John Overdeck Two Sigma Investments
John Overdeck is a co-founder of Two Sigma Investments, one of the world’s leading quantitative and technology-driven investment firms. Two Sigma applies data science, machine learning, and large-scale computing to markets across asset classes. Overdeck’s firm is a central reference point in discussions of modern systematic investing.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street Financial Select Sector SPDR ETF
XLF
|
+$474M |
| 2 |
State Street Consumer Staples Select Sector SPDR ETF
XLP
|
+$357M |
| 3 |
Accenture
ACN
|
+$246M |
| 4 |
Advanced Micro Devices
AMD
|
+$235M |
| 5 |
State Street SPDR Dow Jones Industrial Average ETF Trust
DIA
|
+$231M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Invesco QQQ Trust
QQQ
|
+$381M |
| 2 |
State Street Technology Select Sector SPDR ETF
XLK
|
+$375M |
| 3 |
iShares Expanded Tech-Software Sector ETF
IGV
|
+$348M |
| 4 |
Thermo Fisher Scientific
TMO
|
+$292M |
| 5 |
Snowflake
SNOW
|
+$258M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 16.18% |
| 2 | Financials | 15.54% |
| 3 | Industrials | 10.5% |
| 4 | Healthcare | 9.8% |
| 5 | Consumer Discretionary | 8.1% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
2226
CALL
Walmart Inc
WMT
$839B
| $1.55M | ﹤0.01% |
+15,000
| New | +$1.49M |
|
2227
Primis Financial Corp
FRST
$398M
| $1.54M | ﹤0.01% |
146,429
+47,679
| +48% | +$532K |
|
2228
State Street SPDR EURO STOXX 50 ETF
FEZ
$4.55B
| $1.53M | ﹤0.01% |
+24,700
| New | +$1.48M |
|
|
TEM
2229
PUT
Tempus AI
TEM
$12.4B
| $1.53M | ﹤0.01% |
+19,000
| New | +$1.33M |
|
2230
Hamilton Lane
HLNE
$4.63B
| $1.53M | ﹤0.01% |
11,376
+6,300
| +124% | +$950K |
|
2231
Ambarella
AMBA
$3.1B
| $1.53M | ﹤0.01% |
18,568
-12,188
| -40% | -$885K |
|
2232
James River Group Holdings
JRVR
$191M
| $1.53M | ﹤0.01% |
275,753
+63,914
| +30% | +$359K |
|
|
SKYT
2233
DELISTED
SkyWater Technology
SKYT
| $1.53M | ﹤0.01% |
81,853
+64,946
| +384% | +$751K |
|
|
BRY
2234
DELISTED
Berry Corp
BRY
| $1.53M | ﹤0.01% |
403,963
-54,160
| -12% | -$176K |
|
2235
PUT
Eli Lilly
LLY
$1.1T
| $1.53M | ﹤0.01% |
+2,000
| New | +$1.49M |
|
2236
PUT
McDonald's
MCD
$190B
| $1.52M | ﹤0.01% |
+5,000
| New | +$1.52M |
|
2237
Douglas Elliman
DOUG
$177M
| $1.52M | ﹤0.01% |
530,779
+144,227
| +37% | +$378K |
|
2238
NovoCure
NVCR
$2.05B
| $1.52M | ﹤0.01% |
117,367
-77,969
| -40% | -$1.04M |
|
2239
Healthcare Services Group
HCSG
$1.57B
| $1.52M | ﹤0.01% |
90,080
-25,623
| -22% | -$381K |
|
2240
iShares 20+ Year Treasury Bond ETF
TLT
$47.1B
| $1.51M | ﹤0.01% |
16,847
-1,096,975
| -98% | -$95.9M |
|
|
BCAX
2241
Bicara Therapeutics
BCAX
$1.63B
| $1.5M | ﹤0.01% |
95,238
-39,219
| -29% | -$439K |
|
2242
Fidelity US Multifactor ETF
FLRG
$298M
| $1.5M | ﹤0.01% |
39,000
-4,400
| -10% | -$163K |
|
2243
WaFd
WAFD
$2.68B
| $1.5M | ﹤0.01% |
49,497
+8,354
| +20% | +$256K |
|
2244
Corvus Pharmaceuticals
CRVS
$1.22B
| $1.5M | ﹤0.01% |
203,360
-20,553
| -9% | -$105K |
|
2245
iShares Silver Trust
SLV
$33.5B
| $1.5M | ﹤0.01% |
35,336
+17,920
| +103% | +$644K |
|
2246
BlackRock Resources & Commodities Strategy Trust
BCX
$1.01B
| $1.5M | ﹤0.01% |
147,166
| – | – |
|
2247
CorMedix
CRMD
$667M
| $1.5M | ﹤0.01% |
128,555
-188,408
| -59% | -$2.28M |
|
2248
Revvity
RVTY
$13.9B
| $1.49M | ﹤0.01% |
17,051
+14,448
| +555% | +$1.31M |
|
2249
PTC Therapeutics
PTCT
$6.13B
| $1.49M | ﹤0.01% |
24,341
-26,510
| -52% | -$1.38M |
|
2250
Regenxbio
RGNX
$588M
| $1.49M | ﹤0.01% |
154,286
-53,665
| -26% | -$475K |
|
Similar funds
John Overdeck's Q3 2025 Portfolio in Review
As of Q3 2025, John Overdeck held 4,027 positions worth $67.2B, up 19% from $56.5B the previous quarter. Its ten largest holdings account for 6.2% of the portfolio.
John Overdeck deployed $4.46B of net new capital in Q3 2025, opening 877 new positions and adding to 1,461 existing holdings. Its largest new stake was Berkshire Hathaway Class B: 379,096 shares worth $191M.
By sector, the portfolio is most concentrated in Technology at 16% of assets, down from 17% a quarter earlier, followed by Financials and Industrials.
On the sell side, the largest reduction was Invesco QQQ Trust, an estimated $381M trimmed.
- John Overdeck's largest Q3 2025 buy was Berkshire Hathaway Class B: 379,096 shares worth $191M.
- John Overdeck added most to State Street Financial Select Sector SPDR ETF in Q3 2025, an estimated $474M increase.
- John Overdeck's biggest Q3 2025 reduction was Invesco QQQ Trust, cutting an estimated $381M.
- John Overdeck fully exited NextEra Energy, Inc. 6.926% Corporate Units in Q3 2025, selling an estimated $115M.
- John Overdeck's ten largest holdings make up 6.2% of its $67.2B portfolio in Q3 2025.
- John Overdeck opened 877 new positions and closed 399 in Q3 2025.
- John Overdeck's portfolio value rose 19% quarter-over-quarter to $67.2B.
Based on Two Sigma Investments's 13F filing for Q3 2025, filed 14 Nov 2025.