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Two Sigma Investments

Two Sigma Investments Portfolio holdings

AUM $124B
1-Year Est. Return 33.93%
This Fund
S&P 500
This Quarter Est. Return
-3.07%
1 Year Est. Return
+33.93%
3 Year Est. Return
+96.56%
5 Year Est. Return
+105.93%
10 Year Est. Return
+538.83%
AUM
$46.8B
AUM Growth
+$933M
Cap. Flow
+$2.08B
Cap. Flow %
4.45%
Top 10 Hldgs %
8.13%
Holding
3,617
New
458
Increased
1,225
Reduced
1,321
Closed
453

Top Buys

Rank Stock Value
1
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$510M
2
AVGO icon
Broadcom
AVGO
+$318M
3
MRVL icon
Marvell Technology
MRVL
+$290M
4
CRM icon
Salesforce
CRM
+$263M
5
AMD icon
Advanced Micro Devices
AMD
+$250M

Top Sells

Rank Stock Value
1
LLY icon
Eli Lilly
LLY
+$255M
2
PGR icon
Progressive
PGR
+$244M
3
V icon
Visa
V
+$238M
4
LRCX icon
Lam Research
LRCX
+$201M
5
ELV icon
Elevance Health
ELV
+$190M

Sector Composition

Rank Sector Weight
1 Technology 17.88%
2 Healthcare 13.28%
3 Financials 10.32%
4 Industrials 9.8%
5 Consumer Discretionary 8.58%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
DASH icon
26
DoorDash
DASH
$87.4B
$231M 0.49%
1,261,677
-263,784
-17% -$49.6M
XLV icon
27
State Street Health Care Select Sector SPDR ETF
XLV
$41.8B
$228M 0.49%
1,559,500
-811,857
-34% -$118M
HUM icon
28
Humana
HUM
$45B
$227M 0.48%
856,776
+269,723
+46% +$72.9M
DHR icon
29
Danaher
DHR
$139B
$227M 0.48%
1,105,601
+78,106
+8% +$17.1M
DG icon
30
Dollar General
DG
$28.2B
$225M 0.48%
2,556,870
+202,735
+9% +$15.3M
MSFT icon
31
Microsoft
MSFT
$3.62T
$223M 0.48%
594,754
-6,015
-1% -$2.45M
MA icon
32
Mastercard
MA
$500B
$223M 0.48%
406,423
-17,114
-4% -$9.32M
IT icon
33
Gartner
IT
$10.1B
$220M 0.47%
523,260
+433,733
+484% +$214M
MCK icon
34
McKesson
MCK
$96.8B
$219M 0.47%
325,934
+161,193
+98% +$99.7M
NVO
35
Novo Nordisk
NVO
$208B
$219M 0.47%
3,147,929
+1,303,506
+71% +$108M
IQV icon
36
IQVIA
IQV
$38.4B
$216M 0.46%
1,226,405
+458,426
+60% +$88.9M
CNC icon
37
Centene
CNC
$31.5B
$216M 0.46%
3,556,336
+1,310,825
+58% +$79.2M
MELI icon
38
Mercado Libre
MELI
$96.3B
$215M 0.46%
110,229
+103,276
+1,485% +$205M
ANET icon
39
Arista Networks
ANET
$233B
$214M 0.46%
2,767,058
+2,306,967
+501% +$234M
ICE icon
40
Intercontinental Exchange
ICE
$85.2B
$214M 0.46%
1,239,002
+246,658
+25% +$40.4M
ISRG icon
41
Intuitive Surgical
ISRG
$135B
$204M 0.44%
411,661
+343,351
+503% +$190M
FTNT icon
42
Fortinet
FTNT
$120B
$202M 0.43%
2,098,119
-65,688
-3% -$6.66M
LIN icon
43
Linde
LIN
$222B
$200M 0.43%
429,725
+300,602
+233% +$135M
MRK icon
44
Merck
MRK
$316B
$198M 0.42%
2,200,701
+271,872
+14% +$25.4M
NFLX icon
45
Netflix
NFLX
$305B
$197M 0.42%
2,112,380
-684,390
-24% -$65.1M
WCN
46
Waste Connections
WCN
$42.3B
$196M 0.42%
1,003,328
+30,377
+3% +$5.62M
NOC icon
47
Northrop Grumman
NOC
$77.9B
$192M 0.41%
374,247
-69,416
-16% -$33.1M
NOW icon
48
ServiceNow
NOW
$118B
$190M 0.41%
1,192,175
+1,170,150
+5,313% +$226M
SPYM
49
State Street SPDR Portfolio S&P 500 ETF
SPYM
$164B
$189M 0.4%
2,878,700
-558,900
-16% -$38.7M
META icon
50
Meta Platforms (Facebook)
META
$1.5T
$189M 0.4%
328,386
-77,844
-19% -$50.2M
1
2
3 4 5

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Two Sigma Investments's Q1 2025 Portfolio in Review

As of Q1 2025, Two Sigma Investments held 3,617 positions worth $46.8B, up 2% from $45.9B the previous quarter. Its ten largest holdings account for 8.1% of the portfolio.

Two Sigma Investments deployed $2.08B of net new capital in Q1 2025, opening 458 new positions and adding to 1,225 existing holdings. Its largest new stake was Advanced Micro Devices: 2,246,952 shares worth $231M.

By sector, the portfolio is most concentrated in Technology at 18% of assets, up from 16% a quarter earlier, followed by Healthcare and Financials.

On the sell side, the largest reduction was Eli Lilly, an estimated $255M trimmed.

  • Two Sigma Investments's largest Q1 2025 buy was Advanced Micro Devices: 2,246,952 shares worth $231M.
  • Two Sigma Investments added most to State Street SPDR S&P 500 ETF Trust in Q1 2025, an estimated $510M increase.
  • Two Sigma Investments's biggest Q1 2025 reduction was Eli Lilly, cutting an estimated $255M.
  • Two Sigma Investments fully exited Coinbase in Q1 2025, selling an estimated $45M.
  • Two Sigma Investments's ten largest holdings make up 8.1% of its $46.8B portfolio in Q1 2025.
  • Two Sigma Investments opened 458 new positions and closed 453 in Q1 2025.
  • Two Sigma Investments's portfolio value rose 2% quarter-over-quarter to $46.8B.

Based on Two Sigma Investments's 13F filing for Q1 2025, filed 15 May 2025.