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Two Sigma Advisers

Two Sigma Advisers Portfolio holdings

AUM $51.4B
1-Year Est. Return 31.07%
This Fund
S&P 500
This Quarter Est. Return
-3%
1 Year Est. Return
+31.07%
3 Year Est. Return
+128.94%
5 Year Est. Return
+161.75%
10 Year Est. Return
+607.04%
AUM
$44.4B
AUM Growth
+$1.2B
Cap. Flow
+$3.32B
Cap. Flow %
7.48%
Top 10 Hldgs %
17.65%
Holding
2,641
New
312
Increased
1,037
Reduced
994
Closed
281

Top Buys

Rank Stock Value
1
AVGO icon
Broadcom
AVGO
+$519M
2
CRM icon
Salesforce
CRM
+$460M
3
REGN icon
Regeneron Pharmaceuticals
REGN
+$381M
4
BSX icon
Boston Scientific
BSX
+$347M
5
ISRG icon
Intuitive Surgical
ISRG
+$319M

Top Sells

Rank Stock Value
1
V icon
Visa
V
+$555M
2
LLY icon
Eli Lilly
LLY
+$536M
3
META icon
Meta Platforms (Facebook)
META
+$433M
4
PGR icon
Progressive
PGR
+$330M
5
LRCX icon
Lam Research
LRCX
+$294M

Sector Composition

Rank Sector Weight
1 Technology 25.86%
2 Healthcare 15.38%
3 Financials 14.3%
4 Consumer Discretionary 11.43%
5 Industrials 10.56%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
TSLA icon
26
Tesla
TSLA
$1.24T
$372M 0.84%
1,434,093
+153,000
+12% +$51M
REGN icon
27
Regeneron Pharmaceuticals
REGN
$68.8B
$351M 0.79%
+553,800
New +$381M
ISRG icon
28
Intuitive Surgical
ISRG
$121B
$347M 0.78%
699,900
+576,800
+469% +$319M
NVO
29
Novo Nordisk
NVO
$216B
$337M 0.76%
4,856,800
+3,835,100
+375% +$317M
META icon
30
Meta Platforms (Facebook)
META
$1.51T
$328M 0.74%
569,500
-670,400
-54% -$433M
ICE icon
31
Intercontinental Exchange
ICE
$82.4B
$316M 0.71%
1,832,000
+221,000
+14% +$36.2M
AMGN icon
32
Amgen
AMGN
$203B
$312M 0.7%
1,001,400
-544,200
-35% -$161M
MRK icon
33
Merck
MRK
$324B
$295M 0.66%
3,288,600
-1,598,500
-33% -$149M
HUM icon
34
Humana
HUM
$46.7B
$278M 0.63%
1,052,480
+146,200
+16% +$39.5M
ABNB icon
35
Airbnb
ABNB
$83.7B
$274M 0.62%
2,290,500
-789,800
-26% -$106M
TMO icon
36
Thermo Fisher Scientific
TMO
$211B
$263M 0.59%
529,200
-404,000
-43% -$219M
SPOT icon
37
Spotify
SPOT
$99.2B
$247M 0.56%
449,700
+94,600
+27% +$52.9M
HOOD icon
38
Robinhood
HOOD
$85.2B
$240M 0.54%
5,771,500
-4,928,100
-46% -$234M
CVNA icon
39
Carvana
CVNA
$43.3B
$227M 0.51%
5,418,675
-2,966,500
-35% -$131M
CMCSA icon
40
Comcast
CMCSA
$79.1B
$224M 0.5%
6,061,300
+5,637,700
+1,331% +$203M
IT icon
41
Gartner
IT
$9.41B
$220M 0.5%
524,900
+378,200
+258% +$186M
COST icon
42
Costco
COST
$415B
$220M 0.49%
232,400
-37,700
-14% -$36.8M
COP icon
43
ConocoPhillips
COP
$147B
$219M 0.49%
2,086,378
+1,987,878
+2,018% +$198M
WCN
44
Waste Connections
WCN
$42.8B
$215M 0.48%
1,100,950
+138,100
+14% +$25.6M
JNPR
45
DELISTED
Juniper Networks
JNPR
$213M 0.48%
5,890,900
+5,548,900
+1,622% +$203M
GD icon
46
General Dynamics
GD
$105B
$208M 0.47%
762,400
-54,600
-7% -$14.2M
CNC icon
47
Centene
CNC
$31.3B
$201M 0.45%
3,305,876
+1,995,700
+152% +$121M
MCK icon
48
McKesson
MCK
$98.5B
$199M 0.45%
295,183
+167,183
+131% +$103M
DG icon
49
Dollar General
DG
$25.9B
$198M 0.45%
2,251,899
+495,100
+28% +$37.5M
NFLX icon
50
Netflix
NFLX
$292B
$192M 0.43%
2,057,000
-2,562,000
-55% -$244M
1
2
3 4 5

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Two Sigma Advisers's Q1 2025 Portfolio in Review

As of Q1 2025, Two Sigma Advisers held 2,641 positions worth $44.4B, up 2.8% from $43.2B the previous quarter. Its ten largest holdings account for 18% of the portfolio.

Two Sigma Advisers deployed $3.32B of net new capital in Q1 2025, opening 312 new positions and adding to 1,037 existing holdings. Its largest new stake was Regeneron Pharmaceuticals: 553,800 shares worth $351M.

By sector, the portfolio is most concentrated in Technology at 26% of assets, up from 25% a quarter earlier, followed by Healthcare and Financials.

On the sell side, the largest reduction was Visa, an estimated $555M trimmed.

  • Two Sigma Advisers's largest Q1 2025 buy was Regeneron Pharmaceuticals: 553,800 shares worth $351M.
  • Two Sigma Advisers added most to Broadcom in Q1 2025, an estimated $519M increase.
  • Two Sigma Advisers's biggest Q1 2025 reduction was Visa, cutting an estimated $555M.
  • Two Sigma Advisers fully exited Abbott in Q1 2025, selling an estimated $158M.
  • Two Sigma Advisers's ten largest holdings make up 18% of its $44.4B portfolio in Q1 2025.
  • Two Sigma Advisers opened 312 new positions and closed 281 in Q1 2025.
  • Two Sigma Advisers's portfolio value rose 2.8% quarter-over-quarter to $44.4B.

Based on Two Sigma Advisers's 13F filing for Q1 2025, filed 15 May 2025.