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Samsara BioCapital Portfolio holdings

AUM $1.03B
1-Year Est. Return 214.94%
This Fund
S&P 500
This Quarter Est. Return
+16.16%
1 Year Est. Return
+214.94%
3 Year Est. Return
+1,814.37%
5 Year Est. Return
+1,842.35%
10 Year Est. Return
AUM
$1.03B
AUM Growth
+$59.8M
Cap. Flow
+$91.1M
Cap. Flow %
8.85%
Top 10 Hldgs %
91.97%
Holding
24
New
3
Increased
2
Reduced
3
Closed
2

Sector Composition

Rank Sector Weight
1 Healthcare 100%

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Samsara BioCapital's Q1 2026 Portfolio in Review

As of Q1 2026, Samsara BioCapital held 24 positions worth $1.03B, up 6.2% from $969M the previous quarter. Its ten largest holdings account for 92% of the portfolio.

Samsara BioCapital deployed $91.1M of net new capital in Q1 2026, opening 3 new positions and adding to 2 existing holdings. Its largest new stake was SpyGlass Pharma: 2,109,953 shares worth $54.7M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, up from 100% a quarter earlier.

On the sell side, the largest reduction was Palvella Therapeutics, an estimated $6.92M trimmed.

  • Samsara BioCapital's largest Q1 2026 buy was SpyGlass Pharma: 2,109,953 shares worth $54.7M.
  • Samsara BioCapital added most to Sutro Biopharma in Q1 2026, an estimated $15.5M increase.
  • Samsara BioCapital's biggest Q1 2026 reduction was Palvella Therapeutics, cutting an estimated $6.92M.
  • Samsara BioCapital fully exited Contineum Therapeutics in Q1 2026, selling an estimated $826K.
  • Samsara BioCapital's ten largest holdings make up 92% of its $1.03B portfolio in Q1 2026.
  • Samsara BioCapital opened 3 new positions and closed 2 in Q1 2026.
  • Samsara BioCapital's portfolio value rose 6.2% quarter-over-quarter to $1.03B.

Based on Samsara BioCapital's 13F filing for Q1 2026, filed 15 May 2026.