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Two Sigma Advisers Portfolio holdings
AUM
$51.4B
1-Year Est. Return
31.07%
This Fund
S&P 500
This Quarter
Est. Return
-3%
1 Year Est. Return
+31.07%
3 Year Est. Return
+128.94%
5 Year Est. Return
+161.75%
10 Year Est. Return
+607.04%
AUM
$44.4B
AUM Growth
+$1.2B
(+2.8%)
Cap. Flow
+$3.32B
Cap. Flow
% of AUM
7.48%
Top 10 Holdings %
Top 10 Hldgs %
17.65%
Holding
2,641
New
312
Increased
1,037
Reduced
994
Closed
281
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
Broadcom
AVGO
|
+$519M |
| 2 |
Salesforce
CRM
|
+$460M |
| 3 |
Regeneron Pharmaceuticals
REGN
|
+$381M |
| 4 |
Boston Scientific
BSX
|
+$347M |
| 5 |
Intuitive Surgical
ISRG
|
+$319M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Visa
V
|
+$555M |
| 2 |
Eli Lilly
LLY
|
+$536M |
| 3 |
Meta Platforms (Facebook)
META
|
+$433M |
| 4 |
Progressive
PGR
|
+$330M |
| 5 |
Lam Research
LRCX
|
+$294M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 25.86% |
| 2 | Healthcare | 15.38% |
| 3 | Financials | 14.3% |
| 4 | Consumer Discretionary | 11.43% |
| 5 | Industrials | 10.56% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
2476
Immatics
IMTX
$1.19B
| – | – |
-18,700
| Closed | -$133K |
|
2477
Immunic
IMUX
$182M
| – | – |
-1,072
| Closed | -$10.7K |
|
2478
Immunovant
IMVT
$7.99B
| – | – |
-10,900
| Closed | -$270K |
|
2479
Indivior Pharmaceuticals
INDV
$4.85B
| – | – |
-21,700
| Closed | -$270K |
|
2480
INmune Bio
INMB
$45.5M
| – | – |
-12,700
| Closed | -$59.3K |
|
2481
International Seaways
INSW
$4.63B
| – | – |
-22,773
| Closed | -$818K |
|
2482
Identive
INVE
$64.1M
| – | – |
-27,200
| Closed | -$99.6K |
|
2483
Invivyd
IVVD
$175M
| – | – |
-304,200
| Closed | -$135K |
|
2484
JD.com
JD
$42.9B
| – | – |
-1,486,600
| Closed | -$51.5M |
|
|
KALV
2485
DELISTED
KalVista Pharmaceuticals
KALV
| – | – |
-22,822
| Closed | -$193K |
|
2486
Keysight
KEYS
$52.2B
| – | – |
-18,300
| Closed | -$2.94M |
|
2487
Kodak
KODK
$812M
| – | – |
-12,700
| Closed | -$83.4K |
|
2488
Kopin
KOPN
$654M
| – | – |
-129,800
| Closed | -$177K |
|
2489
Karyopharm Therapeutics
KPTI
$161M
| – | – |
-5,107
| Closed | -$51.8K |
|
2490
KVH Industries
KVHI
$172M
| – | – |
-12,200
| Closed | -$69.5K |
|
2491
Quaker Houghton
KWR
$2.67B
| – | – |
-7,300
| Closed | -$1.03M |
|
2492
Loews
L
$24.6B
| – | – |
-14,400
| Closed | -$1.22M |
|
2493
Standard BioTools
LAB
$311M
| – | – |
-14,132
| Closed | -$24.7K |
|
2494
nLIGHT
LASR
$3.57B
| – | – |
-60,400
| Closed | -$634K |
|
2495
CS Disco
LAW
$270M
| – | – |
-17,300
| Closed | -$86.3K |
|
2496
Liberty Energy
LBRT
$2.89B
| – | – |
-139,700
| Closed | -$2.78M |
|
2497
loanDepot
LDI
$559M
| – | – |
-46,800
| Closed | -$95.5K |
|
2498
Lumentum
LITE
$50.7B
| – | – |
-243,600
| Closed | -$20.5M |
|
|
LSEA
2499
DELISTED
Landsea Homes
LSEA
| – | – |
-32,900
| Closed | -$279K |
|
2500
Lightspeed Commerce
LSPD
$1.41B
| – | – |
-64,800
| Closed | -$987K |
|
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VRS
FAF
BGIM
CIM
PPFA
Two Sigma Advisers's Q1 2025 Portfolio in Review
As of Q1 2025, Two Sigma Advisers held 2,641 positions worth $44.4B, up 2.8% from $43.2B the previous quarter. Its ten largest holdings account for 18% of the portfolio.
Two Sigma Advisers deployed $3.32B of net new capital in Q1 2025, opening 312 new positions and adding to 1,037 existing holdings. Its largest new stake was Regeneron Pharmaceuticals: 553,800 shares worth $351M.
By sector, the portfolio is most concentrated in Technology at 26% of assets, up from 25% a quarter earlier, followed by Healthcare and Financials.
On the sell side, the largest reduction was Visa, an estimated $555M trimmed.
- Two Sigma Advisers's largest Q1 2025 buy was Regeneron Pharmaceuticals: 553,800 shares worth $351M.
- Two Sigma Advisers added most to Broadcom in Q1 2025, an estimated $519M increase.
- Two Sigma Advisers's biggest Q1 2025 reduction was Visa, cutting an estimated $555M.
- Two Sigma Advisers fully exited Abbott in Q1 2025, selling an estimated $158M.
- Two Sigma Advisers's ten largest holdings make up 18% of its $44.4B portfolio in Q1 2025.
- Two Sigma Advisers opened 312 new positions and closed 281 in Q1 2025.
- Two Sigma Advisers's portfolio value rose 2.8% quarter-over-quarter to $44.4B.
Based on Two Sigma Advisers's 13F filing for Q1 2025, filed 15 May 2025.