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Two Sigma Advisers

Two Sigma Advisers Portfolio holdings

AUM $51.4B
1-Year Est. Return 31.07%
This Fund
S&P 500
This Quarter Est. Return
-3%
1 Year Est. Return
+31.07%
3 Year Est. Return
+128.94%
5 Year Est. Return
+161.75%
10 Year Est. Return
+607.04%
AUM
$44.4B
AUM Growth
+$1.2B
Cap. Flow
+$3.32B
Cap. Flow %
7.48%
Top 10 Hldgs %
17.65%
Holding
2,641
New
312
Increased
1,037
Reduced
994
Closed
281

Top Buys

Rank Stock Value
1
AVGO icon
Broadcom
AVGO
+$519M
2
CRM icon
Salesforce
CRM
+$460M
3
REGN icon
Regeneron Pharmaceuticals
REGN
+$381M
4
BSX icon
Boston Scientific
BSX
+$347M
5
ISRG icon
Intuitive Surgical
ISRG
+$319M

Top Sells

Rank Stock Value
1
V icon
Visa
V
+$555M
2
LLY icon
Eli Lilly
LLY
+$536M
3
META icon
Meta Platforms (Facebook)
META
+$433M
4
PGR icon
Progressive
PGR
+$330M
5
LRCX icon
Lam Research
LRCX
+$294M

Sector Composition

Rank Sector Weight
1 Technology 25.86%
2 Healthcare 15.38%
3 Financials 14.3%
4 Consumer Discretionary 11.43%
5 Industrials 10.56%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
NTR icon
2526
Nutrien
NTR
$33.6B
– –
-67,317
Closed -$3.01M
NUE icon
2527
Nucor
NUE
$58.4B
– –
-90,800
Closed -$10.6M
NVS icon
2528
Novartis
NVS
$302B
– –
-4,600
Closed -$448K
NXPI icon
2529
NXP Semiconductors
NXPI
$60.9B
– –
-83,500
Closed -$17.4M
OLLI icon
2530
Ollie's Bargain Outlet
OLLI
$4.3B
– –
-13,600
Closed -$1.49M
OM icon
2531
Outset Medical
OM
$86.8M
– –
-27,500
Closed -$458K
ONTO icon
2532
Onto Innovation
ONTO
$10.9B
– –
-2,075
Closed -$346K
ORLY icon
2533
O'Reilly Automotive
ORLY
$75.4B
– –
-21,000
Closed -$1.66M
OSW icon
2534
OneSpaWorld
OSW
$2.68B
– –
-122,600
Closed -$2.44M
OTLY
2535
Oatly Group
OTLY
$487M
– –
-3,065
Closed -$40.6K
PDFS icon
2536
PDF Solutions
PDFS
$1.75B
– –
-14,300
Closed -$387K
PHAT icon
2537
Phathom Pharmaceuticals
PHAT
$936M
– –
-133,700
Closed -$1.09M
PHM icon
2538
Pultegroup
PHM
$25.3B
– –
-8,400
Closed -$915K
PHR icon
2539
Phreesia
PHR
$694M
– –
-12,000
Closed -$302K
PLYA
2540
DELISTED
Playa Hotels & Resorts
PLYA
– –
-46,300
Closed -$586K
PPG icon
2541
PPG Industries
PPG
$25.1B
– –
-21,000
Closed -$2.51M
QFIN icon
2542
Qfin Holdings
QFIN
$1.68B
– –
-10,000
Closed -$384K
RANI icon
2543
Rani Therapeutics
RANI
$90.8M
– –
-110,163
Closed -$151K
RBBN icon
2544
Ribbon Communications
RBBN
$386M
– –
-21,800
Closed -$90.7K
RCKT icon
2545
Rocket Pharmaceuticals
RCKT
$334M
– –
-10,845
Closed -$136K
RDVT icon
2546
Red Violet
RDVT
$960M
– –
-10,200
Closed -$369K
REI icon
2547
Ring Energy
REI
$310M
– –
-11,500
Closed -$15.6K
RGEN icon
2548
Repligen
RGEN
$7.09B
– –
-134,800
Closed -$19.4M
RHP icon
2549
Ryman Hospitality Properties
RHP
$8.58B
– –
-2,000
Closed -$209K
RNAM
2550
DELISTED
Avidity Biosciences
RNAM
– –
-16,400
Closed -$477K
100 101
102
103 104

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Two Sigma Advisers's Q1 2025 Portfolio in Review

As of Q1 2025, Two Sigma Advisers held 2,641 positions worth $44.4B, up 2.8% from $43.2B the previous quarter. Its ten largest holdings account for 18% of the portfolio.

Two Sigma Advisers deployed $3.32B of net new capital in Q1 2025, opening 312 new positions and adding to 1,037 existing holdings. Its largest new stake was Regeneron Pharmaceuticals: 553,800 shares worth $351M.

By sector, the portfolio is most concentrated in Technology at 26% of assets, up from 25% a quarter earlier, followed by Healthcare and Financials.

On the sell side, the largest reduction was Visa, an estimated $555M trimmed.

  • Two Sigma Advisers's largest Q1 2025 buy was Regeneron Pharmaceuticals: 553,800 shares worth $351M.
  • Two Sigma Advisers added most to Broadcom in Q1 2025, an estimated $519M increase.
  • Two Sigma Advisers's biggest Q1 2025 reduction was Visa, cutting an estimated $555M.
  • Two Sigma Advisers fully exited Abbott in Q1 2025, selling an estimated $158M.
  • Two Sigma Advisers's ten largest holdings make up 18% of its $44.4B portfolio in Q1 2025.
  • Two Sigma Advisers opened 312 new positions and closed 281 in Q1 2025.
  • Two Sigma Advisers's portfolio value rose 2.8% quarter-over-quarter to $44.4B.

Based on Two Sigma Advisers's 13F filing for Q1 2025, filed 15 May 2025.