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Two Sigma Investments

Two Sigma Investments Portfolio holdings

AUM $124B
1-Year Est. Return 33.93%
This Fund
S&P 500
This Quarter Est. Return
-0.88%
1 Year Est. Return
+33.93%
3 Year Est. Return
+96.56%
5 Year Est. Return
+105.93%
10 Year Est. Return
+538.88%
AUM
$33.9B
AUM Growth
-$12.9B
Cap. Flow
-$11.3B
Cap. Flow %
-33.44%
Top 10 Hldgs %
7.18%
Holding
4,846
New
656
Increased
881
Reduced
976
Closed
2,305

Top Buys

Rank Stock Value
1
CSCO icon
Cisco
CSCO
+$226M
2
JPM icon
JPMorgan Chase
JPM
+$212M
3
TSM icon
TSMC
TSM
+$204M
4
OXY icon
Occidental Petroleum
OXY
+$194M
5
AAPL icon
Apple
AAPL
+$180M

Sector Composition

Rank Sector Weight
1 Technology 18.43%
2 Healthcare 14.66%
3 Industrials 10.19%
4 Consumer Discretionary 10.1%
5 Financials 9.1%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
BOLT icon
2476
Bolt Biotherapeutics
BOLT
$7.67M
$49K ﹤0.01%
890
-385
-30% -$25.9K
CYCN icon
2477
Cyclerion Therapeutics
CYCN
$16.8M
$47K ﹤0.01%
2,120
-4,759
-69% -$115K
SLNO
2478
DELISTED
Soleno Therapeutics
SLNO
$47K ﹤0.01%
13,903
-6,733
-33% -$34.9K
TOVX icon
2479
Theriva Biologics
TOVX
$10.6M
$47K ﹤0.01%
653
+317
+94% +$21.6K
WRAP icon
2480
Wrap Technologies
WRAP
$102M
$47K ﹤0.01%
17,228
-781
-4% -$2.17K
INZY
2481
DELISTED
Inozyme Pharma
INZY
$45K ﹤0.01%
+10,916
New +$64.3K
WHLR
2482
Wheeler Real Estate Investment Trust
WHLR
$390K
0
PXS icon
2483
Pyxis Tankers
PXS
$50.7M
$43K ﹤0.01%
+20,606
New +$45.3K
AWH
2484
DELISTED
Aspira Women's Health Inc. Common Stock
AWH
$42K ﹤0.01%
2,719
-23,406
-90% -$406K
GYRE icon
2485
Gyre Therapeutics
GYRE
$749M
$41K ﹤0.01%
8,364
-32,776
-80% -$162K
TLMD
2486
DELISTED
SOC Telemed, Inc. Class A Common Stock
TLMD
$41K ﹤0.01%
+13,661
New +$30.1K
AEMD icon
2487
Aethlon Medical
AEMD
$1.62M
$40K ﹤0.01%
7
-11
-61% -$65.6K
CNCE
2488
DELISTED
Concert Pharmaceuticals, Inc.
CNCE
$40K ﹤0.01%
12,000
-78,900
-87% -$250K
FTK icon
2489
Flotek Industries
FTK
$1.36B
$38K ﹤0.01%
+5,083
New +$36.3K
INM icon
2490
InMed Pharmaceuticals
INM
$7.53M
$37K ﹤0.01%
79
-184
-70% -$96.6K
REVB icon
2491
Revelation Biosciences
REVB
$4.42M
0
QTNT
2492
DELISTED
Quotient Limited Ordinary Shares
QTNT
$36K ﹤0.01%
760
-3,167
-81% -$189K
APRE icon
2493
Aprea Therapeutics
APRE
$7.98M
$35K ﹤0.01%
+931
New +$38.2K
RGLS
2494
DELISTED
Regulus Therapeutics
RGLS
$34K ﹤0.01%
11,444
+5,913
+107% +$15.4K
EDSA icon
2495
Edesa Biotech
EDSA
$50.5M
$33K ﹤0.01%
1,587
-215
-12% -$5.96K
TKLF
2496
Yoshitsu Co
TKLF
$7.87M
$33K ﹤0.01%
+1,570
New +$77.1K
GOVX icon
2497
GeoVax Labs
GOVX
$3.93M
$31K ﹤0.01%
+73
New +$58K
SUPV
2498
Grupo Supervielle
SUPV
$742M
$31K ﹤0.01%
+15,144
New +$28.9K
VGFC
2499
DELISTED
The Very Good Food Company
VGFC
$30K ﹤0.01%
58,286
-61,492
-51% -$35.5K
TMQ
2500
Trilogy Metals
TMQ
$670M
$29K ﹤0.01%
+27,896
New +$37K

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Two Sigma Investments's Q1 2022 Portfolio in Review

As of Q1 2022, Two Sigma Investments held 4,846 positions worth $33.9B, down 28% from $46.8B the previous quarter. Its ten largest holdings account for 7.2% of the portfolio.

Two Sigma Investments withdrew a net $11.3B in Q1 2022, closing 2,305 positions and reducing 976 holdings. Its most notable exit was Pfizer, an estimated $271M position sold in full.

By sector, the portfolio is most concentrated in Technology at 18% of assets, up from 17% a quarter earlier, followed by Healthcare and Industrials.

Against the trend, Two Sigma Investments opened a new position in Cisco worth $223M.

  • Two Sigma Investments's largest Q1 2022 buy was Cisco: 4,001,362 shares worth $223M.
  • Two Sigma Investments added most to JPMorgan Chase in Q1 2022, an estimated $212M increase.
  • Two Sigma Investments's biggest Q1 2022 reduction was Coca-Cola, cutting an estimated $225M.
  • Two Sigma Investments fully exited Pfizer in Q1 2022, selling an estimated $271M.
  • Two Sigma Investments's ten largest holdings make up 7.2% of its $33.9B portfolio in Q1 2022.
  • Two Sigma Investments opened 656 new positions and closed 2,305 in Q1 2022.
  • Two Sigma Investments's portfolio value fell 28% quarter-over-quarter to $33.9B.

Based on Two Sigma Investments's 13F filing for Q1 2022, filed 16 May 2022.