RA Capital Management Portfolio holdings
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
SGP
SpyGlass Pharma
SGP
|
+$216M |
| 2 |
Wave Life Sciences
WVE
|
+$114M |
| 3 |
Zai Lab
ZLAB
|
+$106M |
| 4 |
Sarepta Therapeutics
SRPT
|
+$75.5M |
| 5 |
NUVL
Nuvalent
NUVL
|
+$66.7M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
CDTX
Cidara Therapeutics
CDTX
|
+$743M |
| 2 |
RNAM
Avidity Biosciences
RNAM
|
+$623M |
| 3 |
ACLX
Arcellx
ACLX
|
+$82.6M |
| 4 |
BLTE
Belite Bio
BLTE
|
+$69.2M |
| 5 |
Invivyd
IVVD
|
+$42.3M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Healthcare | 99.71% |
| 2 | Financials | 0.22% |
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RA Capital Management's Q1 2026 Portfolio in Review
As of Q1 2026, RA Capital Management held 95 positions worth $9.44B, down 3.3% from $9.76B the previous quarter. Its ten largest holdings account for 61% of the portfolio.
RA Capital Management withdrew a net $311M in Q1 2026, closing 10 positions and reducing 2 holdings. Its most notable exit was Cidara Therapeutics, an estimated $743M position sold in full.
By sector, the portfolio is most concentrated in Healthcare at 100% of assets, down from 100% a quarter earlier, followed by Financials.
Against the trend, RA Capital Management opened a new position in SpyGlass Pharma worth $208M.
- RA Capital Management's largest Q1 2026 buy was SpyGlass Pharma: 8,021,117 shares worth $208M.
- RA Capital Management added most to Wave Life Sciences in Q1 2026, an estimated $114M increase.
- RA Capital Management's biggest Q1 2026 reduction was Contineum Therapeutics, cutting an estimated $11.9M.
- RA Capital Management fully exited Cidara Therapeutics in Q1 2026, selling an estimated $743M.
- RA Capital Management's ten largest holdings make up 61% of its $9.44B portfolio in Q1 2026.
- RA Capital Management opened 24 new positions and closed 10 in Q1 2026.
- RA Capital Management's portfolio value fell 3.3% quarter-over-quarter to $9.44B.
Based on RA Capital Management's 13F filing for Q1 2026, filed 15 May 2026.