John Overdeck Two Sigma Investments
John Overdeck is a co-founder of Two Sigma Investments, one of the world’s leading quantitative and technology-driven investment firms. Two Sigma applies data science, machine learning, and large-scale computing to markets across asset classes. Overdeck’s firm is a central reference point in discussions of modern systematic investing.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
iShares Expanded Tech-Software Sector ETF
IGV
|
+$312M |
| 2 |
UnitedHealth
UNH
|
+$286M |
| 3 |
Duolingo
DUOL
|
+$247M |
| 4 |
Aon
AON
|
+$226M |
| 5 |
Chubb
CB
|
+$221M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Broadcom
AVGO
|
+$338M |
| 2 |
Marvell Technology
MRVL
|
+$241M |
| 3 |
Advanced Micro Devices
AMD
|
+$240M |
| 4 |
ServiceNow
NOW
|
+$203M |
| 5 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$193M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 16.79% |
| 2 | Financials | 14.46% |
| 3 | Healthcare | 12.9% |
| 4 | Consumer Discretionary | 8.97% |
| 5 | Industrials | 8.82% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
3001
Odyssey Marine Exploration
OMEX
$53.5M
| $43.5K | ﹤0.01% |
36,884
| – | – |
|
|
NOTV
3002
DELISTED
Inotiv
NOTV
| $43.3K | ﹤0.01% |
23,802
-26,882
| -53% | -$58.3K |
|
|
UNIT
3003
PUT
Uniti Group
UNIT
$2.38B
| $43.2K | ﹤0.01% |
10,000
| – | – |
|
3004
Greenland Technologies Holding
GTEC
$24.3M
| $42.6K | ﹤0.01% |
21,432
-591
| -3% | -$1.13K |
|
|
SGMA
3005
DELISTED
Sigmatron International
SGMA
| $42.2K | ﹤0.01% |
+14,180
| New | +$28.4K |
|
3006
ProKidney
PROK
$338M
| $41.9K | ﹤0.01% |
+70,699
| New | +$55K |
|
3007
Compass Therapeutics
CMPX
$430M
| $41.9K | ﹤0.01% |
16,097
-35,142
| -69% | -$72.5K |
|
|
ADVM
3008
DELISTED
Adverum Biotechnologies
ADVM
| $40.3K | ﹤0.01% |
+18,757
| New | +$52.5K |
|
|
BPT
3009
DELISTED
BP Prudhoe Bay Royalty Trust
BPT
| $39.1K | ﹤0.01% |
77,912
-22,585
| -22% | -$13.3K |
|
3010
SunCar Technology Group
SDA
$71.6M
| $38.1K | ﹤0.01% |
+14,948
| New | +$42.7K |
|
|
IRD
3011
Opus Genetics
IRD
$349M
| $37.9K | ﹤0.01% |
+40,190
| New | +$37.2K |
|
3012
SmartRent
SMRT
$268M
| $36K | ﹤0.01% |
+36,333
| New | +$32.5K |
|
3013
Arbutus Biopharma
ABUS
$1.03B
| $34.9K | ﹤0.01% |
11,299
-6,987
| -38% | -$23.2K |
|
3014
Castellum
CTM
$58.1M
| $34.6K | ﹤0.01% |
+32,996
| New | +$33.9K |
|
|
GBIO
3015
DELISTED
Generation Bio
GBIO
| $33.9K | ﹤0.01% |
10,596
+41
| +0.4% | +$158 |
|
3016
Maris-Tech
MTEK
$12M
| $33.8K | ﹤0.01% |
10,558
-9,677
| -48% | -$22.5K |
|
3017
BioAtla
BCAB
$5.8M
| $32.7K | ﹤0.01% |
1,652
-2,119
| -56% | -$43K |
|
|
BTOC
3018
Armlogi Holding Corp
BTOC
$13.6M
| $32.3K | ﹤0.01% |
19,968
-4,134
| -17% | -$5.37K |
|
|
LAR
3019
Lithium Argentina AG
LAR
$1.1B
| $32.3K | ﹤0.01% |
+15,527
| New | +$30.9K |
|
|
ARTV
3020
Artiva Biotherapeutics
ARTV
$557M
| $32.3K | ﹤0.01% |
+21,371
| New | +$44.9K |
|
3021
Celularity
CELU
$24.3M
| $31.8K | ﹤0.01% |
16,204
-20,176
| -55% | -$36.7K |
|
3022
Rekor Systems
REKR
$80.3M
| $29.8K | ﹤0.01% |
+25,680
| New | +$27K |
|
3023
Cognition Therapeutics
CGTX
$93.9M
| $29.5K | ﹤0.01% |
95,199
+12,655
| +15% | +$4.27K |
|
3024
Quince Therapeutics
QNCX
$34.1M
| $28.7K | ﹤0.01% |
87
-119
| -58% | -$27.2K |
|
3025
Smith Micro Software
SMSI
$16.5M
| $26.6K | ﹤0.01% |
6,162
+381
| +7% | +$1.71K |
|
Similar funds
John Overdeck's Q2 2025 Portfolio in Review
As of Q2 2025, John Overdeck held 3,681 positions worth $56.5B, up 21% from $46.8B the previous quarter. Its ten largest holdings account for 7.7% of the portfolio.
John Overdeck deployed $2.96B of net new capital in Q2 2025, opening 509 new positions and adding to 1,200 existing holdings. Its largest new stake was iShares Expanded Tech-Software Sector ETF: 3,154,300 shares worth $345M.
By sector, the portfolio is most concentrated in Technology at 17% of assets, down from 18% a quarter earlier, followed by Financials and Healthcare.
On the sell side, the largest reduction was Broadcom, an estimated $338M trimmed.
- John Overdeck's largest Q2 2025 buy was iShares Expanded Tech-Software Sector ETF: 3,154,300 shares worth $345M.
- John Overdeck added most to UnitedHealth in Q2 2025, an estimated $286M increase.
- John Overdeck's biggest Q2 2025 reduction was Broadcom, cutting an estimated $338M.
- John Overdeck fully exited State Street Utilities Select Sector SPDR ETF in Q2 2025, selling an estimated $134M.
- John Overdeck's ten largest holdings make up 7.7% of its $56.5B portfolio in Q2 2025.
- John Overdeck opened 509 new positions and closed 531 in Q2 2025.
- John Overdeck's portfolio value rose 21% quarter-over-quarter to $56.5B.
Based on Two Sigma Investments's 13F filing for Q2 2025, filed 14 Aug 2025.