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Two Sigma Advisers

Two Sigma Advisers Portfolio holdings

AUM $51.4B
1-Year Est. Return 31.07%
This Fund
S&P 500
This Quarter Est. Return
-3%
1 Year Est. Return
+31.07%
3 Year Est. Return
+128.94%
5 Year Est. Return
+161.75%
10 Year Est. Return
+607.04%
AUM
$44.4B
AUM Growth
+$1.2B
Cap. Flow
+$3.32B
Cap. Flow %
7.48%
Top 10 Hldgs %
17.65%
Holding
2,641
New
312
Increased
1,037
Reduced
994
Closed
281

Top Buys

Rank Stock Value
1
AVGO icon
Broadcom
AVGO
+$519M
2
CRM icon
Salesforce
CRM
+$460M
3
REGN icon
Regeneron Pharmaceuticals
REGN
+$381M
4
BSX icon
Boston Scientific
BSX
+$347M
5
ISRG icon
Intuitive Surgical
ISRG
+$319M

Top Sells

Rank Stock Value
1
V icon
Visa
V
+$555M
2
LLY icon
Eli Lilly
LLY
+$536M
3
META icon
Meta Platforms (Facebook)
META
+$433M
4
PGR icon
Progressive
PGR
+$330M
5
LRCX icon
Lam Research
LRCX
+$294M

Sector Composition

Rank Sector Weight
1 Technology 25.86%
2 Healthcare 15.38%
3 Financials 14.3%
4 Consumer Discretionary 11.43%
5 Industrials 10.56%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
AVBP icon
1951
ArriVent BioPharma
AVBP
$1.4B
$333K ﹤0.01%
+18,000
New +$441K
OGS icon
1952
ONE Gas
OGS
$5.01B
$333K ﹤0.01%
+4,400
New +$317K
WLFC icon
1953
Willis Lease Finance
WLFC
$1.65B
$332K ﹤0.01%
+6,300
New +$400K
TFSL icon
1954
TFS Financial
TFSL
$5.11B
$332K ﹤0.01%
+26,772
New +$343K
HWC icon
1955
Hancock Whitney
HWC
$6.19B
$330K ﹤0.01%
6,300
-24,300
-79% -$1.37M
AVDX
1956
DELISTED
AvidXchange
AVDX
$330K ﹤0.01%
38,900
+6,400
+20% +$59.1K
EQR icon
1957
Equity Residential
EQR
$25.8B
$329K ﹤0.01%
4,600
-8,600
-65% -$607K
BSRR icon
1958
Sierra Bancorp
BSRR
$532M
$329K ﹤0.01%
11,800
-700
-6% -$20.7K
TALO icon
1959
Talos Energy
TALO
$2.38B
$326K ﹤0.01%
+33,500
New +$318K
MNSB icon
1960
MainStreet Bancshares
MNSB
$167M
$323K ﹤0.01%
19,300
-300
-2% -$5.04K
APLT
1961
DELISTED
Applied Therapeutics
APLT
$322K ﹤0.01%
+658,400
New +$388K
NATR icon
1962
Nature's Sunshine
NATR
$362M
$321K ﹤0.01%
25,600
-2,000
-7% -$28.1K
GRBK icon
1963
Green Brick Partners
GRBK
$3.09B
$321K ﹤0.01%
5,500
-800
-13% -$47.3K
ANGO icon
1964
AngioDynamics
ANGO
$605M
$320K ﹤0.01%
34,100
-226,600
-87% -$2.38M
SANM icon
1965
Sanmina
SANM
$8.78B
$320K ﹤0.01%
4,200
-600
-13% -$48.7K
TX icon
1966
Ternium
TX
$9.43B
$318K ﹤0.01%
10,200
+1,200
+13% +$36.3K
NU icon
1967
Nu Holdings
NU
$67.8B
$317K ﹤0.01%
31,000
-1,099,600
-97% -$13M
NNDM
1968
Nano Dimension
NNDM
$314M
$317K ﹤0.01%
199,100
-92,900
-32% -$210K
CTS icon
1969
CTS Corp
CTS
$1.76B
$316K ﹤0.01%
7,600
-200
-3% -$9.36K
KZR
1970
DELISTED
Kezar Life Sciences
KZR
$315K ﹤0.01%
64,509
-35,632
-36% -$216K
CASS icon
1971
Cass Information Systems
CASS
$716M
$314K ﹤0.01%
7,249
-6,700
-48% -$284K
ISTR icon
1972
Investar Holding Corp
ISTR
$411M
$313K ﹤0.01%
+17,800
New +$334K
TRUP icon
1973
Trupanion
TRUP
$1.13B
$313K ﹤0.01%
8,400
-33,000
-80% -$1.37M
KW
1974
DELISTED
Kennedy-Wilson Holdings
KW
$312K ﹤0.01%
36,000
+2,400
+7% +$21.9K
ANIK icon
1975
Anika Therapeutics
ANIK
$215M
$312K ﹤0.01%
20,783
-5,500
-21% -$91.5K
77 78
79
80 81

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CWM
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FAF
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Two Sigma Advisers's Q1 2025 Portfolio in Review

As of Q1 2025, Two Sigma Advisers held 2,641 positions worth $44.4B, up 2.8% from $43.2B the previous quarter. Its ten largest holdings account for 18% of the portfolio.

Two Sigma Advisers deployed $3.32B of net new capital in Q1 2025, opening 312 new positions and adding to 1,037 existing holdings. Its largest new stake was Regeneron Pharmaceuticals: 553,800 shares worth $351M.

By sector, the portfolio is most concentrated in Technology at 26% of assets, up from 25% a quarter earlier, followed by Healthcare and Financials.

On the sell side, the largest reduction was Visa, an estimated $555M trimmed.

  • Two Sigma Advisers's largest Q1 2025 buy was Regeneron Pharmaceuticals: 553,800 shares worth $351M.
  • Two Sigma Advisers added most to Broadcom in Q1 2025, an estimated $519M increase.
  • Two Sigma Advisers's biggest Q1 2025 reduction was Visa, cutting an estimated $555M.
  • Two Sigma Advisers fully exited Abbott in Q1 2025, selling an estimated $158M.
  • Two Sigma Advisers's ten largest holdings make up 18% of its $44.4B portfolio in Q1 2025.
  • Two Sigma Advisers opened 312 new positions and closed 281 in Q1 2025.
  • Two Sigma Advisers's portfolio value rose 2.8% quarter-over-quarter to $44.4B.

Based on Two Sigma Advisers's 13F filing for Q1 2025, filed 15 May 2025.