John Overdeck Two Sigma Investments
John Overdeck is a co-founder of Two Sigma Investments, one of the world’s leading quantitative and technology-driven investment firms. Two Sigma applies data science, machine learning, and large-scale computing to markets across asset classes. Overdeck’s firm is a central reference point in discussions of modern systematic investing.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street Financial Select Sector SPDR ETF
XLF
|
+$474M |
| 2 |
State Street Consumer Staples Select Sector SPDR ETF
XLP
|
+$357M |
| 3 |
Accenture
ACN
|
+$246M |
| 4 |
Advanced Micro Devices
AMD
|
+$235M |
| 5 |
State Street SPDR Dow Jones Industrial Average ETF Trust
DIA
|
+$231M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Invesco QQQ Trust
QQQ
|
+$381M |
| 2 |
State Street Technology Select Sector SPDR ETF
XLK
|
+$375M |
| 3 |
iShares Expanded Tech-Software Sector ETF
IGV
|
+$348M |
| 4 |
Thermo Fisher Scientific
TMO
|
+$292M |
| 5 |
Snowflake
SNOW
|
+$258M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 16.18% |
| 2 | Financials | 15.54% |
| 3 | Industrials | 10.5% |
| 4 | Healthcare | 9.8% |
| 5 | Consumer Discretionary | 8.1% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
1226
Avista
AVA
$3.18B
| $6.19M | 0.01% |
163,791
-90,864
| -36% | -$3.38M |
|
1227
First Financial Bankshares
FFIN
$4.87B
| $6.19M | 0.01% |
184,035
+58,321
| +46% | +$2.1M |
|
1228
Aptus Collared Investment Opportunity ETF
ACIO
$2.4B
| $6.19M | 0.01% |
142,500
+109,500
| +332% | +$4.63M |
|
1229
Powell Industries
POWL
$6.89B
| $6.19M | 0.01% |
60,900
-53,538
| -47% | -$4.54M |
|
1230
Qorvo
QRVO
$8.41B
| $6.17M | 0.01% |
67,717
-57
| -0.1% | -$5.08K |
|
|
CMPS
1231
Compass Pathways
CMPS
$1.97B
| $6.16M | 0.01% |
1,075,277
+960,685
| +838% | +$4.32M |
|
1232
LendingTree
TREE
$435M
| $6.15M | 0.01% |
+95,052
| New | +$5.48M |
|
1233
Invesco
IVZ
$14.3B
| $6.13M | 0.01% |
267,127
+150,489
| +129% | +$3.12M |
|
1234
iShares Morningstar Growth ETF
ILCG
$3.15B
| $6.12M | 0.01% |
58,700
-30,900
| -34% | -$3.1M |
|
1235
Runway Growth Finance
RWAY
$275M
| $6.12M | 0.01% |
602,410
+40,354
| +7% | +$433K |
|
1236
Hovnanian Enterprises
HOV
$739M
| $6.11M | 0.01% |
47,574
+15,041
| +46% | +$2.01M |
|
|
FFIC
1237
DELISTED
Flushing Financial
FFIC
| $6.1M | 0.01% |
441,975
+51,996
| +13% | +$677K |
|
1238
Linde
LIN
$226B
| $6.09M | 0.01% |
12,828
-91,043
| -88% | -$43.1M |
|
1239
Novavax
NVAX
$1.46B
| $6.09M | 0.01% |
702,000
+162,754
| +30% | +$1.27M |
|
1240
Safety Insurance
SAFT
$1.52B
| $6.08M | 0.01% |
86,026
+68,399
| +388% | +$4.97M |
|
1241
Criteo S.A.
CRTO
$837M
| $6.06M | 0.01% |
268,143
+110,574
| +70% | +$2.59M |
|
1242
Gossamer Bio
GOSS
$85.5M
| $6.02M | 0.01% |
2,287,251
+542,124
| +31% | +$1.19M |
|
1243
Pacira BioSciences
PCRX
$991M
| $6M | 0.01% |
232,994
+126,152
| +118% | +$3.1M |
|
|
VTLE
1244
DELISTED
Vital Energy
VTLE
| $5.99M | 0.01% |
354,765
+35,270
| +11% | +$596K |
|
1245
SouthState Bank Corp
SSB
$10.4B
| $5.98M | 0.01% |
60,477
-36,413
| -38% | -$3.58M |
|
1246
Vistra
VST
$45.5B
| $5.98M | 0.01% |
30,512
-4,200
| -12% | -$832K |
|
1247
Boeing
BA
$166B
| $5.96M | 0.01% |
27,600
-85,740
| -76% | -$19.3M |
|
1248
RxSight
RXST
$260M
| $5.96M | 0.01% |
662,417
+221,961
| +50% | +$1.95M |
|
1249
Iovance Biotherapeutics
IOVA
$3.65B
| $5.95M | 0.01% |
2,740,854
-1,892,597
| -41% | -$4.47M |
|
|
ESPR
1250
DELISTED
Esperion Therapeutics
ESPR
| $5.93M | 0.01% |
2,238,618
+410,624
| +22% | +$794K |
|
Similar funds
John Overdeck's Q3 2025 Portfolio in Review
As of Q3 2025, John Overdeck held 4,027 positions worth $67.2B, up 19% from $56.5B the previous quarter. Its ten largest holdings account for 6.2% of the portfolio.
John Overdeck deployed $4.46B of net new capital in Q3 2025, opening 877 new positions and adding to 1,461 existing holdings. Its largest new stake was Berkshire Hathaway Class B: 379,096 shares worth $191M.
By sector, the portfolio is most concentrated in Technology at 16% of assets, down from 17% a quarter earlier, followed by Financials and Industrials.
On the sell side, the largest reduction was Invesco QQQ Trust, an estimated $381M trimmed.
- John Overdeck's largest Q3 2025 buy was Berkshire Hathaway Class B: 379,096 shares worth $191M.
- John Overdeck added most to State Street Financial Select Sector SPDR ETF in Q3 2025, an estimated $474M increase.
- John Overdeck's biggest Q3 2025 reduction was Invesco QQQ Trust, cutting an estimated $381M.
- John Overdeck fully exited NextEra Energy, Inc. 6.926% Corporate Units in Q3 2025, selling an estimated $115M.
- John Overdeck's ten largest holdings make up 6.2% of its $67.2B portfolio in Q3 2025.
- John Overdeck opened 877 new positions and closed 399 in Q3 2025.
- John Overdeck's portfolio value rose 19% quarter-over-quarter to $67.2B.
Based on Two Sigma Investments's 13F filing for Q3 2025, filed 14 Nov 2025.