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Two Sigma Advisers

Two Sigma Advisers Portfolio holdings

AUM $51.4B
1-Year Est. Return 31.07%
This Fund
S&P 500
This Quarter Est. Return
+8.84%
1 Year Est. Return
+31.07%
3 Year Est. Return
+128.94%
5 Year Est. Return
+161.75%
10 Year Est. Return
+607.04%
AUM
$35.8B
AUM Growth
+$1.27B
Cap. Flow
-$817M
Cap. Flow %
-2.28%
Top 10 Hldgs %
13.63%
Holding
2,806
New
288
Increased
941
Reduced
1,236
Closed
310

Top Buys

Rank Stock Value
1
AMZN icon
Amazon
AMZN
+$563M
2
MCD icon
McDonald's
MCD
+$357M
3
TSLA icon
Tesla
TSLA
+$268M
4
AMD icon
Advanced Micro Devices
AMD
+$253M
5
PYPL icon
PayPal
PYPL
+$250M

Top Sells

Rank Stock Value
1
JPM icon
JPMorgan Chase
JPM
+$485M
2
META icon
Meta Platforms (Facebook)
META
+$254M
3
MRK icon
Merck
MRK
+$217M
4
MSFT icon
Microsoft
MSFT
+$212M
5
BMY icon
Bristol-Myers Squibb
BMY
+$200M

Sector Composition

Rank Sector Weight
1 Technology 24.67%
2 Healthcare 17.85%
3 Industrials 11.58%
4 Financials 11.17%
5 Consumer Discretionary 10.46%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
NVTA
2751
DELISTED
Invitae Corporation
NVTA
– –
-680,389
Closed -$1.67M
MCOM
2752
DELISTED
micromobility.com Inc. Class A Common stock
MCOM
– –
-1
Closed -$4K
VAPO
2753
DELISTED
Vapotherm, Inc. Common Stock
VAPO
– –
-5,400
Closed -$68K
LMNL
2754
DELISTED
Liminal BioSciences Inc. Common Shares
LMNL
– –
-1,080
Closed -$5K
HARP
2755
DELISTED
Harpoon Therapeutics, Inc. Common Stock
HARP
– –
-5,120
Closed -$50K
FOCS
2756
DELISTED
Focus Financial Partners Inc. Class A
FOCS
– –
-19,400
Closed -$611K
AMRS
2757
DELISTED
Amyris Inc.
AMRS
– –
-309,701
Closed -$904K
MOBQ
2758
DELISTED
Mobiquity Technologies, Inc. Common Stock
MOBQ
– –
-913
Closed -$16K
NMTR
2759
DELISTED
9 Meters Biopharma
NMTR
– –
-650
Closed -$3K
LABP
2760
DELISTED
Landos Biopharma, Inc. Common Stock
LABP
– –
-1,980
Closed -$13K
ABB
2761
DELISTED
ABB Ltd
ABB
– –
-59,700
Closed -$1.53M
BIOC
2762
DELISTED
Biocept, Inc.
BIOC
– –
-467
Closed -$13K
MAXR
2763
DELISTED
Maxar Technologies Inc. Common Stock
MAXR
– –
-36,324
Closed -$680K
RUBY
2764
DELISTED
Rubius Therapeutics, Inc
RUBY
– –
-29,400
Closed -$13K
QUMU
2765
DELISTED
Qumu Corp.
QUMU
– –
-10,000
Closed -$6K
TTM
2766
DELISTED
Tata Motors Limited
TTM
– –
-12,200
Closed -$296K
AATC
2767
DELISTED
Autoscope Technologies Corporation Common Stock
AATC
– –
-17,700
Closed -$81K
MNRL
2768
DELISTED
Brigham Minerals, Inc. Class A Common Stock
MNRL
– –
-204,200
Closed -$5.04M
OTIC
2769
DELISTED
Otonomy, Inc.
OTIC
– –
-158,200
Closed -$47K
ABMD
2770
DELISTED
Abiomed Inc
ABMD
– –
-111,499
Closed -$27.4M
BTRS
2771
DELISTED
BTRS Holdings Inc. Class 1 Common Stock
BTRS
– –
-154,500
Closed -$1.43M
LOTZ
2772
DELISTED
CarLotz, Inc. Class A Common Stock
LOTZ
– –
-39,700
Closed -$12K
UPH
2773
DELISTED
UpHealth, Inc.
UPH
– –
-1,070
Closed -$6K
SWCH
2774
DELISTED
Switch, Inc. Class A Common Stock
SWCH
– –
-34,465
Closed -$1.16M
AGTC
2775
DELISTED
Applied Genetic Technologies Corporation
AGTC
– –
-104,749
Closed -$28K
109 110
111
112 113

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Two Sigma Advisers's Q4 2022 Portfolio in Review

As of Q4 2022, Two Sigma Advisers held 2,806 positions worth $35.8B, up 3.7% from $34.5B the previous quarter. Its ten largest holdings account for 14% of the portfolio.

Two Sigma Advisers's Q4 2022 filing shows 288 new, 941 increased, 1,236 reduced and 310 closed positions. Its largest new stake was Advanced Micro Devices: 3,833,640 shares worth $248M. The largest sale was JPMorgan Chase, an estimated $485M.

By sector, the portfolio is most concentrated in Technology at 25% of assets, down from 27% a quarter earlier, followed by Healthcare and Industrials.

  • Two Sigma Advisers's largest Q4 2022 buy was Advanced Micro Devices: 3,833,640 shares worth $248M.
  • Two Sigma Advisers added most to Amazon in Q4 2022, an estimated $563M increase.
  • Two Sigma Advisers's biggest Q4 2022 reduction was JPMorgan Chase, cutting an estimated $485M.
  • Two Sigma Advisers fully exited NVIDIA in Q4 2022, selling an estimated $140M.
  • Two Sigma Advisers's ten largest holdings make up 14% of its $35.8B portfolio in Q4 2022.
  • Two Sigma Advisers opened 288 new positions and closed 310 in Q4 2022.
  • Two Sigma Advisers's portfolio value rose 3.7% quarter-over-quarter to $35.8B.

Based on Two Sigma Advisers's 13F filing for Q4 2022, filed 14 Feb 2023.