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Two Sigma Advisers

Two Sigma Advisers Portfolio holdings

AUM $51.4B
1-Year Est. Return 31.07%
This Fund
S&P 500
This Quarter Est. Return
-3%
1 Year Est. Return
+31.07%
3 Year Est. Return
+128.94%
5 Year Est. Return
+161.75%
10 Year Est. Return
+607.04%
AUM
$44.4B
AUM Growth
+$1.2B
Cap. Flow
+$3.32B
Cap. Flow %
7.48%
Top 10 Hldgs %
17.65%
Holding
2,641
New
312
Increased
1,037
Reduced
994
Closed
281

Top Buys

Rank Stock Value
1
AVGO icon
Broadcom
AVGO
+$519M
2
CRM icon
Salesforce
CRM
+$460M
3
REGN icon
Regeneron Pharmaceuticals
REGN
+$381M
4
BSX icon
Boston Scientific
BSX
+$347M
5
ISRG icon
Intuitive Surgical
ISRG
+$319M

Top Sells

Rank Stock Value
1
V icon
Visa
V
+$555M
2
LLY icon
Eli Lilly
LLY
+$536M
3
META icon
Meta Platforms (Facebook)
META
+$433M
4
PGR icon
Progressive
PGR
+$330M
5
LRCX icon
Lam Research
LRCX
+$294M

Sector Composition

Rank Sector Weight
1 Technology 25.86%
2 Healthcare 15.38%
3 Financials 14.3%
4 Consumer Discretionary 11.43%
5 Industrials 10.56%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ALDX icon
2151
Aldeyra Therapeutics
ALDX
$97.1M
$190K ﹤0.01%
33,100
-92,200
-74% -$545K
CGEM icon
2152
Cullinan Oncology
CGEM
$1.06B
$190K ﹤0.01%
25,100
+3,200
+15% +$30.7K
RRGB icon
2153
Red Robin
RRGB
$139M
$189K ﹤0.01%
+53,212
New +$273K
INGM
2154
Ingram Micro Holding
INGM
$6.94B
$186K ﹤0.01%
+10,500
New +$224K
TRML
2155
DELISTED
Tourmaline Bio
TRML
$186K ﹤0.01%
+12,219
New +$196K
CATO icon
2156
Cato Corp
CATO
$65.7M
$186K ﹤0.01%
55,800
-50,700
-48% -$170K
VOXX
2157
DELISTED
VOXX International Corporation Class A
VOXX
$185K ﹤0.01%
+24,686
New +$183K
FPH icon
2158
Five Point Holdings
FPH
$387M
$184K ﹤0.01%
34,500
+11,700
+51% +$61.6K
HUYA
2159
Huya Inc
HUYA
$558M
$184K ﹤0.01%
57,300
-4,900
-8% -$17.7K
AMWL icon
2160
American Well
AMWL
$180M
$183K ﹤0.01%
23,245
-17,800
-43% -$169K
ALAR
2161
Alarum Technologies
ALAR
$12.5M
$183K ﹤0.01%
+29,200
New +$253K
ETNB
2162
DELISTED
89bio
ETNB
$180K ﹤0.01%
24,800
-87,300
-78% -$763K
ICAD
2163
DELISTED
iCAD Inc
ICAD
$179K ﹤0.01%
+87,100
New +$221K
ARIS
2164
Aris Mining
ARIS
$2.87B
$179K ﹤0.01%
+38,600
New +$153K
FLWS icon
2165
1-800-Flowers.com
FLWS
$252M
$179K ﹤0.01%
30,300
+16,400
+118% +$121K
PANL icon
2166
Pangaea Logistics
PANL
$484M
$177K ﹤0.01%
37,100
-199,100
-84% -$1.05M
NMRA icon
2167
Neumora Therapeutics
NMRA
$306M
$176K ﹤0.01%
+176,200
New +$302K
MVBF icon
2168
MVB Financial
MVBF
$397M
$175K ﹤0.01%
10,080
-3,420
-25% -$64.4K
AXIA
2169
AXIA Energia
AXIA
$22.9B
$174K ﹤0.01%
30,940
+17,301
+127% +$88K
KLRS
2170
Kalaris Therapeutics
KLRS
$80.9M
$173K ﹤0.01%
21,581
-6
-0% -$59
HEPS
2171
D-Market Electronic Services & Trading
HEPS
$1.02B
$171K ﹤0.01%
60,000
-54,500
-48% -$177K
RSKD icon
2172
Riskified
RSKD
$719M
$169K ﹤0.01%
36,600
+7,000
+24% +$35.3K
LCNB icon
2173
LCNB Corp
LCNB
$289M
$169K ﹤0.01%
11,400
– –
SHEN icon
2174
Shenandoah Telecom
SHEN
$703M
$167K ﹤0.01%
+13,300
New +$156K
EYPT icon
2175
EyePoint Inc
EYPT
$999M
$163K ﹤0.01%
30,100
-74,400
-71% -$521K
85 86
87
88 89

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Two Sigma Advisers's Q1 2025 Portfolio in Review

As of Q1 2025, Two Sigma Advisers held 2,641 positions worth $44.4B, up 2.8% from $43.2B the previous quarter. Its ten largest holdings account for 18% of the portfolio.

Two Sigma Advisers deployed $3.32B of net new capital in Q1 2025, opening 312 new positions and adding to 1,037 existing holdings. Its largest new stake was Regeneron Pharmaceuticals: 553,800 shares worth $351M.

By sector, the portfolio is most concentrated in Technology at 26% of assets, up from 25% a quarter earlier, followed by Healthcare and Financials.

On the sell side, the largest reduction was Visa, an estimated $555M trimmed.

  • Two Sigma Advisers's largest Q1 2025 buy was Regeneron Pharmaceuticals: 553,800 shares worth $351M.
  • Two Sigma Advisers added most to Broadcom in Q1 2025, an estimated $519M increase.
  • Two Sigma Advisers's biggest Q1 2025 reduction was Visa, cutting an estimated $555M.
  • Two Sigma Advisers fully exited Abbott in Q1 2025, selling an estimated $158M.
  • Two Sigma Advisers's ten largest holdings make up 18% of its $44.4B portfolio in Q1 2025.
  • Two Sigma Advisers opened 312 new positions and closed 281 in Q1 2025.
  • Two Sigma Advisers's portfolio value rose 2.8% quarter-over-quarter to $44.4B.

Based on Two Sigma Advisers's 13F filing for Q1 2025, filed 15 May 2025.