John Overdeck Two Sigma Investments
John Overdeck is a co-founder of Two Sigma Investments, one of the world’s leading quantitative and technology-driven investment firms. Two Sigma applies data science, machine learning, and large-scale computing to markets across asset classes. Overdeck’s firm is a central reference point in discussions of modern systematic investing.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
iShares Expanded Tech-Software Sector ETF
IGV
|
+$312M |
| 2 |
UnitedHealth
UNH
|
+$286M |
| 3 |
Duolingo
DUOL
|
+$247M |
| 4 |
Aon
AON
|
+$226M |
| 5 |
Chubb
CB
|
+$221M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Broadcom
AVGO
|
+$338M |
| 2 |
Marvell Technology
MRVL
|
+$241M |
| 3 |
Advanced Micro Devices
AMD
|
+$240M |
| 4 |
ServiceNow
NOW
|
+$203M |
| 5 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$193M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 16.79% |
| 2 | Financials | 14.46% |
| 3 | Healthcare | 12.9% |
| 4 | Consumer Discretionary | 8.97% |
| 5 | Industrials | 8.82% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
3026
Caesarstone
CSTE
$122M
| $26.2K | ﹤0.01% |
13,308
-4,409
| -25% | -$9.97K |
|
|
ITRM
3027
DELISTED
Iterum Therapeutics
ITRM
| $25.1K | ﹤0.01% |
25,245
| – | – |
|
3028
Cibus
CBUS
$130M
| $25.1K | ﹤0.01% |
18,163
+2,612
| +17% | +$5.32K |
|
|
RJET
3029
Republic Airways Holdings
RJET
$878M
| $24.9K | ﹤0.01% |
+1,783
| New | +$27.1K |
|
3030
GEE Group
JOB
$27M
| $24.4K | ﹤0.01% |
123,953
-111,132
| -47% | -$21.3K |
|
3031
MIRA Pharmaceuticals
MIRA
$32.1M
| $24.1K | ﹤0.01% |
19,887
-2,487
| -11% | -$2.87K |
|
3032
Traws Pharma
TRAW
$8.15M
| $23.8K | ﹤0.01% |
+16,063
| New | +$25.6K |
|
3033
Imunon
IMNN
$9.2M
| $23.7K | ﹤0.01% |
+2,268
| New | +$31K |
|
3034
Diana Shipping
DSX
$337M
| $23.2K | ﹤0.01% |
+15,900
| New | +$23.9K |
|
|
FLYE
3035
Fly-E Group
FLYE
$2.73M
| $23K | ﹤0.01% |
253
| – | – |
|
|
ABTC
3036
American Bitcoin Corp
ABTC
$577M
| $22.4K | ﹤0.01% |
+338
| New | +$17.5K |
|
3037
Gogoro
GGR
$45.6M
| $22.2K | ﹤0.01% |
3,896
-2,104
| -35% | -$11K |
|
3038
Rallybio
RLYB
$89.4M
| $21.6K | ﹤0.01% |
7,973
-366
| -4% | -$970 |
|
3039
Holley
HLLY
$375M
| $20.7K | ﹤0.01% |
+10,352
| New | +$22K |
|
3040
Metagenomi Therapeutics
MGX
$46.5M
| $20.6K | ﹤0.01% |
13,887
-44,461
| -76% | -$69.6K |
|
3041
Citius Pharmaceuticals
CTXR
$16.5M
| $20.5K | ﹤0.01% |
+12,874
| New | +$11.8K |
|
3042
Bridger Aerospace
BAER
$71.8M
| $19.9K | ﹤0.01% |
10,314
-27,278
| -73% | -$41.9K |
|
3043
Ostin Technology Group
OST
| $19.6K | ﹤0.01% |
+4,942
| New | +$499K |
|
3044
Energous
WATT
$69.8M
| $19.1K | ﹤0.01% |
+2,337
| New | +$19.4K |
|
3045
Passage Bio
PASG
$14.3M
| $18.9K | ﹤0.01% |
2,358
+10
| +0.4% | +$73 |
|
3046
Vince Holding Corp
VNCE
$80.3M
| $18.8K | ﹤0.01% |
13,062
-25,573
| -66% | -$41K |
|
3047
Cheche Group
CCG
$40.4M
| $18.5K | ﹤0.01% |
679
| – | – |
|
|
CAPS
3048
Capstone Holding Corp
CAPS
$3.89M
| $18.5K | ﹤0.01% |
+10,299
| New | +$20.3K |
|
3049
Usio Inc
USIO
$80.1M
| $17.9K | ﹤0.01% |
11,732
+1,697
| +17% | +$2.48K |
|
3050
DocGo
DCGO
$43M
| $17.8K | ﹤0.01% |
11,339
-76,765
| -87% | -$143K |
|
Similar funds
John Overdeck's Q2 2025 Portfolio in Review
As of Q2 2025, John Overdeck held 3,681 positions worth $56.5B, up 21% from $46.8B the previous quarter. Its ten largest holdings account for 7.7% of the portfolio.
John Overdeck deployed $2.96B of net new capital in Q2 2025, opening 509 new positions and adding to 1,200 existing holdings. Its largest new stake was iShares Expanded Tech-Software Sector ETF: 3,154,300 shares worth $345M.
By sector, the portfolio is most concentrated in Technology at 17% of assets, down from 18% a quarter earlier, followed by Financials and Healthcare.
On the sell side, the largest reduction was Broadcom, an estimated $338M trimmed.
- John Overdeck's largest Q2 2025 buy was iShares Expanded Tech-Software Sector ETF: 3,154,300 shares worth $345M.
- John Overdeck added most to UnitedHealth in Q2 2025, an estimated $286M increase.
- John Overdeck's biggest Q2 2025 reduction was Broadcom, cutting an estimated $338M.
- John Overdeck fully exited State Street Utilities Select Sector SPDR ETF in Q2 2025, selling an estimated $134M.
- John Overdeck's ten largest holdings make up 7.7% of its $56.5B portfolio in Q2 2025.
- John Overdeck opened 509 new positions and closed 531 in Q2 2025.
- John Overdeck's portfolio value rose 21% quarter-over-quarter to $56.5B.
Based on Two Sigma Investments's 13F filing for Q2 2025, filed 14 Aug 2025.