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Rock Springs Capital Management Portfolio holdings

AUM $1.7B
1-Year Est. Return 93.03%
This Fund
S&P 500
This Quarter Est. Return
-1.43%
1 Year Est. Return
+93.03%
3 Year Est. Return
+228.43%
5 Year Est. Return
+368.14%
10 Year Est. Return
+4,607.77%
AUM
$1.75B
AUM Growth
-$879M
Cap. Flow
-$770M
Cap. Flow %
-44.05%
Top 10 Hldgs %
36.57%
Holding
112
New
6
Increased
25
Reduced
47
Closed
16

Top Buys

Rank Stock Value
1
DHR icon
Danaher
DHR
+$12.8M
2
TARS icon
Tarsus Pharmaceuticals
TARS
+$12M
3
EVH icon
Evolent Health
EVH
+$6.42M
4
MRUS
Merus
MRUS
+$3.85M
5
ACHC icon
Acadia Healthcare
ACHC
+$3.72M

Top Sells

Rank Stock Value
1
ISRG icon
Intuitive Surgical
ISRG
+$63M
2
NBIX icon
Neurocrine Biosciences
NBIX
+$55.9M
3
FRPT icon
Freshpet
FRPT
+$48.5M
4
TVTX icon
Travere Therapeutics
TVTX
+$41.7M
5
UNH icon
UnitedHealth
UNH
+$38.6M

Sector Composition

Rank Sector Weight
1 Healthcare 99.7%
2 Consumer Staples 0%
3 Financials 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
CRNX icon
101
Crinetics Pharmaceuticals
CRNX
$8.94B
– –
-294,100
Closed -$15M
FRPT icon
102
Freshpet
FRPT
$3.4B
– –
-327,500
Closed -$48.5M
LFST icon
103
Lifestance Health
LFST
$4.47B
– –
-2,550,000
Closed -$18.8M
CYPH
104
Cypherpunk Technologies Inc
CYPH
$72.1M
– –
-1,266,546
Closed -$3.64M
NMRA icon
105
Neumora Therapeutics
NMRA
$308M
– –
-955,106
Closed -$10.1M
PODD icon
106
Insulet
PODD
$10B
– –
-114,250
Closed -$29.8M
SWTX
107
DELISTED
SpringWorks Therapeutics
SWTX
– –
-328,911
Closed -$11.9M
XLO icon
108
Xilio Therapeutics
XLO
$60.4M
– –
-214,519
Closed -$2.87M
XNCR icon
109
Xencor
XNCR
$1.63B
– –
-401,013
Closed -$9.22M
KYTX icon
110
Kyverna Therapeutics
KYTX
$485M
– –
-178,963
Closed -$669K
VINC
111
DELISTED
Vincerx Pharma, Inc. Common Stock
VINC
– –
-44,586
Closed -$234K
1 2 3 4
5

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Rock Springs Capital Management's Q1 2025 Portfolio in Review

As of Q1 2025, Rock Springs Capital Management held 112 positions worth $1.75B, down 33% from $2.63B the previous quarter. Its ten largest holdings account for 37% of the portfolio.

Rock Springs Capital Management withdrew a net $770M in Q1 2025, closing 16 positions and reducing 47 holdings. Its most notable exit was Freshpet, an estimated $48.5M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, up from 98% a quarter earlier, followed by Consumer Staples and Financials.

Against the trend, Rock Springs Capital Management opened a new position in Danaher worth $12.1M.

  • Rock Springs Capital Management's largest Q1 2025 buy was Danaher: 58,800 shares worth $12.1M.
  • Rock Springs Capital Management added most to Tarsus Pharmaceuticals in Q1 2025, an estimated $12M increase.
  • Rock Springs Capital Management's biggest Q1 2025 reduction was Intuitive Surgical, cutting an estimated $63M.
  • Rock Springs Capital Management fully exited Freshpet in Q1 2025, selling an estimated $48.5M.
  • Rock Springs Capital Management's ten largest holdings make up 37% of its $1.75B portfolio in Q1 2025.
  • Rock Springs Capital Management opened 6 new positions and closed 16 in Q1 2025.
  • Rock Springs Capital Management's portfolio value fell 33% quarter-over-quarter to $1.75B.

Based on Rock Springs Capital Management's 13F filing for Q1 2025, filed 15 May 2025.