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Perceptive Advisors Portfolio holdings

AUM $5.12B
1-Year Est. Return 314.02%
This Fund
S&P 500
This Quarter Est. Return
+57.75%
1 Year Est. Return
+314.02%
3 Year Est. Return
+1,498.66%
5 Year Est. Return
+2,457.67%
10 Year Est. Return
+48,821.41%
AUM
$4.48B
AUM Growth
+$1.48B
Cap. Flow
+$437M
Cap. Flow %
9.75%
Top 10 Hldgs %
48.38%
Holding
120
New
23
Increased
28
Reduced
22
Closed
19

Top Buys

Rank Stock Value
1
CRGX
CARGO Therapeutics
CRGX
+$58.3M
2
RYTM icon
Rhythm Pharmaceuticals
RYTM
+$55.9M
3
AXSM icon
Axsome Therapeutics
AXSM
+$37.2M
4
SYRE icon
Spyre Therapeutics
SYRE
+$34.8M
5
ABBV icon
AbbVie
ABBV
+$34.7M

Top Sells

Rank Stock Value
1
ARGX icon
argenx
ARGX
+$74M
2
IMVT icon
Immunovant
IMVT
+$54.7M
3
ROIV icon
Roivant Sciences
ROIV
+$44.6M
4
HRMY icon
Harmony Biosciences
HRMY
+$32.6M
5
RLAY icon
Relay Therapeutics
RLAY
+$16.3M

Sector Composition

Rank Sector Weight
1 Healthcare 99.85%
2 Financials 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
CMAXW
101
DELISTED
CareMax, Inc. Warrant
CMAXW
$450 ﹤0.01%
60,000
– –
ACRS icon
102
PUT
Aclaris Therapeutics
ACRS
$715M
– –
-500,000
Closed -$1.45M
AKRO
103
CALL
DELISTED
Akero Therapeutics
AKRO
– –
-800,000
Closed -$5.46M
APLS
104
PUT
DELISTED
Apellis Pharmaceuticals
APLS
– –
-100,000
Closed -$72.5K
ARGX icon
105
argenx
ARGX
$55.2B
– –
-150,600
Closed -$74M
ARQT icon
106
PUT
Arcutis Biotherapeutics
ARQT
$3.48B
– –
-300,000
Closed -$2.62M
BMEA icon
107
Biomea Fusion
BMEA
$88.2M
– –
-716,441
Closed -$9.86M
ETNB
108
CALL
DELISTED
89bio
ETNB
– –
-400,000
Closed -$1.62M
HRMY icon
109
Harmony Biosciences
HRMY
$2.08B
– –
-996,306
Closed -$32.6M
OM icon
110
Outset Medical
OM
$86.4M
– –
-44,132
Closed -$7.2M
PRTA icon
111
Prothena Corp
PRTA
$448M
– –
-165,615
Closed -$7.99M
RLAY icon
112
Relay Therapeutics
RLAY
$4B
– –
-1,943,097
Closed -$16.3M
ROIV icon
113
Roivant Sciences
ROIV
$23.6B
– –
-3,819,456
Closed -$44.6M
SLRN
114
DELISTED
ACELYRIN
SLRN
– –
-200,000
Closed -$2.03M
SRPT icon
115
CALL
Sarepta Therapeutics
SRPT
$1.64B
– –
-100,000
Closed -$3.13M
VKTX icon
116
CALL
Viking Therapeutics
VKTX
$3.88B
– –
-300,000
Closed -$240K
MOTS
117
DELISTED
Motus GI Holdings, Inc. Common Stock
MOTS
– –
-6,002
Closed -$40.5K
SLGC
118
DELISTED
SomaLogic, Inc. Class A Common Stock
SLGC
– –
-1,500,000
Closed -$3.58M
PNT
119
PUT
DELISTED
POINT Biopharma Global Inc. Common Stock
PNT
– –
-800,000
Closed -$2.63M
EQRXW
120
DELISTED
EQRx, Inc. Warrant
EQRXW
– –
-250,000
Closed -$10K
1 2 3 4
5

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Perceptive Advisors's Q4 2023 Portfolio in Review

As of Q4 2023, Perceptive Advisors held 120 positions worth $4.48B, up 49% from $3B the previous quarter. Its ten largest holdings account for 48% of the portfolio.

Perceptive Advisors deployed $437M of net new capital in Q4 2023, opening 23 new positions and adding to 28 existing holdings. Its largest new stake was CARGO Therapeutics: 3,436,600 shares worth $79.6M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, up from 99% a quarter earlier, followed by Financials.

On the sell side, the largest reduction was Immunovant, an estimated $54.7M trimmed.

  • Perceptive Advisors's largest Q4 2023 buy was CARGO Therapeutics: 3,436,600 shares worth $79.6M.
  • Perceptive Advisors added most to Rhythm Pharmaceuticals in Q4 2023, an estimated $55.9M increase.
  • Perceptive Advisors's biggest Q4 2023 reduction was Immunovant, cutting an estimated $54.7M.
  • Perceptive Advisors fully exited argenx in Q4 2023, selling an estimated $74M.
  • Perceptive Advisors's ten largest holdings make up 48% of its $4.48B portfolio in Q4 2023.
  • Perceptive Advisors opened 23 new positions and closed 19 in Q4 2023.
  • Perceptive Advisors's portfolio value rose 49% quarter-over-quarter to $4.48B.

Based on Perceptive Advisors's 13F filing for Q4 2023, filed 14 Feb 2024.