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KCM

Knoll Capital Management Portfolio holdings

AUM $180M
1-Year Est. Return 66.11%
This Fund
S&P 500
This Quarter Est. Return
+16.27%
1 Year Est. Return
+66.11%
3 Year Est. Return
+268.55%
5 Year Est. Return
+741%
10 Year Est. Return
+10,877.35%
AUM
$218M
AUM Growth
+$31.4M
Cap. Flow
+$20.5M
Cap. Flow %
9.41%
Top 10 Hldgs %
67.74%
Holding
39
New
1
Increased
4
Reduced
1
Closed
6

Top Sells

Rank Stock Value
1
SAND
Sandstorm Gold
SAND
+$8.76M
2
V icon
Visa
V
+$1.66M
3
APLT
Applied Therapeutics
APLT
+$1.11M
4
DEO icon
Diageo
DEO
+$644K
5
MREO
Mereo BioPharma
MREO
+$537K

Sector Composition

Rank Sector Weight
1 Healthcare 55.34%
2 Materials 33.92%
3 Industrials 1.07%
4 Consumer Staples 0.74%
5 Financials 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
WPM icon
26
Wheaton Precious Metals
WPM
$60.9B
$1.47M 0.67%
12,500
ABEO icon
27
Abeona Therapeutics
ABEO
$413M
$1.24M 0.57%
235,953
+173,264
+276% +$872K
NOC icon
28
Northrop Grumman
NOC
$81.2B
$1.23M 0.57%
2,165
BAH icon
29
Booz Allen Hamilton
BAH
$9.15B
$1.1M 0.5%
13,000
DC icon
30
Dakota Gold
DC
$804M
$698K 0.32%
122,921
APLT
31
DELISTED
Applied Therapeutics
APLT
$605K 0.28%
6,050,000
-1,749,687
-22% -$1.11M
CRDL
32
Cardiol Therapeutics
CRDL
$164M
$95.3K 0.04%
100,000
DEO icon
33
Diageo
DEO
$53.6B
-6,750
Closed -$644K
HOOK
34
DELISTED
HOOKIPA Pharma
HOOK
-498,625
Closed -$461K
MREO
35
Mereo BioPharma
MREO
$47.3M
-260,470
Closed -$537K
OBIO icon
36
Orchestra BioMed
OBIO
$254M
-455,128
Closed -$421K
SAND
37
DELISTED
Sandstorm Gold
SAND
-700,000
Closed -$8.76M
V icon
38
Visa
V
$677B
-4,850
Closed -$1.66M

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Knoll Capital Management's Q4 2025 Portfolio in Review

As of Q4 2025, Knoll Capital Management held 39 positions worth $218M, up 17% from $187M the previous quarter. Its ten largest holdings account for 68% of the portfolio.

Knoll Capital Management deployed $20.5M of net new capital in Q4 2025, opening 1 new position and adding to 4 existing holdings. Its largest new stake was SSR Mining: 245,000 shares worth $5.37M.

By sector, the portfolio is most concentrated in Healthcare at 55% of assets, up from 55% a quarter earlier, followed by Materials and Industrials.

On the sell side, the largest reduction was Applied Therapeutics, an estimated $1.11M trimmed.

  • Knoll Capital Management's largest Q4 2025 buy was SSR Mining: 245,000 shares worth $5.37M.
  • Knoll Capital Management added most to Biohaven Pharmaceutical Holding Company Ltd. in Q4 2025, an estimated $16.2M increase.
  • Knoll Capital Management's biggest Q4 2025 reduction was Applied Therapeutics, cutting an estimated $1.11M.
  • Knoll Capital Management fully exited Sandstorm Gold in Q4 2025, selling an estimated $8.76M.
  • Knoll Capital Management's ten largest holdings make up 68% of its $218M portfolio in Q4 2025.
  • Knoll Capital Management opened 1 new position and closed 6 in Q4 2025.
  • Knoll Capital Management's portfolio value rose 17% quarter-over-quarter to $218M.

Based on Knoll Capital Management's 13F filing for Q4 2025, filed 17 Feb 2026.