector, the portfolio is most concentrated in Technology at 16% of assets, down from 16% a quarter earlier, followed by Financials and Industrials.

  • Two Sigma Investments's largest Q4 2025 buy was Vanguard Real Estate ETF: 3,573,400 shares worth $316M.
  • Two Sigma Investments added most to State Street Technology Select Sector SPDR ETF in Q4 2025, an estimated $395M increase.
  • Two Sigma Investments's biggest Q4 2025 reduction was State Street Financial Select Sector SPDR ETF, cutting an estimated $547M.
  • Two Sigma Investments fully exited State Street SPDR Dow Jones Industrial Average ETF Trust in Q4 2025, selling an estimated $240M.
  • Two Sigma Investments's ten largest holdings make up 4.9% of its $70.9B portfolio in Q4 2025.
  • Two Sigma Investments opened 899 new positions and closed 504 in Q4 2025.
  • Two Sigma Investments's portfolio value rose 5.5% quarter-over-quarter to $70.9B.

Based on Two Sigma Investments's 13F filing for Q4 2025, filed 17 Feb 2026.