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Two Sigma Advisers

Two Sigma Advisers Portfolio holdings

AUM $51.4B
1-Year Est. Return 31.07%
This Fund
S&P 500
This Quarter Est. Return
-3%
1 Year Est. Return
+31.07%
3 Year Est. Return
+128.94%
5 Year Est. Return
+161.75%
10 Year Est. Return
+607.04%
AUM
$44.4B
AUM Growth
+$1.2B
Cap. Flow
+$3.32B
Cap. Flow %
7.48%
Top 10 Hldgs %
17.65%
Holding
2,641
New
312
Increased
1,037
Reduced
994
Closed
281

Top Buys

Rank Stock Value
1
AVGO icon
Broadcom
AVGO
+$519M
2
CRM icon
Salesforce
CRM
+$460M
3
REGN icon
Regeneron Pharmaceuticals
REGN
+$381M
4
BSX icon
Boston Scientific
BSX
+$347M
5
ISRG icon
Intuitive Surgical
ISRG
+$319M

Top Sells

Rank Stock Value
1
V icon
Visa
V
+$555M
2
LLY icon
Eli Lilly
LLY
+$536M
3
META icon
Meta Platforms (Facebook)
META
+$433M
4
PGR icon
Progressive
PGR
+$330M
5
LRCX icon
Lam Research
LRCX
+$294M

Sector Composition

Rank Sector Weight
1 Technology 25.86%
2 Healthcare 15.38%
3 Financials 14.3%
4 Consumer Discretionary 11.43%
5 Industrials 10.56%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
YMAB
1676
DELISTED
Y-mAbs Therapeutics
YMAB
$635K ﹤0.01%
143,300
+69,400
+94% +$403K
SILC icon
1677
Silicom
SILC
$201M
$634K ﹤0.01%
42,600
-100
-0.2% -$1.63K
INN
1678
Summit Hotel Properties
INN
$766M
$632K ﹤0.01%
116,900
-19,600
-14% -$125K
NUVB icon
1679
Nuvation Bio
NUVB
$2.29B
$631K ﹤0.01%
358,800
-117,600
-25% -$268K
FSP
1680
Franklin Street Properties
FSP
$49.9M
$631K ﹤0.01%
354,400
-62,700
-15% -$116K
LTRX icon
1681
Lantronix
LTRX
$223M
$630K ﹤0.01%
253,000
-57,100
-18% -$184K
TALK icon
1682
Talkspace
TALK
$874M
$630K ﹤0.01%
245,900
+15,300
+7% +$47.7K
PGNY icon
1683
Progyny
PGNY
$2.46B
$628K ﹤0.01%
28,100
-238,000
-89% -$5.13M
PRTH icon
1684
Priority Technology Holdings
PRTH
$554M
$626K ﹤0.01%
91,900
+64,100
+231% +$606K
CFR icon
1685
Cullen/Frost Bankers
CFR
$10.5B
$626K ﹤0.01%
5,000
+200
+4% +$26.9K
BJRI icon
1686
BJ's Restaurants
BJRI
$1.47B
$624K ﹤0.01%
18,200
+1,300
+8% +$46.1K
FATE icon
1687
Fate Therapeutics
FATE
$275M
$622K ﹤0.01%
787,000
-41,100
-5% -$50.4K
AAT
1688
American Assets Trust
AAT
$1.46B
$619K ﹤0.01%
30,729
+12,700
+70% +$286K
EMN icon
1689
Eastman Chemical
EMN
$7.69B
$617K ﹤0.01%
7,000
-4,800
-41% -$453K
OBE
1690
Obsidian Energy
OBE
$656M
$616K ﹤0.01%
105,200
+5,000
+5% +$27.6K
CMI icon
1691
Cummins
CMI
$83.6B
$616K ﹤0.01%
+1,964
New +$692K
TG icon
1692
Tredegar Corp
TG
$260M
$614K ﹤0.01%
79,758
-29,342
-27% -$226K
NIU
1693
Niu Technologies
NIU
$200M
$613K ﹤0.01%
150,352
+139,052
+1,231% +$346K
BRX icon
1694
Brixmor Property Group
BRX
$9.72B
$613K ﹤0.01%
23,100
-61,900
-73% -$1.65M
KRO icon
1695
KRONOS Worldwide
KRO
$712M
$612K ﹤0.01%
81,800
+1,700
+2% +$15K
KC
1696
Kingsoft Cloud Holdings
KC
$2.96B
$612K ﹤0.01%
42,600
+15,400
+57% +$231K
DOCS icon
1697
Doximity
DOCS
$3.89B
$609K ﹤0.01%
+10,500
New +$663K
ANTX icon
1698
AN2 Therapeutics
ANTX
$181M
$605K ﹤0.01%
445,004
-83,296
-16% -$105K
JOUT icon
1699
Johnson Outdoors
JOUT
$496M
$604K ﹤0.01%
24,334
+13,500
+125% +$394K
FVR
1700
FrontView REIT
FVR
$488M
$604K ﹤0.01%
47,200
-900
-2% -$14.7K
66 67
68
69 70

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Two Sigma Advisers's Q1 2025 Portfolio in Review

As of Q1 2025, Two Sigma Advisers held 2,641 positions worth $44.4B, up 2.8% from $43.2B the previous quarter. Its ten largest holdings account for 18% of the portfolio.

Two Sigma Advisers deployed $3.32B of net new capital in Q1 2025, opening 312 new positions and adding to 1,037 existing holdings. Its largest new stake was Regeneron Pharmaceuticals: 553,800 shares worth $351M.

By sector, the portfolio is most concentrated in Technology at 26% of assets, up from 25% a quarter earlier, followed by Healthcare and Financials.

On the sell side, the largest reduction was Visa, an estimated $555M trimmed.

  • Two Sigma Advisers's largest Q1 2025 buy was Regeneron Pharmaceuticals: 553,800 shares worth $351M.
  • Two Sigma Advisers added most to Broadcom in Q1 2025, an estimated $519M increase.
  • Two Sigma Advisers's biggest Q1 2025 reduction was Visa, cutting an estimated $555M.
  • Two Sigma Advisers fully exited Abbott in Q1 2025, selling an estimated $158M.
  • Two Sigma Advisers's ten largest holdings make up 18% of its $44.4B portfolio in Q1 2025.
  • Two Sigma Advisers opened 312 new positions and closed 281 in Q1 2025.
  • Two Sigma Advisers's portfolio value rose 2.8% quarter-over-quarter to $44.4B.

Based on Two Sigma Advisers's 13F filing for Q1 2025, filed 15 May 2025.