John Overdeck Two Sigma Investments
John Overdeck is a co-founder of Two Sigma Investments, one of the world’s leading quantitative and technology-driven investment firms. Two Sigma applies data science, machine learning, and large-scale computing to markets across asset classes. Overdeck’s firm is a central reference point in discussions of modern systematic investing.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street Financial Select Sector SPDR ETF
XLF
|
+$474M |
| 2 |
State Street Consumer Staples Select Sector SPDR ETF
XLP
|
+$357M |
| 3 |
Accenture
ACN
|
+$246M |
| 4 |
Advanced Micro Devices
AMD
|
+$235M |
| 5 |
State Street SPDR Dow Jones Industrial Average ETF Trust
DIA
|
+$231M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Invesco QQQ Trust
QQQ
|
+$381M |
| 2 |
State Street Technology Select Sector SPDR ETF
XLK
|
+$375M |
| 3 |
iShares Expanded Tech-Software Sector ETF
IGV
|
+$348M |
| 4 |
Thermo Fisher Scientific
TMO
|
+$292M |
| 5 |
Snowflake
SNOW
|
+$258M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 16.18% |
| 2 | Financials | 15.54% |
| 3 | Industrials | 10.5% |
| 4 | Healthcare | 9.8% |
| 5 | Consumer Discretionary | 8.1% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
2301
Atea Pharmaceuticals
AVIR
$436M
| $1.37M | ﹤0.01% |
471,293
+104,681
| +29% | +$357K |
|
2302
First Community Bankshares
FCBC
$933M
| $1.37M | ﹤0.01% |
+39,241
| New | +$1.48M |
|
2303
First Internet Bancorp
INBK
$249M
| $1.37M | ﹤0.01% |
60,882
+21,587
| +55% | +$532K |
|
2304
Columbus McKinnon
CMCO
$513M
| $1.36M | ﹤0.01% |
+95,094
| New | +$1.43M |
|
2305
PUT
Valero Energy
VLO
$98B
| $1.36M | ﹤0.01% |
+8,000
| New | +$1.19M |
|
2306
American Battery Technology Co
ABAT
$353M
| $1.36M | ﹤0.01% |
280,234
+135,224
| +93% | +$353K |
|
2307
Quanterix
QTRX
$132M
| $1.36M | ﹤0.01% |
250,074
+7,385
| +3% | +$39.3K |
|
|
VTYX
2308
DELISTED
Ventyx Biosciences
VTYX
| $1.36M | ﹤0.01% |
+436,082
| New | +$1.16M |
|
2309
ALPS O'Shares U.S. Quality Dividend ETF
OUSA
$760M
| $1.35M | ﹤0.01% |
23,900
+5,000
| +26% | +$276K |
|
|
HNGE
2310
Hinge Health
HNGE
$7.25B
| $1.35M | ﹤0.01% |
27,513
+16,048
| +140% | +$839K |
|
|
SERV
2311
Serve Robotics
SERV
$423M
| $1.35M | ﹤0.01% |
115,990
-89,216
| -43% | -$978K |
|
2312
Global X Adaptive US Factor ETF
AUSF
$919M
| $1.35M | ﹤0.01% |
+29,000
| New | +$1.32M |
|
2313
Sabre
SABR
$912M
| $1.35M | ﹤0.01% |
735,692
-1,865,292
| -72% | -$4.4M |
|
2314
Academy Sports + Outdoors
ASO
$2.7B
| $1.35M | ﹤0.01% |
26,895
-367
| -1% | -$18.7K |
|
2315
Limbach Holdings
LMB
$500M
| $1.34M | ﹤0.01% |
13,816
+52
| +0.4% | +$6.26K |
|
2316
Privia Health
PRVA
$2.71B
| $1.34M | ﹤0.01% |
53,848
-139,080
| -72% | -$2.99M |
|
2317
Spire Global
SPIR
$558M
| $1.34M | ﹤0.01% |
121,963
+98,440
| +418% | +$1.02M |
|
2318
Amylyx Pharmaceuticals
AMLX
$4.17B
| $1.34M | ﹤0.01% |
98,416
-460,430
| -82% | -$4.33M |
|
2319
Milestone Pharmaceuticals
MIST
$144M
| $1.33M | ﹤0.01% |
+666,551
| New | +$1.17M |
|
2320
Orange County Bancorp
OBT
$507M
| $1.33M | ﹤0.01% |
52,862
+19,995
| +61% | +$522K |
|
2321
Navigator Holdings
NVGS
$1.36B
| $1.33M | ﹤0.01% |
85,817
+27,916
| +48% | +$446K |
|
2322
PUT
Nike
NKE
$58.6B
| $1.32M | ﹤0.01% |
+19,000
| New | +$1.42M |
|
|
PLGO
2323
Pelagos Insurance Capital
PLGO
$2.07B
| $1.32M | ﹤0.01% |
72,974
-50,154
| -41% | -$837K |
|
2324
AST SpaceMobile
ASTS
$18.6B
| $1.32M | ﹤0.01% |
26,948
-344,717
| -93% | -$16.6M |
|
2325
Farmers National Banc Corp
FMNB
$925M
| $1.32M | ﹤0.01% |
91,681
+12,926
| +16% | +$185K |
|
Similar funds
John Overdeck's Q3 2025 Portfolio in Review
As of Q3 2025, John Overdeck held 4,027 positions worth $67.2B, up 19% from $56.5B the previous quarter. Its ten largest holdings account for 6.2% of the portfolio.
John Overdeck deployed $4.46B of net new capital in Q3 2025, opening 877 new positions and adding to 1,461 existing holdings. Its largest new stake was Berkshire Hathaway Class B: 379,096 shares worth $191M.
By sector, the portfolio is most concentrated in Technology at 16% of assets, down from 17% a quarter earlier, followed by Financials and Industrials.
On the sell side, the largest reduction was Invesco QQQ Trust, an estimated $381M trimmed.
- John Overdeck's largest Q3 2025 buy was Berkshire Hathaway Class B: 379,096 shares worth $191M.
- John Overdeck added most to State Street Financial Select Sector SPDR ETF in Q3 2025, an estimated $474M increase.
- John Overdeck's biggest Q3 2025 reduction was Invesco QQQ Trust, cutting an estimated $381M.
- John Overdeck fully exited NextEra Energy, Inc. 6.926% Corporate Units in Q3 2025, selling an estimated $115M.
- John Overdeck's ten largest holdings make up 6.2% of its $67.2B portfolio in Q3 2025.
- John Overdeck opened 877 new positions and closed 399 in Q3 2025.
- John Overdeck's portfolio value rose 19% quarter-over-quarter to $67.2B.
Based on Two Sigma Investments's 13F filing for Q3 2025, filed 14 Nov 2025.