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JO

John Overdeck Two Sigma Investments

AUM $138B
1-Year Est. Return 41.87%
 

John Overdeck is a co-founder of Two Sigma Investments, one of the world’s leading quantitative and technology-driven investment firms. Two Sigma applies data science, machine learning, and large-scale computing to markets across asset classes. Overdeck’s firm is a central reference point in discussions of modern systematic investing.

This Fund
S&P 500
This Quarter Est. Return
+3.47%
1 Year Est. Return
+41.87%
3 Year Est. Return
+122.61%
5 Year Est. Return
+129.48%
10 Year Est. Return
+649.67%
AUM
$70.9B
AUM Growth
+$3.72B
Cap. Flow
+$541M
Cap. Flow %
0.76%
Top 10 Hldgs %
4.9%
Holding
4,545
New
899
Increased
1,598
Reduced
1,287
Closed
504

Sector Composition

Rank Sector Weight
1 Technology 15.53%
2 Financials 13%
3 Industrials 11.22%
4 Healthcare 10.29%
5 Consumer Discretionary 9.16%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
MEGL icon
3901
Magic Empire Global Ltd
MEGL
$5.92M
$20.9K ﹤0.01%
+17,771
New +$24.2K
CASI
3902
DELISTED
CASI Pharmaceuticals
CASI
$20.2K ﹤0.01%
23,787
-9,480
-28% -$12.3K
CURX
3903
Curanex Pharmaceuticals
CURX
$7.39M
$20.2K ﹤0.01%
+3,055
New +$33.6K
IBO
3904
Impact BioMedical
IBO
$51.8M
$20.1K ﹤0.01%
39,827
+8,327
+26% +$4.41K
AMBR
3905
Amber International Holding Ltd
AMBR
$92M
$19.9K ﹤0.01%
11,502
-1,111
-9% -$2.19K
MYPS icon
3906
PLAYSTUDIOS Inc
MYPS
$63.3M
$19K ﹤0.01%
29,101
-123,965
-81% -$96.5K
MDCX
3907
Medicus Pharma
MDCX
$17.2M
$18.8K ﹤0.01%
+12,319
New +$26.4K
BIOX icon
3908
Bioceres Crop Solutions
BIOX
$28.1M
$18.6K ﹤0.01%
+14,182
New +$22.7K
APM
3909
DELISTED
Aptorum Group
APM
$18.5K ﹤0.01%
+17,411
New +$25.6K
PWCM
3910
PowerCompute Inc
PWCM
$1.26M
$17.9K ﹤0.01%
1,612
-1,887
-54% -$45.1K
WSTNR
3911
Westin Acquisition Corp Right
WSTNR
$16.3K ﹤0.01%
+90,625
New +$16.3K
NAMM
3912
Namib Minerals
NAMM
$84.3M
$16.2K ﹤0.01%
+16,051
New +$29.6K
BBLG
3913
Bone Biologics
BBLG
$1.73M
$16.1K ﹤0.01%
+11,083
New +$22.1K
EDUC icon
3914
Educational Development Corp
EDUC
$11.7M
$15.9K ﹤0.01%
+12,052
New +$16.5K
JOB icon
3915
GEE Group
JOB
$27M
$15.7K ﹤0.01%
80,700
-39,826
-33% -$7.74K
PHIO icon
3916
Phio Pharmaceuticals
PHIO
$13.7M
$15.2K ﹤0.01%
+14,494
New +$23.2K
FEMY icon
3917
Femasys
FEMY
$24.8M
$15.1K ﹤0.01%
+1,307
New +$19.8K
KALA icon
3918
KALA BIO
KALA
$15.9M
$15K ﹤0.01%
+538
New +$24.1K
TRIB
3919
Trinity Biotech
TRIB
$8.62M
$14.8K ﹤0.01%
622
-178
-22% -$5.25K
CNEY icon
3920
CN Energy Group
CNEY
$5.73M
$14.6K ﹤0.01%
+23,833
New +$35.5K
BCDA icon
3921
BioCardia
BCDA
$15.3M
$14K ﹤0.01%
+11,229
New +$15.3K
ATOS icon
3922
Atossa Therapeutics
ATOS
$25.3M
$13.8K ﹤0.01%
+1,563
New +$19.8K
HKPD
3923
Cellyan Biotechnology
HKPD
$19.8M
$13.8K ﹤0.01%
+16,751
New +$18K
HUDI icon
3924
Huadi International Group
HUDI
$14.2M
$13.7K ﹤0.01%
+12,205
New +$15.8K
UAVS icon
3925
AgEagle Aerial Systems
UAVS
$63.5M
$13.3K ﹤0.01%
16,400
-4,489
-21% -$6.99K

Similar funds

John Overdeck's Q4 2025 Portfolio in Review

As of Q4 2025, John Overdeck held 4,545 positions worth $70.9B, up 5.5% from $67.2B the previous quarter. Its ten largest holdings account for 4.9% of the portfolio.

John Overdeck's Q4 2025 filing shows 899 new, 1,598 increased, 1,287 reduced and 504 closed positions. Its largest new stake was Vanguard Real Estate ETF: 3,573,400 shares worth $316M. The largest sale was State Street Financial Select Sector SPDR ETF, an estimated $547M.

By sector, the portfolio is most concentrated in Technology at 16% of assets, down from 16% a quarter earlier, followed by Financials and Industrials.

  • John Overdeck's largest Q4 2025 buy was Vanguard Real Estate ETF: 3,573,400 shares worth $316M.
  • John Overdeck added most to State Street Technology Select Sector SPDR ETF in Q4 2025, an estimated $395M increase.
  • John Overdeck's biggest Q4 2025 reduction was State Street Financial Select Sector SPDR ETF, cutting an estimated $547M.
  • John Overdeck fully exited State Street SPDR Dow Jones Industrial Average ETF Trust in Q4 2025, selling an estimated $240M.
  • John Overdeck's ten largest holdings make up 4.9% of its $70.9B portfolio in Q4 2025.
  • John Overdeck opened 899 new positions and closed 504 in Q4 2025.
  • John Overdeck's portfolio value rose 5.5% quarter-over-quarter to $70.9B.

Based on Two Sigma Investments's 13F filing for Q4 2025, filed 17 Feb 2026.