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Two Sigma Investments Portfolio holdings
AUM
$124B
1-Year Est. Return
33.93%
This Fund
S&P 500
This Quarter
Est. Return
-3.07%
1 Year Est. Return
+33.93%
3 Year Est. Return
+96.56%
5 Year Est. Return
+105.93%
10 Year Est. Return
+538.88%
AUM
$46.8B
AUM Growth
+$933M
(+2%)
Cap. Flow
+$2.08B
Cap. Flow
% of AUM
4.45%
Top 10 Holdings %
Top 10 Hldgs %
8.13%
Holding
3,617
New
458
Increased
1,225
Reduced
1,321
Closed
453
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$510M |
| 2 |
Broadcom
AVGO
|
+$318M |
| 3 |
Marvell Technology
MRVL
|
+$290M |
| 4 |
Salesforce
CRM
|
+$263M |
| 5 |
Advanced Micro Devices
AMD
|
+$250M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Eli Lilly
LLY
|
+$255M |
| 2 |
Progressive
PGR
|
+$244M |
| 3 |
Visa
V
|
+$238M |
| 4 |
Lam Research
LRCX
|
+$201M |
| 5 |
Elevance Health
ELV
|
+$190M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 17.88% |
| 2 | Healthcare | 13.28% |
| 3 | Financials | 10.31% |
| 4 | Industrials | 9.8% |
| 5 | Consumer Discretionary | 8.58% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
2851
ARS Pharmaceuticals
SPRY
$612M
| $135K | ﹤0.01% |
10,771
-87,307
| -89% | -$1.05M |
|
2852
Celcuity
CELC
$4.52B
| $135K | ﹤0.01% |
13,378
-38,460
| -74% | -$435K |
|
|
UPB
2853
Upstream Bio Inc
UPB
$395M
| $133K | ﹤0.01% |
+21,789
| New | +$208K |
|
2854
eGain
EGAN
$201M
| $133K | ﹤0.01% |
27,426
-33,106
| -55% | -$187K |
|
|
HLVX
2855
DELISTED
HilleVax
HLVX
| $132K | ﹤0.01% |
90,715
+35,180
| +63% | +$65K |
|
|
PONY
2856
Pony AI Inc
PONY
$3.54B
| $131K | ﹤0.01% |
+14,885
| New | +$212K |
|
2857
CI&T Inc
CINT
$458M
| $131K | ﹤0.01% |
21,973
+3,733
| +20% | +$25.1K |
|
2858
Microvast
MVST
$302M
| $130K | ﹤0.01% |
111,476
+35,328
| +46% | +$61.4K |
|
2859
Epsilon Energy
EPSN
$173M
| $129K | ﹤0.01% |
18,269
-7,556
| -29% | -$49.4K |
|
2860
Myriad Genetics
MYGN
$312M
| $129K | ﹤0.01% |
+14,500
| New | +$174K |
|
2861
Hycroft Mining Holding Corp
HYMC
$2.47B
| $129K | ﹤0.01% |
39,665
+27,259
| +220% | +$70K |
|
|
ONL
2862
Orion Office REIT
ONL
$160M
| $128K | ﹤0.01% |
60,028
-97,197
| -62% | -$339K |
|
|
ARI
2863
Apollo Commercial Real Estate
ARI
$885M
| $127K | ﹤0.01% |
+13,313
| New | +$126K |
|
2864
Lexeo Therapeutics
LXEO
$378M
| $127K | ﹤0.01% |
+36,624
| New | +$162K |
|
2865
Neurogene
NGNE
$712M
| $127K | ﹤0.01% |
10,844
-9,785
| -47% | -$170K |
|
2866
TScan Therapeutics
TCRX
$52M
| $124K | ﹤0.01% |
+90,201
| New | +$195K |
|
|
FBLA
2867
FB Bancorp
FBLA
$251M
| $123K | ﹤0.01% |
+10,961
| New | +$125K |
|
2868
Rezolute
RZLT
$452M
| $123K | ﹤0.01% |
42,531
-16,932
| -28% | -$73.7K |
|
|
SIFY
2869
Sify Technologies
SIFY
$1.14B
| $123K | ﹤0.01% |
28,736
+5,960
| +26% | +$23.8K |
|
2870
Mission Produce
AVO
$1.17B
| $123K | ﹤0.01% |
11,715
-52,402
| -82% | -$611K |
|
|
SION
2871
Sionna Therapeutics
SION
$2.31B
| $123K | ﹤0.01% |
+11,715
| New | +$191K |
|
|
LAND
2872
Gladstone Land Corp
LAND
$360M
| $123K | ﹤0.01% |
+11,646
| New | +$128K |
|
2873
Zura Bio
ZURA
$566M
| $121K | ﹤0.01% |
94,055
-12,571
| -12% | -$19.8K |
|
2874
Inseego
INSG
$90.5M
| $121K | ﹤0.01% |
14,849
-18,102
| -55% | -$198K |
|
2875
Cosan
CSAN
$2.84B
| $118K | ﹤0.01% |
+22,649
| New | +$119K |
|
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Two Sigma Investments's Q1 2025 Portfolio in Review
As of Q1 2025, Two Sigma Investments held 3,617 positions worth $46.8B, up 2% from $45.9B the previous quarter. Its ten largest holdings account for 8.1% of the portfolio.
Two Sigma Investments deployed $2.08B of net new capital in Q1 2025, opening 458 new positions and adding to 1,225 existing holdings. Its largest new stake was Advanced Micro Devices: 2,246,952 shares worth $231M.
By sector, the portfolio is most concentrated in Technology at 18% of assets, up from 16% a quarter earlier, followed by Healthcare and Financials.
On the sell side, the largest reduction was Eli Lilly, an estimated $255M trimmed.
- Two Sigma Investments's largest Q1 2025 buy was Advanced Micro Devices: 2,246,952 shares worth $231M.
- Two Sigma Investments added most to State Street SPDR S&P 500 ETF Trust in Q1 2025, an estimated $510M increase.
- Two Sigma Investments's biggest Q1 2025 reduction was Eli Lilly, cutting an estimated $255M.
- Two Sigma Investments fully exited Coinbase in Q1 2025, selling an estimated $45M.
- Two Sigma Investments's ten largest holdings make up 8.1% of its $46.8B portfolio in Q1 2025.
- Two Sigma Investments opened 458 new positions and closed 453 in Q1 2025.
- Two Sigma Investments's portfolio value rose 2% quarter-over-quarter to $46.8B.
Based on Two Sigma Investments's 13F filing for Q1 2025, filed 15 May 2025.