John Overdeck Two Sigma Investments
John Overdeck is a co-founder of Two Sigma Investments, one of the world’s leading quantitative and technology-driven investment firms. Two Sigma applies data science, machine learning, and large-scale computing to markets across asset classes. Overdeck’s firm is a central reference point in discussions of modern systematic investing.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street Financial Select Sector SPDR ETF
XLF
|
+$474M |
| 2 |
State Street Consumer Staples Select Sector SPDR ETF
XLP
|
+$357M |
| 3 |
Accenture
ACN
|
+$246M |
| 4 |
Advanced Micro Devices
AMD
|
+$235M |
| 5 |
State Street SPDR Dow Jones Industrial Average ETF Trust
DIA
|
+$231M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Invesco QQQ Trust
QQQ
|
+$381M |
| 2 |
State Street Technology Select Sector SPDR ETF
XLK
|
+$375M |
| 3 |
iShares Expanded Tech-Software Sector ETF
IGV
|
+$348M |
| 4 |
Thermo Fisher Scientific
TMO
|
+$292M |
| 5 |
Snowflake
SNOW
|
+$258M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 16.18% |
| 2 | Financials | 15.54% |
| 3 | Industrials | 10.5% |
| 4 | Healthcare | 9.8% |
| 5 | Consumer Discretionary | 8.1% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
3326
Energy Fuels
UUUU
$3.72B
| $170K | ﹤0.01% |
+11,100
| New | +$118K |
|
3327
MIND Technology
MIND
$39M
| $170K | ﹤0.01% |
21,058
-6,985
| -25% | -$62.8K |
|
|
RWT
3328
Redwood Trust
RWT
$598M
| $170K | ﹤0.01% |
29,340
-90,593
| -76% | -$542K |
|
3329
RF Industries
RFIL
$116M
| $169K | ﹤0.01% |
+20,558
| New | +$153K |
|
|
OSTX
3330
OS Therapies Inc
OSTX
$71.5M
| $169K | ﹤0.01% |
+86,247
| New | +$171K |
|
|
GGZ
3331
Gabelli Global Small and Mid-Cap Value Trust
GGZ
$126M
| $168K | ﹤0.01% |
11,601
-4,521
| -28% | -$63.2K |
|
|
DBVT
3332
DBV Technologies
DBVT
$889M
| $167K | ﹤0.01% |
+16,682
| New | +$162K |
|
3333
Children's Place
PLCE
$58M
| $166K | ﹤0.01% |
+26,733
| New | +$145K |
|
3334
Hamilton Beach Brands
HBB
$450M
| $164K | ﹤0.01% |
+11,437
| New | +$179K |
|
3335
Odyssey Marine Exploration
OMEX
$52.8M
| $164K | ﹤0.01% |
84,029
+47,145
| +128% | +$76K |
|
|
SLI
3336
Standard Lithium
SLI
$600M
| $160K | ﹤0.01% |
+47,594
| New | +$133K |
|
|
BZAI
3337
Blaize Holdings
BZAI
$65.2M
| $159K | ﹤0.01% |
+46,074
| New | +$164K |
|
3338
Hour Loop
HOUR
$63.4M
| $159K | ﹤0.01% |
+54,226
| New | +$116K |
|
|
SLAI
3339
DELISTED
SOLAI Ltd ADS
SLAI
| $156K | ﹤0.01% |
+8,272
| New | +$173K |
|
3340
Enel Chile
ENIC
$6.27B
| $153K | ﹤0.01% |
39,225
| – | – |
|
|
ATYR
3341
aTyr Pharma
ATYR
$52M
| $152K | ﹤0.01% |
211,000
+179,672
| +574% | +$814K |
|
3342
Richtech Robotics
RR
$362M
| $152K | ﹤0.01% |
35,473
+4,429
| +14% | +$11.6K |
|
|
TRUE
3343
DELISTED
TrueCar
TRUE
| $151K | ﹤0.01% |
+81,994
| New | +$165K |
|
3344
Virgin Galactic
SPCE
$455M
| $150K | ﹤0.01% |
38,971
-181,544
| -82% | -$608K |
|
|
ACOG
3345
Alpha Cognition
ACOG
$212M
| $148K | ﹤0.01% |
+22,728
| New | +$207K |
|
3346
PLAYSTUDIOS Inc
MYPS
$60.3M
| $147K | ﹤0.01% |
153,066
-3,318
| -2% | -$3.57K |
|
3347
Senseonics Holdings Inc
SENS
$496M
| $146K | ﹤0.01% |
16,732
-75,363
| -82% | -$728K |
|
3348
UNIFI
UFI
$142M
| $144K | ﹤0.01% |
30,166
-10,487
| -26% | -$48.3K |
|
|
MTLS
3349
Materialise
MTLS
$387M
| $139K | ﹤0.01% |
24,994
-19,921
| -44% | -$107K |
|
3350
OraSure Technologies
OSUR
$263M
| $139K | ﹤0.01% |
43,300
-7,600
| -15% | -$23.9K |
|
Similar funds
John Overdeck's Q3 2025 Portfolio in Review
As of Q3 2025, John Overdeck held 4,027 positions worth $67.2B, up 19% from $56.5B the previous quarter. Its ten largest holdings account for 6.2% of the portfolio.
John Overdeck deployed $4.46B of net new capital in Q3 2025, opening 877 new positions and adding to 1,461 existing holdings. Its largest new stake was Berkshire Hathaway Class B: 379,096 shares worth $191M.
By sector, the portfolio is most concentrated in Technology at 16% of assets, down from 17% a quarter earlier, followed by Financials and Industrials.
On the sell side, the largest reduction was Invesco QQQ Trust, an estimated $381M trimmed.
- John Overdeck's largest Q3 2025 buy was Berkshire Hathaway Class B: 379,096 shares worth $191M.
- John Overdeck added most to State Street Financial Select Sector SPDR ETF in Q3 2025, an estimated $474M increase.
- John Overdeck's biggest Q3 2025 reduction was Invesco QQQ Trust, cutting an estimated $381M.
- John Overdeck fully exited NextEra Energy, Inc. 6.926% Corporate Units in Q3 2025, selling an estimated $115M.
- John Overdeck's ten largest holdings make up 6.2% of its $67.2B portfolio in Q3 2025.
- John Overdeck opened 877 new positions and closed 399 in Q3 2025.
- John Overdeck's portfolio value rose 19% quarter-over-quarter to $67.2B.
Based on Two Sigma Investments's 13F filing for Q3 2025, filed 14 Nov 2025.