TCM

Tekla Capital Management Portfolio holdings

AUM $2.56B
1-Year Return 18.15%
This Quarter Return
-2.75%
1 Year Return
+18.15%
3 Year Return
+62.34%
5 Year Return
+140.22%
10 Year Return
+499.57%
AUM
$2.85B
AUM Growth
-$260M
Cap. Flow
-$73M
Cap. Flow %
-2.56%
Top 10 Hldgs %
35.96%
Holding
185
New
14
Increased
26
Reduced
26
Closed
10

Top Buys

1
AZN icon
AstraZeneca
AZN
$13.5M
2
SYK icon
Stryker
SYK
$11.3M
3
VRTX icon
Vertex Pharmaceuticals
VRTX
$9.35M
4
XBI icon
SPDR S&P Biotech ETF
XBI
$8.6M
5
BDX icon
Becton Dickinson
BDX
$8.15M

Top Sells

1
MRNA icon
Moderna
MRNA
$37.6M
2
TMO icon
Thermo Fisher Scientific
TMO
$32.3M
3
MRK icon
Merck
MRK
$17.4M
4
ARNA
Arena Pharmaceuticals Inc
ARNA
$16.4M
5
DHR icon
Danaher
DHR
$15.3M

Sector Composition

1 Healthcare 95.64%
2 Real Estate 3.21%
3 Industrials 0.19%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
CCXI
126
DELISTED
ChemoCentryx, Inc.
CCXI
$1.96M 0.07%
78,197
– –
ZLAB icon
127
Zai Lab
ZLAB
$3.34B
$1.9M 0.07%
43,300
– –
FULC icon
128
Fulcrum Therapeutics
FULC
$372M
$1.83M 0.06%
77,293
– –
ACAD icon
129
Acadia Pharmaceuticals
ACAD
$4.3B
$1.75M 0.06%
72,225
– –
MREO
130
Mereo BioPharma
MREO
$275M
$1.74M 0.06%
1,551,082
– –
MEDP icon
131
Medpace
MEDP
$13.6B
$1.54M 0.05%
9,435
-9,436
-50% -$1.54M
STVN icon
132
Stevanato
STVN
$6.29B
$1.43M 0.05%
+71,190
New +$1.43M
MORF
133
DELISTED
Morphic Holding, Inc. Common Stock
MORF
$1.41M 0.05%
35,025
– –
SRRK icon
134
Scholar Rock
SRRK
$3.12B
$1.4M 0.05%
108,833
– –
ITOS
135
DELISTED
iTeos Therapeutics
ITOS
$1.36M 0.05%
42,362
– –
STRO icon
136
Sutro Biopharma
STRO
$86.5M
$1.35M 0.05%
163,924
-163,926
-50% -$1.35M
HARP
137
DELISTED
Harpoon Therapeutics, Inc. Common Stock
HARP
$1.29M 0.05%
+25,991
New +$1.29M
ACET icon
138
Adicet Bio
ACET
$59.4M
$1.27M 0.04%
63,329
– –
FATE icon
139
Fate Therapeutics
FATE
$112M
$1.23M 0.04%
31,652
-41,075
-56% -$1.59M
ASRT icon
140
Assertio
ASRT
$77.7M
$1.18M 0.04%
410,575
– –
THRX
141
DELISTED
Theseus Pharmaceuticals, Inc. Common Stock
THRX
$1.15M 0.04%
100,000
– –
DHC
142
Diversified Healthcare Trust
DHC
$939M
$1.15M 0.04%
357,720
– –
ENDP
143
DELISTED
Endo International plc
ENDP
$1.14M 0.04%
494,607
– –
ALXO icon
144
ALX Oncology
ALXO
$57.8M
$1.12M 0.04%
66,211
– –
DSGN icon
145
Design Therapeutics
DSGN
$348M
$1.06M 0.04%
65,351
– –
CYH icon
146
Community Health Systems
CYH
$398M
$1.05M 0.04%
88,335
– –
SNDX icon
147
Syndax Pharmaceuticals
SNDX
$1.39B
$982K 0.03%
+56,480
New +$982K
BEAM icon
148
Beam Therapeutics
BEAM
$1.88B
$906K 0.03%
15,817
– –
ICPT
149
DELISTED
Intercept Pharmaceuticals, Inc.
ICPT
$847K 0.03%
52,067
– –
RXDX
150
DELISTED
Prometheus Biosciences, Inc. Common Stock
RXDX
$835K 0.03%
+22,115
New +$835K
4 5
6
7 8