Two Sigma Investments
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Two Sigma Investments’s Rallybio RLYB Stock Holding History

Two Sigma Investments’s Portfolio RLYB Stock Details RLYB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$266K Buy
+16,619
New +$214K ﹤0.01% 4607
2026
Q1 		– Sell
-4,625
Closed -$25.4K – 4874
2025
Q4 		$25.4K Buy
4,625
+1,943
+72% +$10K ﹤0.01% 3979
2025
Q3 		$10.7K Sell
2,682
-5,291
-66% -$22.2K ﹤0.01% 3622
2025
Q2 		$21.6K Sell
7,973
-366
-4% -$970 ﹤0.01% 3115
2025
Q1 		$43.7K Sell
8,339
-1,262
-13% -$7.97K ﹤0.01% 3057
2024
Q4 		$73.7K Sell
9,601
-1,190
-11% -$9.97K ﹤0.01% 3003
2024
Q3 		$101K Buy
10,791
+4,134
+62% +$39.8K ﹤0.01% 2897
2024
Q2 		$71.4K Buy
+6,657
New +$90.2K ﹤0.01% 2859

Other funds holding RLYB

ACM
ADAR1 Capital Management Austin, Texas $2.19B AUM 374.99% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
Viking Global Investors
Viking Global Investors Stamford, Connecticut $35.1B AUM 21.36% 1-Year Est. Return
TGA
TPG GP A Fort Worth, Texas $5B AUM 58.56% 1-Year Est. Return
PBPIA
Pivotal bioVenture Partners Investment Advisor San Francisco, California $308M AUM 120.89% 1-Year Est. Return
Renaissance Technologies
Renaissance Technologies New York $72.6B AUM 54.88% 1-Year Est. Return
NCM
Nantahala Capital Management New Canaan, Connecticut $3.01B AUM 119.46% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
AC
Almitas Capital Santa Monica, California $417M AUM 22.81% 1-Year Est. Return
RC
Rangeley Capital New Canaan, Connecticut $109M AUM 97.13% 1-Year Est. Return

Two Sigma Investments's RLYB Position: Q2 2026 in Review

Two Sigma Investments opened a new position in Rallybio (RLYB) in Q2 2026: 16,619 shares worth $266K. The stake represents ﹤0.01% of the portfolio and ranks #4607 among its holdings. This is a return to the name: Two Sigma Investments previously reported a position in RLYB as recently as Q4 2025.

Two Sigma Investments first reported a position in RLYB in Q2 2024 and has held it in 8 quarters since. 37 funds tracked by Wall St. Rank hold RLYB as of Q2 2026.

  • Two Sigma Investments held 16,619 shares of Rallybio worth $266K as of Q2 2026.
  • Rallybio was a new Two Sigma Investments position in Q2 2026.
  • Rallybio made up ﹤0.01% of Two Sigma Investments's portfolio in Q2 2026, its #4607 holding.
  • Two Sigma Investments first reported a position in Rallybio in Q2 2024 and has held it in 8 quarters since.
  • 37 funds tracked by Wall St. Rank held Rallybio as of Q2 2026.

Based on Two Sigma Investments's 13F filing for Q2 2026, filed 14 Aug 2026.