John Overdeck Two Sigma Investments
John Overdeck is a co-founder of Two Sigma Investments, one of the world’s leading quantitative and technology-driven investment firms. Two Sigma applies data science, machine learning, and large-scale computing to markets across asset classes. Overdeck’s firm is a central reference point in discussions of modern systematic investing.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
iShares Expanded Tech-Software Sector ETF
IGV
|
+$312M |
| 2 |
UnitedHealth
UNH
|
+$286M |
| 3 |
Duolingo
DUOL
|
+$247M |
| 4 |
Aon
AON
|
+$226M |
| 5 |
Chubb
CB
|
+$221M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Broadcom
AVGO
|
+$338M |
| 2 |
Marvell Technology
MRVL
|
+$241M |
| 3 |
Advanced Micro Devices
AMD
|
+$240M |
| 4 |
ServiceNow
NOW
|
+$203M |
| 5 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$193M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 16.79% |
| 2 | Financials | 14.46% |
| 3 | Healthcare | 12.9% |
| 4 | Consumer Discretionary | 8.97% |
| 5 | Industrials | 8.82% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
|
FIRY
2901
Firy Inc
FIRY
$151M
| $125K | ﹤0.01% |
+18,307
| New | +$102K |
|
2902
Conduent
CNDT
$250M
| $124K | ﹤0.01% |
46,805
-117,626
| -72% | -$276K |
|
2903
Tactile Systems Technology
TCMD
$529M
| $122K | ﹤0.01% |
12,022
-47,256
| -80% | -$540K |
|
2904
Blink Charging
BLNK
$84.7M
| $120K | ﹤0.01% |
+127,352
| New | +$102K |
|
2905
Axogen
AXGN
$2.65B
| $119K | ﹤0.01% |
10,960
-152,888
| -93% | -$2M |
|
2906
Lionsgate Studios
LION
$3.44B
| $118K | ﹤0.01% |
20,330
-172,356
| -89% | -$1.15M |
|
|
IGMS
2907
DELISTED
IGM Biosciences
IGMS
| $117K | ﹤0.01% |
104,290
-35,480
| -25% | -$43.3K |
|
|
KZR
2908
DELISTED
Kezar Life Sciences
KZR
| $114K | ﹤0.01% |
24,883
-6,987
| -22% | -$30K |
|
2909
Tango Therapeutics
TNGX
$4.13B
| $114K | ﹤0.01% |
22,218
-30,684
| -58% | -$75.9K |
|
|
GAU
2910
Galiano Gold
GAU
$633M
| $109K | ﹤0.01% |
85,797
-68,303
| -44% | -$92.9K |
|
2911
Cumberland Pharmaceuticals
CPIX
$117M
| $108K | ﹤0.01% |
32,265
+9,510
| +42% | +$45K |
|
2912
electroCore
ECOR
$87M
| $108K | ﹤0.01% |
+20,372
| New | +$116K |
|
2913
Protalix BioTherapeutics
PLX
$194M
| $106K | ﹤0.01% |
71,537
-14,817
| -17% | -$30.3K |
|
2914
KVH Industries
KVHI
$136M
| $106K | ﹤0.01% |
19,813
-6,333
| -24% | -$32.7K |
|
2915
Stem
STEM
$52.6M
| $104K | ﹤0.01% |
16,738
+6,332
| +61% | +$56.8K |
|
|
SHCO
2916
DELISTED
Soho House & Co
SHCO
| $104K | ﹤0.01% |
14,096
-2
| -0% | -$12 |
|
2917
NRX Pharmaceuticals
NRXP
$149M
| $103K | ﹤0.01% |
31,452
+1,306
| +4% | +$3.27K |
|
2918
Custom Truck One Source
CTOS
$2.22B
| $102K | ﹤0.01% |
20,696
+3,248
| +19% | +$14K |
|
|
LUXE
2919
LuxExperience B.V.
LUXE
$1.07B
| $101K | ﹤0.01% |
12,762
-20,707
| -62% | -$172K |
|
2920
Cosan
CSAN
$2.64B
| $101K | ﹤0.01% |
20,049
-2,600
| -11% | -$14K |
|
|
CSAI
2921
Cloudastructure
CSAI
$4.46M
| $101K | ﹤0.01% |
+1,527
| New | +$159K |
|
|
ONL
2922
Orion Office REIT
ONL
$166M
| $101K | ﹤0.01% |
47,368
-12,660
| -21% | -$24.1K |
|
2923
Sagimet Biosciences
SGMT
$635M
| $99.4K | ﹤0.01% |
13,045
-36,804
| -74% | -$155K |
|
2924
Alto Neuroscience
ANRO
$1.42B
| $98.4K | ﹤0.01% |
44,735
+18,593
| +71% | +$44.2K |
|
|
ILPT
2925
Industrial Logistics Properties Trust
ILPT
$562M
| $98.3K | ﹤0.01% |
21,600
-40,401
| -65% | -$134K |
|
Similar funds
John Overdeck's Q2 2025 Portfolio in Review
As of Q2 2025, John Overdeck held 3,681 positions worth $56.5B, up 21% from $46.8B the previous quarter. Its ten largest holdings account for 7.7% of the portfolio.
John Overdeck deployed $2.96B of net new capital in Q2 2025, opening 509 new positions and adding to 1,200 existing holdings. Its largest new stake was iShares Expanded Tech-Software Sector ETF: 3,154,300 shares worth $345M.
By sector, the portfolio is most concentrated in Technology at 17% of assets, down from 18% a quarter earlier, followed by Financials and Healthcare.
On the sell side, the largest reduction was Broadcom, an estimated $338M trimmed.
- John Overdeck's largest Q2 2025 buy was iShares Expanded Tech-Software Sector ETF: 3,154,300 shares worth $345M.
- John Overdeck added most to UnitedHealth in Q2 2025, an estimated $286M increase.
- John Overdeck's biggest Q2 2025 reduction was Broadcom, cutting an estimated $338M.
- John Overdeck fully exited State Street Utilities Select Sector SPDR ETF in Q2 2025, selling an estimated $134M.
- John Overdeck's ten largest holdings make up 7.7% of its $56.5B portfolio in Q2 2025.
- John Overdeck opened 509 new positions and closed 531 in Q2 2025.
- John Overdeck's portfolio value rose 21% quarter-over-quarter to $56.5B.
Based on Two Sigma Investments's 13F filing for Q2 2025, filed 14 Aug 2025.