John Overdeck Two Sigma Investments
John Overdeck is a co-founder of Two Sigma Investments, one of the world’s leading quantitative and technology-driven investment firms. Two Sigma applies data science, machine learning, and large-scale computing to markets across asset classes. Overdeck’s firm is a central reference point in discussions of modern systematic investing.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street Financial Select Sector SPDR ETF
XLF
|
+$474M |
| 2 |
State Street Consumer Staples Select Sector SPDR ETF
XLP
|
+$357M |
| 3 |
Accenture
ACN
|
+$246M |
| 4 |
Advanced Micro Devices
AMD
|
+$235M |
| 5 |
State Street SPDR Dow Jones Industrial Average ETF Trust
DIA
|
+$231M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Invesco QQQ Trust
QQQ
|
+$381M |
| 2 |
State Street Technology Select Sector SPDR ETF
XLK
|
+$375M |
| 3 |
iShares Expanded Tech-Software Sector ETF
IGV
|
+$348M |
| 4 |
Thermo Fisher Scientific
TMO
|
+$292M |
| 5 |
Snowflake
SNOW
|
+$258M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 16.18% |
| 2 | Financials | 15.54% |
| 3 | Industrials | 10.5% |
| 4 | Healthcare | 9.8% |
| 5 | Consumer Discretionary | 8.1% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
|
UHT
3026
Universal Health Realty Income Trust
UHT
$582M
| $389K | ﹤0.01% |
9,926
-37,181
| -79% | -$1.5M |
|
3027
Atlanticus Holdings
ATLC
$1.44B
| $388K | ﹤0.01% |
+6,626
| New | +$400K |
|
3028
Absci
ABSI
$1.52B
| $387K | ﹤0.01% |
127,155
-453,283
| -78% | -$1.25M |
|
|
HIT
3029
Health In Tech Inc
HIT
$63.6M
| $386K | ﹤0.01% |
+120,342
| New | +$288K |
|
|
JKS
3030
JinkoSolar
JKS
$846M
| $384K | ﹤0.01% |
+16,000
| New | +$377K |
|
3031
Toronto Dominion Bank
TD
$193B
| $384K | ﹤0.01% |
4,800
-79,210
| -94% | -$5.95M |
|
|
SFBS
3032
ServisFirst Bancshares
SFBS
$4.8B
| $383K | ﹤0.01% |
9,508
+2,578
| +37% | +$107K |
|
3033
Aligos Therapeutics
ALGS
$43.3M
| $382K | ﹤0.01% |
38,995
+26,922
| +223% | +$246K |
|
3034
W.W. Grainger
GWW
$62.3B
| $381K | ﹤0.01% |
400
| – | – |
|
3035
PUT
Medtronic
MDT
$119B
| $381K | ﹤0.01% |
+4,000
| New | +$368K |
|
|
CRESY
3036
Cresud
CRESY
$800M
| $381K | ﹤0.01% |
41,752
-8,883
| -18% | -$91.3K |
|
3037
Dycom Industries
DY
$11.4B
| $379K | ﹤0.01% |
1,300
-25,512
| -95% | -$6.69M |
|
3038
CALL
Warner Bros
WBD
$72B
| $379K | ﹤0.01% |
+19,400
| New | +$264K |
|
3039
Core Laboratories
CLB
$553M
| $378K | ﹤0.01% |
30,551
+5,160
| +20% | +$60.5K |
|
3040
PMV Pharmaceuticals
PMVP
$69.5M
| $377K | ﹤0.01% |
269,621
-21,834
| -7% | -$30.2K |
|
3041
PUT
Carvana
CVNA
$79.5B
| $377K | ﹤0.01% |
+5,000
| New | +$358K |
|
3042
Actinium Pharmaceuticals
ATNM
$32.9M
| $375K | ﹤0.01% |
234,293
+187,748
| +403% | +$306K |
|
3043
Essex Property Trust
ESS
$18.9B
| $375K | ﹤0.01% |
1,400
-800
| -36% | -$216K |
|
3044
EverCommerce
EVCM
$1.69B
| $371K | ﹤0.01% |
+33,359
| New | +$372K |
|
3045
Deluxe
DLX
$1.1B
| $371K | ﹤0.01% |
19,157
-8,449
| -31% | -$154K |
|
3046
Personalis
PSNL
$1.82B
| $370K | ﹤0.01% |
56,758
-135
| -0.2% | -$768 |
|
3047
PUT
Energy Fuels
UUUU
$3.72B
| $370K | ﹤0.01% |
+24,100
| New | +$256K |
|
3048
Invivyd
IVVD
$278M
| $369K | ﹤0.01% |
335,000
+96,308
| +40% | +$85.4K |
|
3049
Live Ventures
LIVE
$29M
| $368K | ﹤0.01% |
+20,025
| New | +$339K |
|
3050
Colterpoint Net Lease Real Estate ETF
NETL
$55.6M
| $367K | ﹤0.01% |
14,900
-700
| -4% | -$17.2K |
|
Similar funds
John Overdeck's Q3 2025 Portfolio in Review
As of Q3 2025, John Overdeck held 4,027 positions worth $67.2B, up 19% from $56.5B the previous quarter. Its ten largest holdings account for 6.2% of the portfolio.
John Overdeck deployed $4.46B of net new capital in Q3 2025, opening 877 new positions and adding to 1,461 existing holdings. Its largest new stake was Berkshire Hathaway Class B: 379,096 shares worth $191M.
By sector, the portfolio is most concentrated in Technology at 16% of assets, down from 17% a quarter earlier, followed by Financials and Industrials.
On the sell side, the largest reduction was Invesco QQQ Trust, an estimated $381M trimmed.
- John Overdeck's largest Q3 2025 buy was Berkshire Hathaway Class B: 379,096 shares worth $191M.
- John Overdeck added most to State Street Financial Select Sector SPDR ETF in Q3 2025, an estimated $474M increase.
- John Overdeck's biggest Q3 2025 reduction was Invesco QQQ Trust, cutting an estimated $381M.
- John Overdeck fully exited NextEra Energy, Inc. 6.926% Corporate Units in Q3 2025, selling an estimated $115M.
- John Overdeck's ten largest holdings make up 6.2% of its $67.2B portfolio in Q3 2025.
- John Overdeck opened 877 new positions and closed 399 in Q3 2025.
- John Overdeck's portfolio value rose 19% quarter-over-quarter to $67.2B.
Based on Two Sigma Investments's 13F filing for Q3 2025, filed 14 Nov 2025.