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Rock Springs Capital Management Portfolio holdings

AUM $1.7B
1-Year Est. Return 93.03%
This Fund
S&P 500
This Quarter Est. Return
+5.31%
1 Year Est. Return
+93.03%
3 Year Est. Return
+228.43%
5 Year Est. Return
+368.14%
10 Year Est. Return
+4,607.77%
AUM
$2.63B
AUM Growth
-$447M
Cap. Flow
-$292M
Cap. Flow %
-11.12%
Top 10 Hldgs %
36.37%
Holding
119
New
10
Increased
38
Reduced
30
Closed
12

Top Sells

Rank Stock Value
1
UNH icon
UnitedHealth
UNH
+$67.2M
2
HUM icon
Humana
HUM
+$46.9M
3
EXAS
Exact Sciences
EXAS
+$43.4M
4
ALGN icon
Align Technology
ALGN
+$29.1M
5
ISRG icon
Intuitive Surgical
ISRG
+$28.1M

Sector Composition

Rank Sector Weight
1 Healthcare 97.8%
2 Consumer Staples 1.85%
3 Financials 0.14%
4 Industrials 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
BMEA icon
101
Biomea Fusion
BMEA
$92.1M
$703K 0.03%
181,147
KYTX icon
102
Kyverna Therapeutics
KYTX
$480M
$669K 0.03%
178,963
VINC
103
DELISTED
Vincerx Pharma, Inc. Common Stock
VINC
$234K 0.01%
44,586
TLPH icon
104
Talphera
TLPH
$73.2M
$166K 0.01%
316,460
NUVB.WS
105
DELISTED
Nuvation Bio Inc Warrants
NUVB.WS
$30.8K ﹤0.01%
134,028
ALGN icon
106
Align Technology
ALGN
$12.5B
-114,500
Closed -$29.1M
AUPH icon
107
Aurinia Pharmaceuticals
AUPH
$2.06B
-1,179,740
Closed -$8.65M
BMRN icon
108
BioMarin Pharmaceuticals
BMRN
$13.3B
-151,000
Closed -$10.6M
CYTK icon
109
Cytokinetics
CYTK
$10.5B
-206,108
Closed -$10.9M
DVAX
110
DELISTED
Dynavax Technologies
DVAX
-605,013
Closed -$6.74M
EPIX
111
DELISTED
ESSA Pharma
EPIX
-677,005
Closed -$4.1M
HUM icon
112
Humana
HUM
$46.3B
-148,000
Closed -$46.9M
JNJ icon
113
Johnson & Johnson
JNJ
$631B
-80,000
Closed -$13M
KRYS icon
114
Krystal Biotech
KRYS
$9.81B
-55,861
Closed -$10.2M
NVO
115
Novo Nordisk
NVO
$211B
-132,000
Closed -$15.7M
PCRX icon
116
Pacira BioSciences
PCRX
$974M
-400,000
Closed -$6.02M
ACCD
117
DELISTED
Accolade Inc
ACCD
-160,217
Closed -$617K

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Rock Springs Capital Management's Q4 2024 Portfolio in Review

As of Q4 2024, Rock Springs Capital Management held 119 positions worth $2.63B, down 15% from $3.07B the previous quarter. Its ten largest holdings account for 36% of the portfolio.

Rock Springs Capital Management withdrew a net $292M in Q4 2024, closing 12 positions and reducing 30 holdings. Its most notable exit was Humana, an estimated $46.9M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 98% of assets, up from 98% a quarter earlier, followed by Consumer Staples and Financials.

Against the trend, Rock Springs Capital Management opened a new position in Scholar Rock worth $31M.

  • Rock Springs Capital Management's largest Q4 2024 buy was Scholar Rock: 716,782 shares worth $31M.
  • Rock Springs Capital Management added most to Blueprint Medicines in Q4 2024, an estimated $30.1M increase.
  • Rock Springs Capital Management's biggest Q4 2024 reduction was UnitedHealth, cutting an estimated $67.2M.
  • Rock Springs Capital Management fully exited Humana in Q4 2024, selling an estimated $46.9M.
  • Rock Springs Capital Management's ten largest holdings make up 36% of its $2.63B portfolio in Q4 2024.
  • Rock Springs Capital Management opened 10 new positions and closed 12 in Q4 2024.
  • Rock Springs Capital Management's portfolio value fell 15% quarter-over-quarter to $2.63B.

Based on Rock Springs Capital Management's 13F filing for Q4 2024, filed 14 Feb 2025.