TCM

Tang Capital Management Portfolio holdings

AUM $1.81B

This Quarter Return

-5.03%

1 Year Return

-0.32%

3 Year Return

+265.66%

5 Year Return

+421.21%

10 Year Return

+1,438.57%

AUM

$1.81B

AUM Growth

+$296M (+20%)

Cap. Flow

+$415M

Cap. Flow % of AUM

22.93%

Top 10 Holdings %Top 10 Hldgs %

39.2%

Holding

208

New

Increased

Reduced

Closed

Top Buys

1	Dynavax Technologies DVAX	$50.6M
2	Galapagos GLPG	$45.2M
3	Kiniksa Pharmaceuticals KNSA	$33.1M
4	Spyre Therapeutics SYRE	$33.1M
5	SLRN ACELYRIN SLRN	$24.3M

Top Sells

1	ITCI Intra-Cellular Therapies Inc. ITCI	$10.6M
2	OMIC Singular Genomics Systems, Inc. Common Stock OMIC	$7.23M
3	GRAL GRAIL, Inc. Common Stock GRAL	$4.82M
4	ALMS Alumis Inc. Common Stock ALMS	$4.72M
5	KLRS Kalaris Therapeutics, Inc. Common Stock KLRS	$1.95M

Sector Composition

1	Healthcare	94.79%
2	Technology	1.25%
3	Communication Services	1.23%
4	Consumer Discretionary	0.99%
5	Financials	0.57%

#	Name	Market Value	Portfolio Weight	Shares or Principal	Shares Change %	Capital Flow
26	26 AstraZeneca AZN $213B	$18.4M	1.02%	250,000 +100,000	+67%	+$7.35M
27	27 Liquidia Corp LQDA $1.24B	$17.7M	0.98%	1,200,000 +100,000	+9%	+$1.48M
28	28 Neurocrine Biosciences NBIX $13.1B	$16.6M	0.92%	150,000	–	–
29	AVDL 29 Avadel Pharmaceuticals AVDL $1.05B	$16.4M	0.91%	2,097,500 +600,000	+40%	+$4.7M
30	30 iTeos Therapeutics ITOS $393M	$16.1M	0.89%	2,689,200 +2,467,484	+1,113%	+$14.7M
31	31 Meta Platforms (Facebook) META $1.77T	$15.9M	0.88%	27,575 +975	+4%	+$562K
32	32 GSK GSK $73.3B	$15.5M	0.86%	400,000	–	–
33	33 NVIDIA NVDA $4.2T	$15.5M	0.85%	142,569	–	–
34	34 Sanofi SNY $118B	$15M	0.83%	270,000	–	–
35	35 Atea Pharmaceuticals AVIR $288M	$14.4M	0.79%	4,800,000 +11,088	+0.2%	+$33.2K
36	36 Altimmune ALT $331M	$13.8M	0.76%	2,750,000	–	–
37	37 Zymeworks ZYME $1.07B	$13.1M	0.72%	1,100,000	–	–
38	38 Nkarta NKTX $136M	$13M	0.72%	7,055,576 +4,761,857	+208%	+$8.76M
39	39 CARGO Therapeutics CRGX $213M	$12.5M	0.69%	3,059,630 +2,419,630	+378%	+$9.85M
40	CYBN 40 Cybin CYBN $192M	$11.6M	0.64%	1,830,097 +500,000	+38%	+$3.17M
41	41 Vaxcyte PCVX $4.67B	$11.3M	0.63%	300,000	–	–
42	42 Keros Therapeutics KROS $558M	$11.2M	0.62%	+1,100,000	New	+$11.2M
43	43 Teladoc Health TDOC $1.41B	$11.1M	0.62%	1,400,000	–	–
44	44 Journey Medical DERM $167M	$10.9M	0.61%	1,854,596 +129,027	+7%	+$761K
45	45 Vanda Pharmaceuticals VNDA $282M	$10.8M	0.6%	2,353,307	–	–
46	ONC 46 BeOne Medicines Ltd. American Depositary Shares ONC $31.9B	$10.1M	0.56%	37,000	–	–
47	47 Arvinas ARVN $536M	$9.78M	0.54%	+1,393,800	New	+$9.78M
48	48 Harmony Biosciences HRMY $2.02B	$9.33M	0.52%	281,200	–	–
49	49 Alibaba BABA $287B	$9.26M	0.51%	+70,000	New	+$9.26M
50	50 CRISPR Therapeutics CRSP $5.62B	$9.07M	0.5%	266,500	–	–