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Two Sigma Investments

Two Sigma Investments Portfolio holdings

AUM $124B
1-Year Est. Return 33.93%
This Fund
S&P 500
This Quarter Est. Return
-3.07%
1 Year Est. Return
+33.93%
3 Year Est. Return
+96.56%
5 Year Est. Return
+105.93%
10 Year Est. Return
+538.88%
AUM
$46.8B
AUM Growth
+$933M
Cap. Flow
+$2.08B
Cap. Flow %
4.45%
Top 10 Hldgs %
8.13%
Holding
3,617
New
458
Increased
1,225
Reduced
1,321
Closed
453

Top Sells

Rank Stock Value
1
LLY icon
Eli Lilly
LLY
+$255M
2
PGR icon
Progressive
PGR
+$244M
3
V icon
Visa
V
+$238M
4
LRCX icon
Lam Research
LRCX
+$201M
5
ELV icon
Elevance Health
ELV
+$190M

Sector Composition

Rank Sector Weight
1 Technology 17.88%
2 Healthcare 13.28%
3 Financials 10.31%
4 Industrials 9.8%
5 Consumer Discretionary 8.58%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
INO icon
2876
Inovio Pharmaceuticals
INO
$69M
$118K ﹤0.01%
+72,364
New +$145K
LILAK icon
2877
Liberty Latin America Class C
LILAK
$1.64B
$117K ﹤0.01%
20,800
+5,070
+32% +$30.8K
INDI icon
2878
indie Semiconductor
INDI
$854M
$117K ﹤0.01%
57,368
-38,062
-40% -$132K
OKUR
2879
OnKure Therapeutics
OKUR
$168M
$117K ﹤0.01%
+27,148
New +$153K
AARD
2880
Aardvark Therapeutics
AARD
$173M
$116K ﹤0.01%
+15,424
New +$173K
MURA
2881
DELISTED
Mural Oncology
MURA
$115K ﹤0.01%
91,624
+26,474
+41% +$96.5K
SWIM icon
2882
Latham Group
SWIM
$880M
$114K ﹤0.01%
17,674
-14,804
-46% -$99.6K
PRM icon
2883
Perimeter Solutions
PRM
$5.77B
$113K ﹤0.01%
+11,222
New +$126K
NOTV
2884
DELISTED
Inotiv
NOTV
$112K ﹤0.01%
50,684
-21,005
-29% -$77.1K
CGEM icon
2885
Cullinan Oncology
CGEM
$1.14B
$112K ﹤0.01%
14,796
-27,409
-65% -$263K
CORZ icon
2886
PUT
Core Scientific
CORZ
$6.75B
$110K ﹤0.01%
15,200
NOAH
2887
Noah Holdings
NOAH
$603M
$110K ﹤0.01%
+11,629
New +$127K
BARK icon
2888
BARK
BARK
$101M
$109K ﹤0.01%
3,908
-3,040
-44% -$106K
LSPD icon
2889
Lightspeed Commerce
LSPD
$1.35B
$106K ﹤0.01%
12,077
-352,323
-97% -$4.54M
MBOT icon
2890
Microbot Medical
MBOT
$127M
$103K ﹤0.01%
+68,198
New +$121K
AGIG
2891
Abundia Global Impact Group
AGIG
$36.5M
$102K ﹤0.01%
13,278
+7,696
+138% +$101K
IMA
2892
ImageneBio Inc
IMA
$64.6M
$102K ﹤0.01%
6,619
-1,779
-21% -$30.7K
FLYW icon
2893
Flywire
FLYW
$2.16B
$101K ﹤0.01%
+10,613
New +$167K
EVTL icon
2894
Vertical Aerospace
EVTL
$173M
$101K ﹤0.01%
+29,990
New +$168K
CLAR icon
2895
Clarus
CLAR
$143M
$101K ﹤0.01%
26,819
-23,750
-47% -$107K
TARA icon
2896
Protara Therapeutics
TARA
$232M
$100K ﹤0.01%
23,590
+9,957
+73% +$44.5K
CURI icon
2897
CuriosityStream
CURI
$161M
$100K ﹤0.01%
37,300
-1,197
-3% -$2.91K
ASTL icon
2898
Algoma Steel
ASTL
$431M
$98.7K ﹤0.01%
18,213
-18,387
-50% -$138K
HBIO icon
2899
Harvard Bioscience
HBIO
$29.2M
$98.1K ﹤0.01%
17,333
+13,751
+384% +$176K
ZVIA icon
2900
Zevia
ZVIA
$111M
$97.9K ﹤0.01%
+45,307
New +$148K

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Two Sigma Investments's Q1 2025 Portfolio in Review

As of Q1 2025, Two Sigma Investments held 3,617 positions worth $46.8B, up 2% from $45.9B the previous quarter. Its ten largest holdings account for 8.1% of the portfolio.

Two Sigma Investments deployed $2.08B of net new capital in Q1 2025, opening 458 new positions and adding to 1,225 existing holdings. Its largest new stake was Advanced Micro Devices: 2,246,952 shares worth $231M.

By sector, the portfolio is most concentrated in Technology at 18% of assets, up from 16% a quarter earlier, followed by Healthcare and Financials.

On the sell side, the largest reduction was Eli Lilly, an estimated $255M trimmed.

  • Two Sigma Investments's largest Q1 2025 buy was Advanced Micro Devices: 2,246,952 shares worth $231M.
  • Two Sigma Investments added most to State Street SPDR S&P 500 ETF Trust in Q1 2025, an estimated $510M increase.
  • Two Sigma Investments's biggest Q1 2025 reduction was Eli Lilly, cutting an estimated $255M.
  • Two Sigma Investments fully exited Coinbase in Q1 2025, selling an estimated $45M.
  • Two Sigma Investments's ten largest holdings make up 8.1% of its $46.8B portfolio in Q1 2025.
  • Two Sigma Investments opened 458 new positions and closed 453 in Q1 2025.
  • Two Sigma Investments's portfolio value rose 2% quarter-over-quarter to $46.8B.

Based on Two Sigma Investments's 13F filing for Q1 2025, filed 15 May 2025.