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Soleus Capital Management Portfolio holdings

AUM $2.47B
1-Year Est. Return 115.63%
This Fund
S&P 500
This Quarter Est. Return
+5.31%
1 Year Est. Return
+115.63%
3 Year Est. Return
+435.52%
5 Year Est. Return
+604.31%
10 Year Est. Return
AUM
$999M
AUM Growth
+$357M
Cap. Flow
+$419M
Cap. Flow %
41.94%
Top 10 Hldgs %
54.5%
Holding
94
New
23
Increased
23
Reduced
18
Closed
26

Sector Composition

Rank Sector Weight
1 Healthcare 70.82%
2 Financials 0.64%
3 Consumer Staples 0%
4 Real Estate 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
PVLA
51
Palvella Therapeutics
PVLA
$2.19B
$2.6M 0.26%
8,593
-657
-7% -$210K
VNDA icon
52
Vanda Pharmaceuticals
VNDA
$312M
$2.49M 0.25%
158,700
-139,900
-47% -$2.44M
CCXI
53
DELISTED
ChemoCentryx, Inc.
CCXI
$2.49M 0.25%
+68,320
New +$2.4M
VRDN icon
54
Viridian Therapeutics
VRDN
$2.43B
$1.78M 0.18%
+90,000
New +$1.68M
IMUX icon
55
Immunic
IMUX
$194M
$1.68M 0.17%
+17,500
New +$1.58M
NVCR icon
56
NovoCure
NVCR
$1.84B
$1.67M 0.17%
22,275
-5,000
-18% -$502K
CRSP icon
57
CRISPR Therapeutics
CRSP
$5.05B
$1.67M 0.17%
22,000
-70,214
-76% -$6.13M
AVTX icon
58
Avalo Therapeutics
AVTX
$973M
$1.31M 0.13%
+267
New +$1.6M
LQDA icon
59
Liquidia Corp
LQDA
$7.93B
$1.13M 0.11%
+231,485
New +$923K
ARVN icon
60
Arvinas
ARVN
$554M
$904K 0.09%
+11,000
New +$895K
HOWL icon
61
Werewolf Therapeutics
HOWL
$19.5M
$769K 0.08%
64,585
-498,811
-89% -$7.53M
BCYC
62
Bicycle Therapeutics
BCYC
$276M
$624K 0.06%
+10,250
New +$566K
FATE icon
63
Fate Therapeutics
FATE
$288M
$456K 0.05%
+7,800
New +$442K
CELC icon
64
Celcuity
CELC
$4.51B
$423K 0.04%
32,073
-51,615
-62% -$826K
NGM
65
DELISTED
NGM Biopharmaceuticals, Inc. Common Stock
NGM
$230K 0.02%
13,000
-28,000
-68% -$537K
BEAM icon
66
Beam Therapeutics
BEAM
$2.83B
$227K 0.02%
2,850
-4,850
-63% -$415K
LYRA
67
DELISTED
LYRA THERAPEUTICS INC
LYRA
$44K ﹤0.01%
200
-4,112
-95% -$1.32M
ASMB icon
68
Assembly Biosciences
ASMB
$525M
-93,500
Closed -$3.9M
ATXS
69
DELISTED
Astria Therapeutics
ATXS
-112,499
Closed -$994K
AVIR icon
70
Atea Pharmaceuticals
AVIR
$389M
-117,600
Closed -$4.12M
AXGN icon
71
Axogen
AXGN
$2.39B
-158,140
Closed -$2.5M
CDNA icon
72
CareDx
CDNA
$2.35B
-126,661
Closed -$8.03M
CMPS
73
Compass Pathways
CMPS
$1.82B
-127,743
Closed -$3.82M
CORT icon
74
Corcept Therapeutics
CORT
$11.7B
-155,000
Closed -$3.05M
CTMX icon
75
CytomX Therapeutics
CTMX
$736M
-261,050
Closed -$1.33M

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Soleus Capital Management's Q4 2021 Portfolio in Review

As of Q4 2021, Soleus Capital Management held 94 positions worth $999M, up 56% from $642M the previous quarter. Its ten largest holdings account for 54% of the portfolio.

Soleus Capital Management deployed $419M of net new capital in Q4 2021, opening 23 new positions and adding to 23 existing holdings. Its largest new stake was Smith & Nephew: 593,200 shares worth $20.5M.

By sector, the portfolio is most concentrated in Healthcare at 71% of assets, down from 92% a quarter earlier, followed by Financials and Consumer Staples.

On the sell side, the largest reduction was Werewolf Therapeutics, an estimated $7.53M trimmed.

  • Soleus Capital Management's largest Q4 2021 buy was Smith & Nephew: 593,200 shares worth $20.5M.
  • Soleus Capital Management added most to Nurix Therapeutics in Q4 2021, an estimated $14.5M increase.
  • Soleus Capital Management's biggest Q4 2021 reduction was Werewolf Therapeutics, cutting an estimated $7.53M.
  • Soleus Capital Management fully exited Flexion Therapeutics, Inc. in Q4 2021, selling an estimated $12.7M.
  • Soleus Capital Management's ten largest holdings make up 54% of its $999M portfolio in Q4 2021.
  • Soleus Capital Management opened 23 new positions and closed 26 in Q4 2021.
  • Soleus Capital Management's portfolio value rose 56% quarter-over-quarter to $999M.

Based on Soleus Capital Management's 13F filing for Q4 2021, filed 14 Feb 2022.