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Perceptive Advisors Portfolio holdings

AUM $6.66B
1-Year Est. Return 360.84%
This Fund
S&P 500
This Quarter Est. Return
-21.79%
1 Year Est. Return
+360.84%
3 Year Est. Return
+1,707.27%
5 Year Est. Return
+3,210.42%
10 Year Est. Return
+53,055.89%
AUM
$2.63B
AUM Growth
-$1.11B
Cap. Flow
-$123M
Cap. Flow %
-4.66%
Top 10 Hldgs %
51.48%
Holding
146
New
29
Increased
20
Reduced
29
Closed
45

Sector Composition

Rank Sector Weight
1 Healthcare 97.94%
2 Miscellaneous 1.24%
3 Consumer Staples 0.68%
4 Financials 0.08%
5 Consumer Discretionary 0.06%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
EIDX
51
DELISTED
Eidos Therapeutics, Inc. Common Stock
EIDX
$9.45M 0.36%
686,922
AKBA icon
52
Akebia Therapeutics
AKBA
$250M
$9.18M 0.35%
1,703,440
-746,081
-30% -$5.84M
ORTX
53
DELISTED
Orchard Therapeutics plc American Depositary Shares
ORTX
$8.21M 0.31%
+52,180
New +$7.78M
COLL icon
54
Collegium Pharmaceutical
COLL
$711M
$7.37M 0.28%
+445,000
New +$7.61M
ZYME icon
55
Zymeworks
ZYME
$1.86B
$7.2M 0.27%
573,890
-550,000
-49% -$7.22M
MTEM
56
DELISTED
Molecular Templates, Inc.
MTEM
$7.11M 0.27%
131,609
XNCR icon
57
Xencor
XNCR
$1.77B
$6.83M 0.26%
196,810
-631,285
-76% -$23.2M
SYBX
58
DELISTED
Synlogic
SYBX
$6.05M 0.23%
57,857
-5,000
-8% -$658K
QURE icon
59
uniQure
QURE
$2.99B
$5.95M 0.23%
220,707
-752,124
-77% -$20.9M
TXMD icon
60
TherapeuticsMD
TXMD
$25M
$5.71M 0.22%
30,000
DBVT
61
DBV Technologies
DBVT
$739M
$5.31M 0.2%
82,696
-218,304
-73% -$35.1M
MRTX
62
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$5.25M 0.2%
+125,875
New +$5.02M
UROV
63
DELISTED
Urovant Sciences Ltd.
UROV
$3.92M 0.15%
625,359
+162,700
+35% +$1.48M
ARWR icon
64
Arrowhead Research
ARWR
$9.98B
$3.58M 0.14%
300,000
-65,445
-18% -$895K
RCKT icon
65
Rocket Pharmaceuticals
RCKT
$374M
$3.5M 0.13%
+240,173
New +$3.99M
SRRA
66
DELISTED
Sierra Oncology, Inc. Common Stock
SRRA
$3.41M 0.13%
66,655
-13,345
-17% -$852K
TBIO
67
DELISTED
Translate Bio, Inc. Common Stock
TBIO
$3.17M 0.12%
435,000
-65,000
-13% -$476K
TDOC icon
68
Teladoc Health
TDOC
$1.2B
$2.97M 0.11%
+60,000
New +$3.67M
WVE icon
69
Wave Life Sciences
WVE
$879M
$2.5M 0.1%
59,498
-174,521
-75% -$7.76M
EHTH icon
70
eHealth
EHTH
$28.5M
$2.11M 0.08%
55,021
-171,199
-76% -$5.76M
PEN icon
71
Penumbra
PEN
$12.5B
$2.04M 0.08%
+16,338
New +$2.19M
VERU icon
72
Veru
VERU
$39.9M
$1.85M 0.07%
142,500
GRCE
73
Grace Therapeutics
GRCE
$46.9M
$1.48M 0.06%
+37,081
New +$1.62M
EIGR
74
DELISTED
Eiger BioPharmaceuticals, Inc.
EIGR
$1.42M 0.05%
4,663
-593
-11% -$192K
OMED
75
DELISTED
OncoMed Pharmaceuticals, Inc.
OMED
$1.28M 0.05%
1,719,111
-901,786
-34% -$1.36M

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Perceptive Advisors's Q4 2018 Portfolio in Review

As of Q4 2018, Perceptive Advisors held 146 positions worth $2.63B, down 30% from $3.74B the previous quarter. Its ten largest holdings account for 51% of the portfolio.

Perceptive Advisors withdrew a net $123M in Q4 2018, closing 45 positions and reducing 29 holdings. Its most notable exit was Corium International, Inc., an estimated $60.5M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 98% of assets, up from 93% a quarter earlier, followed by Miscellaneous and Consumer Staples.

Against the trend, Perceptive Advisors opened a new position in Solid Biosciences worth $105M.

  • Perceptive Advisors's largest Q4 2018 buy was Solid Biosciences: 261,815 shares worth $105M.
  • Perceptive Advisors added most to Amarin Corp in Q4 2018, an estimated $77.8M increase.
  • Perceptive Advisors's biggest Q4 2018 reduction was Alnylam Pharmaceuticals, cutting an estimated $72M.
  • Perceptive Advisors fully exited Corium International, Inc. in Q4 2018, selling an estimated $60.5M.
  • Perceptive Advisors's ten largest holdings make up 51% of its $2.63B portfolio in Q4 2018.
  • Perceptive Advisors opened 29 new positions and closed 45 in Q4 2018.
  • Perceptive Advisors's portfolio value fell 30% quarter-over-quarter to $2.63B.

Based on Perceptive Advisors's 13F filing for Q4 2018, filed 14 Feb 2019.