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Two Sigma Advisers

Two Sigma Advisers Portfolio holdings

AUM $51.4B
1-Year Est. Return 31.07%
This Fund
S&P 500
This Quarter Est. Return
-3%
1 Year Est. Return
+31.07%
3 Year Est. Return
+128.94%
5 Year Est. Return
+161.75%
10 Year Est. Return
+607.04%
AUM
$44.4B
AUM Growth
+$1.2B
Cap. Flow
+$3.32B
Cap. Flow %
7.48%
Top 10 Hldgs %
17.65%
Holding
2,641
New
312
Increased
1,037
Reduced
994
Closed
281

Top Buys

Rank Stock Value
1
AVGO icon
Broadcom
AVGO
+$519M
2
CRM icon
Salesforce
CRM
+$460M
3
REGN icon
Regeneron Pharmaceuticals
REGN
+$381M
4
BSX icon
Boston Scientific
BSX
+$347M
5
ISRG icon
Intuitive Surgical
ISRG
+$319M

Top Sells

Rank Stock Value
1
V icon
Visa
V
+$555M
2
LLY icon
Eli Lilly
LLY
+$536M
3
META icon
Meta Platforms (Facebook)
META
+$433M
4
PGR icon
Progressive
PGR
+$330M
5
LRCX icon
Lam Research
LRCX
+$294M

Sector Composition

Rank Sector Weight
1 Technology 25.86%
2 Healthcare 15.38%
3 Financials 14.3%
4 Consumer Discretionary 11.43%
5 Industrials 10.56%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
MDXG icon
1426
MiMedx Group
MDXG
$630M
$1.11M ﹤0.01%
146,700
-52,600
-26% -$439K
FLGT icon
1427
Fulgent Genetics
FLGT
$558M
$1.11M ﹤0.01%
65,800
-17,200
-21% -$293K
CRBG icon
1428
Corebridge Financial
CRBG
$14.3B
$1.11M ﹤0.01%
35,200
-274,300
-89% -$8.88M
ARQT icon
1429
Arcutis Biotherapeutics
ARQT
$3.48B
$1.11M ﹤0.01%
+70,800
New +$997K
MBC icon
1430
MasterBrand
MBC
$1.09B
$1.1M ﹤0.01%
84,600
-193,000
-70% -$2.93M
FRST icon
1431
Primis Financial Corp
FRST
$399M
$1.1M ﹤0.01%
112,862
+15,600
+16% +$166K
MLCO icon
1432
Melco Resorts & Entertainment
MLCO
$2.21B
$1.1M ﹤0.01%
209,100
+81,100
+63% +$457K
FSBC icon
1433
Five Star Bancorp
FSBC
$1.01B
$1.1M ﹤0.01%
39,400
+2,600
+7% +$77.4K
IHS icon
1434
IHS Holding
IHS
$2.78B
$1.09M ﹤0.01%
209,700
+195,300
+1,356% +$748K
LKFT
1435
Lakefront Biotherapeutics American Depositary Shares
LKFT
$1.82B
$1.09M ﹤0.01%
+43,500
New +$1.1M
SUPN icon
1436
Supernus Pharmaceuticals
SUPN
$2.7B
$1.09M ﹤0.01%
33,300
+25,500
+327% +$904K
SPOK icon
1437
Spok Holdings
SPOK
$229M
$1.09M ﹤0.01%
66,300
+33,500
+102% +$545K
QVCGA
1438
DELISTED
QVC Group Inc Series A
QVCGA
$1.09M ﹤0.01%
108,375
-18,480
-15% -$294K
HIG icon
1439
Hartford Financial Services
HIG
$39.9B
$1.09M ﹤0.01%
8,800
-29,700
-77% -$3.41M
ASH icon
1440
Ashland
ASH
$3.34B
$1.09M ﹤0.01%
18,300
-2,200
-11% -$140K
APLE icon
1441
Apple Hospitality REIT
APLE
$3.97B
$1.08M ﹤0.01%
83,900
-23,600
-22% -$345K
RM icon
1442
Regional Management Corp
RM
$390M
$1.08M ﹤0.01%
35,918
+800
+2% +$26.8K
HY icon
1443
Hyster-Yale Materials Handling
HY
$576M
$1.08M ﹤0.01%
26,000
+18,800
+261% +$935K
VNDA icon
1444
Vanda Pharmaceuticals
VNDA
$304M
$1.08M ﹤0.01%
235,200
+78,900
+50% +$368K
FRME icon
1445
First Merchants
FRME
$2.69B
$1.07M ﹤0.01%
26,574
+16,200
+156% +$675K
MFIN icon
1446
Medallion Financial
MFIN
$230M
$1.06M ﹤0.01%
122,200
-2,900
-2% -$25.6K
AGYS icon
1447
Agilysys
AGYS
$3.21B
$1.06M ﹤0.01%
14,600
+9,800
+204% +$896K
GHC icon
1448
Graham Holdings Company
GHC
$5.31B
$1.06M ﹤0.01%
1,101
-800
-42% -$744K
SPXC icon
1449
SPX Corp
SPXC
$9.39B
$1.06M ﹤0.01%
+8,200
New +$1.17M
RES icon
1450
RPC Inc
RES
$1.13B
$1.05M ﹤0.01%
190,842
+179,000
+1,512% +$1.07M
56 57
58
59 60

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Two Sigma Advisers's Q1 2025 Portfolio in Review

As of Q1 2025, Two Sigma Advisers held 2,641 positions worth $44.4B, up 2.8% from $43.2B the previous quarter. Its ten largest holdings account for 18% of the portfolio.

Two Sigma Advisers deployed $3.32B of net new capital in Q1 2025, opening 312 new positions and adding to 1,037 existing holdings. Its largest new stake was Regeneron Pharmaceuticals: 553,800 shares worth $351M.

By sector, the portfolio is most concentrated in Technology at 26% of assets, up from 25% a quarter earlier, followed by Healthcare and Financials.

On the sell side, the largest reduction was Visa, an estimated $555M trimmed.

  • Two Sigma Advisers's largest Q1 2025 buy was Regeneron Pharmaceuticals: 553,800 shares worth $351M.
  • Two Sigma Advisers added most to Broadcom in Q1 2025, an estimated $519M increase.
  • Two Sigma Advisers's biggest Q1 2025 reduction was Visa, cutting an estimated $555M.
  • Two Sigma Advisers fully exited Abbott in Q1 2025, selling an estimated $158M.
  • Two Sigma Advisers's ten largest holdings make up 18% of its $44.4B portfolio in Q1 2025.
  • Two Sigma Advisers opened 312 new positions and closed 281 in Q1 2025.
  • Two Sigma Advisers's portfolio value rose 2.8% quarter-over-quarter to $44.4B.

Based on Two Sigma Advisers's 13F filing for Q1 2025, filed 15 May 2025.