John Overdeck Two Sigma Investments
John Overdeck is a co-founder of Two Sigma Investments, one of the world’s leading quantitative and technology-driven investment firms. Two Sigma applies data science, machine learning, and large-scale computing to markets across asset classes. Overdeck’s firm is a central reference point in discussions of modern systematic investing.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street Financial Select Sector SPDR ETF
XLF
|
+$474M |
| 2 |
State Street Consumer Staples Select Sector SPDR ETF
XLP
|
+$357M |
| 3 |
Accenture
ACN
|
+$246M |
| 4 |
Advanced Micro Devices
AMD
|
+$235M |
| 5 |
State Street SPDR Dow Jones Industrial Average ETF Trust
DIA
|
+$231M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Invesco QQQ Trust
QQQ
|
+$381M |
| 2 |
State Street Technology Select Sector SPDR ETF
XLK
|
+$375M |
| 3 |
iShares Expanded Tech-Software Sector ETF
IGV
|
+$348M |
| 4 |
Thermo Fisher Scientific
TMO
|
+$292M |
| 5 |
Snowflake
SNOW
|
+$258M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 16.18% |
| 2 | Financials | 15.54% |
| 3 | Industrials | 10.5% |
| 4 | Healthcare | 9.8% |
| 5 | Consumer Discretionary | 8.1% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
3501
BioAtla
BCAB
$5.91M
| $28K | ﹤0.01% |
814
-838
| -51% | -$19.3K |
|
3502
Citius Pharmaceuticals
CTXR
$16M
| $27K | ﹤0.01% |
21,803
+8,929
| +69% | +$12.4K |
|
3503
NN Inc
NNBR
$306M
| $26.8K | ﹤0.01% |
+13,020
| New | +$29.2K |
|
3504
Strive Inc
ASST
$1.71B
| $26.8K | ﹤0.01% |
+535
| New | +$50.9K |
|
3505
NeuroSense Therapeutics
NRSN
$14.2M
| $26.4K | ﹤0.01% |
+21,086
| New | +$30.9K |
|
3506
Pasithea Therapeutics
KTTA
$18M
| $26.2K | ﹤0.01% |
+35,760
| New | +$26.1K |
|
3507
Theriva Biologics
TOVX
$11.1M
| $25.1K | ﹤0.01% |
+61,837
| New | +$26.8K |
|
|
TRIB
3508
Trinity Biotech
TRIB
$8.13M
| $24.9K | ﹤0.01% |
800
+298
| +59% | +$9.39K |
|
3509
GEE Group
JOB
$28.6M
| $24.9K | ﹤0.01% |
120,526
-3,427
| -3% | -$696 |
|
3510
Quince Therapeutics
QNCX
$33.1M
| $24.6K | ﹤0.01% |
75
-12
| -14% | -$4K |
|
3511
Battalion Oil
BATL
$75.6M
| $24.4K | ﹤0.01% |
+20,196
| New | +$24.7K |
|
|
ORGN
3512
DELISTED
Origin Materials
ORGN
| $24K | ﹤0.01% |
+1,542
| New | +$28.6K |
|
3513
Beneficient
BENF
$33.2M
| $22.6K | ﹤0.01% |
+2,971
| New | +$8.69K |
|
3514
Senti Biosciences Holdings
SNTI
$10.5M
| $22.5K | ﹤0.01% |
+15,968
| New | +$26.7K |
|
|
STAI
3515
DELISTED
ScanTech AI Systems
STAI
| $22.4K | ﹤0.01% |
2,703
-666
| -20% | -$7.28K |
|
|
IOTR
3516
iOThree Ltd
IOTR
$12.3M
| $22K | ﹤0.01% |
5,774
+1,988
| +53% | +$8.53K |
|
|
FFAI
3517
Faraday Future Intelligent Electric
FFAI
$11.9M
| $22K | ﹤0.01% |
113
-756
| -87% | -$239K |
|
|
ALLR
3518
Allarity Therapeutics
ALLR
$22M
| $22K | ﹤0.01% |
+13,910
| New | +$17.5K |
|
|
GORV
3519
DELISTED
Lazydays
GORV
| $21.8K | ﹤0.01% |
+10,470
| New | +$46.6K |
|
|
IBO
3520
Impact BioMedical
IBO
$50.2M
| $20.9K | ﹤0.01% |
31,500
+8,800
| +39% | +$5.55K |
|
|
RPTX
3521
DELISTED
Repare Therapeutics
RPTX
| $19.3K | ﹤0.01% |
10,967
-21,288
| -66% | -$34.1K |
|
|
AIFA
3522
All In FutureTech Alliance Inc
AIFA
$19.8M
| $19.1K | ﹤0.01% |
+3,463
| New | +$29.3K |
|
3523
Kaltura
KLTR
$249M
| $18.1K | ﹤0.01% |
12,583
-56,520
| -82% | -$95.3K |
|
|
GRML
3524
Greenland Mines Ltd
GRML
$28.6M
| $17.7K | ﹤0.01% |
+731
| New | +$31.7K |
|
3525
iPower
IPW
$544K
| $17.1K | ﹤0.01% |
15
+8
| +114% | +$10.2K |
|
Similar funds
John Overdeck's Q3 2025 Portfolio in Review
As of Q3 2025, John Overdeck held 4,027 positions worth $67.2B, up 19% from $56.5B the previous quarter. Its ten largest holdings account for 6.2% of the portfolio.
John Overdeck deployed $4.46B of net new capital in Q3 2025, opening 877 new positions and adding to 1,461 existing holdings. Its largest new stake was Berkshire Hathaway Class B: 379,096 shares worth $191M.
By sector, the portfolio is most concentrated in Technology at 16% of assets, down from 17% a quarter earlier, followed by Financials and Industrials.
On the sell side, the largest reduction was Invesco QQQ Trust, an estimated $381M trimmed.
- John Overdeck's largest Q3 2025 buy was Berkshire Hathaway Class B: 379,096 shares worth $191M.
- John Overdeck added most to State Street Financial Select Sector SPDR ETF in Q3 2025, an estimated $474M increase.
- John Overdeck's biggest Q3 2025 reduction was Invesco QQQ Trust, cutting an estimated $381M.
- John Overdeck fully exited NextEra Energy, Inc. 6.926% Corporate Units in Q3 2025, selling an estimated $115M.
- John Overdeck's ten largest holdings make up 6.2% of its $67.2B portfolio in Q3 2025.
- John Overdeck opened 877 new positions and closed 399 in Q3 2025.
- John Overdeck's portfolio value rose 19% quarter-over-quarter to $67.2B.
Based on Two Sigma Investments's 13F filing for Q3 2025, filed 14 Nov 2025.