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Two Sigma Investments

Two Sigma Investments Portfolio holdings

AUM $124B
1-Year Est. Return 33.93%
This Fund
S&P 500
This Quarter Est. Return
-3.07%
1 Year Est. Return
+33.93%
3 Year Est. Return
+96.56%
5 Year Est. Return
+105.93%
10 Year Est. Return
+538.88%
AUM
$46.8B
AUM Growth
+$933M
Cap. Flow
+$2.08B
Cap. Flow %
4.45%
Top 10 Hldgs %
8.13%
Holding
3,617
New
458
Increased
1,225
Reduced
1,321
Closed
453

Top Sells

Rank Stock Value
1
LLY icon
Eli Lilly
LLY
+$255M
2
PGR icon
Progressive
PGR
+$244M
3
V icon
Visa
V
+$238M
4
LRCX icon
Lam Research
LRCX
+$201M
5
ELV icon
Elevance Health
ELV
+$190M

Sector Composition

Rank Sector Weight
1 Technology 17.88%
2 Healthcare 13.28%
3 Financials 10.31%
4 Industrials 9.8%
5 Consumer Discretionary 8.58%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
VRCA icon
3001
Verrica Pharmaceuticals
VRCA
$87.3M
$39.2K ﹤0.01%
8,867
-3,977
-31% -$25.7K
GTEC icon
3002
Greenland Technologies Holding
GTEC
$14.3M
$38.5K ﹤0.01%
22,023
-96,578
-81% -$181K
MRIN
3003
DELISTED
Marin Software
MRIN
$37.3K ﹤0.01%
27,605
-5,418
-16% -$9.97K
EJH icon
3004
E-Home Household Service Holdings
EJH
$4M
$36.9K ﹤0.01%
+25
New +$23.7K
BYND icon
3005
Beyond Meat
BYND
$277M
$36.7K ﹤0.01%
12,018
-55,612
-82% -$205K
CGTX icon
3006
Cognition Therapeutics
CGTX
$96.7M
$34.7K ﹤0.01%
82,544
+28,853
+54% +$17K
HYFT
3007
MindWalk Holdings
HYFT
$61.6M
$34.1K ﹤0.01%
+90,582
New +$40.8K
BTMD icon
3008
Biote Corp
BTMD
$44.9M
$34K ﹤0.01%
10,204
-39,093
-79% -$186K
NEGG icon
3009
Newegg Commerce
NEGG
$359M
$32.9K ﹤0.01%
+6,394
New +$51.4K
GGR icon
3010
Gogoro
GGR
$51.2M
$32.4K ﹤0.01%
6,000
-6,109
-50% -$51.6K
ITRM
3011
DELISTED
Iterum Therapeutics
ITRM
$31.1K ﹤0.01%
25,245
MSS icon
3012
Maison Solutions
MSS
$1.11M
$30.9K ﹤0.01%
+599
New +$35.8K
MGIH icon
3013
Millennium Group International
MGIH
$17.2M
$30.8K ﹤0.01%
+21,113
New +$34.6K
BZFD icon
3014
BuzzFeed
BZFD
$96.7M
$29.7K ﹤0.01%
13,950
-132,428
-90% -$316K
CBUS icon
3015
Cibus
CBUS
$138M
$29.1K ﹤0.01%
15,551
-9,023
-37% -$21.1K
ECX icon
3016
ECARX Holdings
ECX
$432M
$28.1K ﹤0.01%
+22,269
New +$47.6K
ADAP
3017
DELISTED
Adaptimmune Therapeutics
ADAP
$26.8K ﹤0.01%
135,947
+59,600
+78% +$30.9K
PEV
3018
DELISTED
Phoenix Motor Inc. Common Stock
PEV
$26.6K ﹤0.01%
76,424
+60,246
+372% +$21.6K
SKYE icon
3019
Skye Bioscience
SKYE
$18.3M
$26.4K ﹤0.01%
+16,607
New +$45.3K
CLRB icon
3020
Cellectar Biosciences
CLRB
$20.5M
$26.2K ﹤0.01%
2,770
+399
+17% +$3.61K
OTLK icon
3021
Outlook Therapeutics
OTLK
$191M
$25.3K ﹤0.01%
20,719
+10,128
+96% +$17.8K
LYRA
3022
DELISTED
LYRA THERAPEUTICS INC
LYRA
$24.4K ﹤0.01%
3,863
-337
-8% -$3.15K
BTOC
3023
Armlogi Holding Corp
BTOC
$13.1M
$24.1K ﹤0.01%
+24,102
New +$68.2K
BMRA icon
3024
Biomerica
BMRA
$4.98M
$24K ﹤0.01%
+5,295
New +$26.2K
MCRB icon
3025
Seres Therapeutics
MCRB
$48.4M
$22.6K ﹤0.01%
1,616
+395
+32% +$6.18K

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Two Sigma Investments's Q1 2025 Portfolio in Review

As of Q1 2025, Two Sigma Investments held 3,617 positions worth $46.8B, up 2% from $45.9B the previous quarter. Its ten largest holdings account for 8.1% of the portfolio.

Two Sigma Investments deployed $2.08B of net new capital in Q1 2025, opening 458 new positions and adding to 1,225 existing holdings. Its largest new stake was Advanced Micro Devices: 2,246,952 shares worth $231M.

By sector, the portfolio is most concentrated in Technology at 18% of assets, up from 16% a quarter earlier, followed by Healthcare and Financials.

On the sell side, the largest reduction was Eli Lilly, an estimated $255M trimmed.

  • Two Sigma Investments's largest Q1 2025 buy was Advanced Micro Devices: 2,246,952 shares worth $231M.
  • Two Sigma Investments added most to State Street SPDR S&P 500 ETF Trust in Q1 2025, an estimated $510M increase.
  • Two Sigma Investments's biggest Q1 2025 reduction was Eli Lilly, cutting an estimated $255M.
  • Two Sigma Investments fully exited Coinbase in Q1 2025, selling an estimated $45M.
  • Two Sigma Investments's ten largest holdings make up 8.1% of its $46.8B portfolio in Q1 2025.
  • Two Sigma Investments opened 458 new positions and closed 453 in Q1 2025.
  • Two Sigma Investments's portfolio value rose 2% quarter-over-quarter to $46.8B.

Based on Two Sigma Investments's 13F filing for Q1 2025, filed 15 May 2025.