John Overdeck Two Sigma Investments
John Overdeck is a co-founder of Two Sigma Investments, one of the world’s leading quantitative and technology-driven investment firms. Two Sigma applies data science, machine learning, and large-scale computing to markets across asset classes. Overdeck’s firm is a central reference point in discussions of modern systematic investing.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$510M |
| 2 |
Broadcom
AVGO
|
+$318M |
| 3 |
Marvell Technology
MRVL
|
+$290M |
| 4 |
Salesforce
CRM
|
+$263M |
| 5 |
Advanced Micro Devices
AMD
|
+$250M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Eli Lilly
LLY
|
+$255M |
| 2 |
Progressive
PGR
|
+$244M |
| 3 |
Visa
V
|
+$238M |
| 4 |
Lam Research
LRCX
|
+$201M |
| 5 |
Elevance Health
ELV
|
+$190M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 17.88% |
| 2 | Healthcare | 13.28% |
| 3 | Financials | 10.32% |
| 4 | Industrials | 9.79% |
| 5 | Consumer Discretionary | 8.58% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
3026
Seres Therapeutics
MCRB
$47M
| $22.6K | ﹤0.01% |
1,616
+395
| +32% | +$6.18K |
|
3027
MIRA Pharmaceuticals
MIRA
$34M
| $21.9K | ﹤0.01% |
22,374
-1,943
| -8% | -$2.21K |
|
3028
SurgePays
SURG
$4.14M
| $21.6K | ﹤0.01% |
10,449
-1,400
| -12% | -$2.07K |
|
3029
Smith Micro Software
SMSI
$16.7M
| $21.2K | ﹤0.01% |
5,781
-561
| -9% | -$3.37K |
|
3030
BioVie
BIVI
$17.2M
| $21.2K | ﹤0.01% |
2,161
-710
| -25% | -$11.4K |
|
|
GLXG
3031
Galaxy Payroll Group
GLXG
$6.32M
| $21.1K | ﹤0.01% |
3,512
-949
| -21% | -$8.66K |
|
|
FNUC
3032
Frontier Nuclear and Minerals Inc
FNUC
$45.8M
| $21K | ﹤0.01% |
+3,142
| New | +$27.6K |
|
3033
Nexalin Technology
NXL
$7.14M
| $20.5K | ﹤0.01% |
10,498
-778
| -7% | -$2.13K |
|
|
SY
3034
So-Young International
SY
$239M
| $20.3K | ﹤0.01% |
24,473
-18
| -0.1% | -$17 |
|
|
SOWG
3035
Sow Good
SOWG
$62.2M
| $20.3K | ﹤0.01% |
1,339
-1,149
| -46% | -$43.6K |
|
|
ILLR
3036
Triller Group Inc
ILLR
$16.8M
| $20.2K | ﹤0.01% |
+2,591
| New | +$39K |
|
3037
Cheche Group
CCG
$42.2M
| $20.2K | ﹤0.01% |
679
-163
| -19% | -$5.53K |
|
|
JDZG
3038
JIADE Ltd
JDZG
$23.6M
| $19.9K | ﹤0.01% |
17
-3
| -15% | -$4.1K |
|
|
DGXX
3039
Digi Power X Inc
DGXX
$411M
| $19.9K | ﹤0.01% |
+17,476
| New | +$33.9K |
|
|
RVPH
3040
DELISTED
REVIVA PHARMA HLDGS INC
RVPH
| $19.7K | ﹤0.01% |
1,034
-24
| -2% | -$754 |
|
|
CMCT
3041
Creative Media & Community Trust
CMCT
$13.7M
| $19.2K | ﹤0.01% |
+31
| New | +$56.1K |
|
3042
FingerMotion
FNGR
$12M
| $19.1K | ﹤0.01% |
+13,934
| New | +$18K |
|
|
MRSN
3043
DELISTED
Mersana Therapeutics
MRSN
| $18.5K | ﹤0.01% |
2,146
-6,289
| -75% | -$97K |
|
3044
Arena Group
AREN
$46.4M
| $18K | ﹤0.01% |
10,400
-5,867
| -36% | -$8.59K |
|
3045
Zhongchao
ZCMD
$5.73M
| $17.7K | ﹤0.01% |
19
| – | – |
|
|
PCLA
3046
PicoCELA Inc
PCLA
$68.7M
| $17.7K | ﹤0.01% |
+1,034
| New | +$122K |
|
|
FRGE
3047
DELISTED
Forge Global Holdings
FRGE
| $17.7K | ﹤0.01% |
2,094
+479
| +30% | +$5.54K |
|
|
ALLK
3048
DELISTED
Allakos
ALLK
| $16.9K | ﹤0.01% |
74,270
+29,904
| +67% | +$13.5K |
|
3049
Passage Bio
PASG
$14.2M
| $16.6K | ﹤0.01% |
2,348
-120
| -5% | -$1.3K |
|
|
WBX
3050
Wallbox
WBX
$72.5M
| $16.5K | ﹤0.01% |
2,516
+1,387
| +123% | +$12.6K |
|
Similar funds
John Overdeck's Q1 2025 Portfolio in Review
As of Q1 2025, John Overdeck held 3,617 positions worth $46.8B, up 2% from $45.9B the previous quarter. Its ten largest holdings account for 8.1% of the portfolio.
John Overdeck deployed $2.08B of net new capital in Q1 2025, opening 458 new positions and adding to 1,225 existing holdings. Its largest new stake was Advanced Micro Devices: 2,246,952 shares worth $231M.
By sector, the portfolio is most concentrated in Technology at 18% of assets, up from 16% a quarter earlier, followed by Healthcare and Financials.
On the sell side, the largest reduction was Eli Lilly, an estimated $255M trimmed.
- John Overdeck's largest Q1 2025 buy was Advanced Micro Devices: 2,246,952 shares worth $231M.
- John Overdeck added most to State Street SPDR S&P 500 ETF Trust in Q1 2025, an estimated $510M increase.
- John Overdeck's biggest Q1 2025 reduction was Eli Lilly, cutting an estimated $255M.
- John Overdeck fully exited Coinbase in Q1 2025, selling an estimated $45M.
- John Overdeck's ten largest holdings make up 8.1% of its $46.8B portfolio in Q1 2025.
- John Overdeck opened 458 new positions and closed 452 in Q1 2025.
- John Overdeck's portfolio value rose 2% quarter-over-quarter to $46.8B.
Based on Two Sigma Investments's 13F filing for Q1 2025, filed 15 May 2025.