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Two Sigma Investments

Two Sigma Investments Portfolio holdings

AUM $124B
1-Year Est. Return 33.93%
This Fund
S&P 500
This Quarter Est. Return
-3.07%
1 Year Est. Return
+33.93%
3 Year Est. Return
+96.56%
5 Year Est. Return
+105.93%
10 Year Est. Return
+538.88%
AUM
$46.8B
AUM Growth
+$933M
Cap. Flow
+$2.08B
Cap. Flow %
4.45%
Top 10 Hldgs %
8.13%
Holding
3,617
New
458
Increased
1,225
Reduced
1,321
Closed
453

Top Sells

Rank Stock Value
1
LLY icon
Eli Lilly
LLY
+$255M
2
PGR icon
Progressive
PGR
+$244M
3
V icon
Visa
V
+$238M
4
LRCX icon
Lam Research
LRCX
+$201M
5
ELV icon
Elevance Health
ELV
+$190M

Sector Composition

Rank Sector Weight
1 Technology 17.88%
2 Healthcare 13.28%
3 Financials 10.31%
4 Industrials 9.8%
5 Consumer Discretionary 8.58%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
IVT icon
2726
InvenTrust Properties
IVT
$2.59B
$243K ﹤0.01%
8,289
-63,757
-88% -$1.88M
ACIW icon
2727
ACI Worldwide
ACIW
$5.42B
$241K ﹤0.01%
4,412
+12
+0.3% +$637
LTBR icon
2728
Lightbridge
LTBR
$311M
$241K ﹤0.01%
32,316
-201,418
-86% -$1.79M
CRWV
2729
CoreWeave
CRWV
$49.5B
$241K ﹤0.01%
+6,500
New +$251K
IMTX icon
2730
Immatics
IMTX
$1.32B
$240K ﹤0.01%
53,129
-17,195
-24% -$89.7K
MSGE icon
2731
Madison Square Garden
MSGE
$3.62B
$239K ﹤0.01%
+7,310
New +$255K
INMB icon
2732
INmune Bio
INMB
$57.7M
$239K ﹤0.01%
30,563
-35,821
-54% -$284K
MYPS icon
2733
PLAYSTUDIOS Inc
MYPS
$90.1M
$238K ﹤0.01%
187,519
+1,367
+0.7% +$2.22K
KYTX icon
2734
Kyverna Therapeutics
KYTX
$484M
$237K ﹤0.01%
122,977
-58,677
-32% -$173K
CLFD icon
2735
Clearfield
CLFD
$374M
$237K ﹤0.01%
+7,985
New +$267K
RCKY icon
2736
Rocky Brands
RCKY
$369M
$237K ﹤0.01%
13,653
+565
+4% +$12.3K
CMG icon
2737
Chipotle Mexican Grill
CMG
$41.5B
$237K ﹤0.01%
4,718
-43,249
-90% -$2.35M
OLMA icon
2738
Olema Pharmaceuticals
OLMA
$1.05B
$237K ﹤0.01%
62,926
-9,951
-14% -$50K
STRA icon
2739
Strategic Education
STRA
$1.92B
$233K ﹤0.01%
2,781
-6,384
-70% -$586K
DCGO icon
2740
DocGo
DCGO
$62.6M
$233K ﹤0.01%
88,104
-85,596
-49% -$343K
PRLB icon
2741
Protolabs
PRLB
$2.13B
$231K ﹤0.01%
6,600
-8,371
-56% -$330K
REYN icon
2742
Reynolds Consumer Products
REYN
$5.59B
$230K ﹤0.01%
9,659
-125,006
-93% -$3.15M
AORT icon
2743
Artivion
AORT
$1.32B
$230K ﹤0.01%
+9,340
New +$259K
KLTR icon
2744
Kaltura
KLTR
$267M
$229K ﹤0.01%
+122,054
New +$273K
VERA icon
2745
Vera Therapeutics
VERA
$2.36B
$229K ﹤0.01%
9,551
-31,900
-77% -$1.03M
RDVT icon
2746
Red Violet
RDVT
$924M
$229K ﹤0.01%
6,093
-1,362
-18% -$51.3K
RIGL icon
2747
Rigel Pharmaceuticals
RIGL
$750M
$228K ﹤0.01%
12,678
-48,235
-79% -$979K
NATR icon
2748
Nature's Sunshine
NATR
$288M
$226K ﹤0.01%
18,016
-2,215
-11% -$31.1K
KMDA icon
2749
Kamada
KMDA
$419M
$225K ﹤0.01%
+34,090
New +$243K
STC icon
2750
Stewart Information Services
STC
$2.08B
$225K ﹤0.01%
3,151
-561
-15% -$38K

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Two Sigma Investments's Q1 2025 Portfolio in Review

As of Q1 2025, Two Sigma Investments held 3,617 positions worth $46.8B, up 2% from $45.9B the previous quarter. Its ten largest holdings account for 8.1% of the portfolio.

Two Sigma Investments deployed $2.08B of net new capital in Q1 2025, opening 458 new positions and adding to 1,225 existing holdings. Its largest new stake was Advanced Micro Devices: 2,246,952 shares worth $231M.

By sector, the portfolio is most concentrated in Technology at 18% of assets, up from 16% a quarter earlier, followed by Healthcare and Financials.

On the sell side, the largest reduction was Eli Lilly, an estimated $255M trimmed.

  • Two Sigma Investments's largest Q1 2025 buy was Advanced Micro Devices: 2,246,952 shares worth $231M.
  • Two Sigma Investments added most to State Street SPDR S&P 500 ETF Trust in Q1 2025, an estimated $510M increase.
  • Two Sigma Investments's biggest Q1 2025 reduction was Eli Lilly, cutting an estimated $255M.
  • Two Sigma Investments fully exited Coinbase in Q1 2025, selling an estimated $45M.
  • Two Sigma Investments's ten largest holdings make up 8.1% of its $46.8B portfolio in Q1 2025.
  • Two Sigma Investments opened 458 new positions and closed 453 in Q1 2025.
  • Two Sigma Investments's portfolio value rose 2% quarter-over-quarter to $46.8B.

Based on Two Sigma Investments's 13F filing for Q1 2025, filed 15 May 2025.