John Overdeck Two Sigma Investments
John Overdeck is a co-founder of Two Sigma Investments, one of the world’s leading quantitative and technology-driven investment firms. Two Sigma applies data science, machine learning, and large-scale computing to markets across asset classes. Overdeck’s firm is a central reference point in discussions of modern systematic investing.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street Financial Select Sector SPDR ETF
XLF
|
+$474M |
| 2 |
State Street Consumer Staples Select Sector SPDR ETF
XLP
|
+$357M |
| 3 |
Accenture
ACN
|
+$246M |
| 4 |
Advanced Micro Devices
AMD
|
+$235M |
| 5 |
State Street SPDR Dow Jones Industrial Average ETF Trust
DIA
|
+$231M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Invesco QQQ Trust
QQQ
|
+$381M |
| 2 |
State Street Technology Select Sector SPDR ETF
XLK
|
+$375M |
| 3 |
iShares Expanded Tech-Software Sector ETF
IGV
|
+$348M |
| 4 |
Thermo Fisher Scientific
TMO
|
+$292M |
| 5 |
Snowflake
SNOW
|
+$258M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 16.18% |
| 2 | Financials | 15.54% |
| 3 | Industrials | 10.5% |
| 4 | Healthcare | 9.8% |
| 5 | Consumer Discretionary | 8.1% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
2851
Lexeo Therapeutics
LXEO
$404M
| $563K | ﹤0.01% |
84,763
+15,521
| +22% | +$75.1K |
|
|
WCBR
2852
WisdomTree Cybersecurity Fund
WCBR
$127M
| $562K | ﹤0.01% |
17,900
-22,600
| -56% | -$697K |
|
2853
Tilly's
TLYS
$114M
| $561K | ﹤0.01% |
272,496
+142,165
| +109% | +$246K |
|
|
GPMT
2854
Granite Point Mortgage Trust
GPMT
$52.5M
| $560K | ﹤0.01% |
+186,781
| New | +$516K |
|
2855
MillerKnoll
MLKN
$1.58B
| $560K | ﹤0.01% |
+31,563
| New | +$639K |
|
2856
PUT
TSMC
TSM
$2.13T
| $559K | ﹤0.01% |
+2,000
| New | +$489K |
|
2857
Vanguard Russell 1000 Growth ETF
VONG
$44.5B
| $554K | ﹤0.01% |
4,600
-865,600
| -99% | -$99.2M |
|
2858
CALL
Roblox
RBLX
$27.7B
| $554K | ﹤0.01% |
+4,000
| New | +$497K |
|
2859
iShares Core S&P Total US Stock Market ETF
ITOT
$96.8B
| $553K | ﹤0.01% |
3,800
-162,800
| -98% | -$22.8M |
|
2860
First Bank
FRBA
$449M
| $553K | ﹤0.01% |
33,950
-14,790
| -30% | -$237K |
|
|
ACRE
2861
Ares Commercial Real Estate
ACRE
$262M
| $552K | ﹤0.01% |
122,425
+92,002
| +302% | +$427K |
|
2862
Jazz Pharmaceuticals
JAZZ
$16.5B
| $550K | ﹤0.01% |
4,173
-40,939
| -91% | -$4.91M |
|
|
ORKA
2863
Oruka Therapeutics
ORKA
$6.78B
| $549K | ﹤0.01% |
28,566
-3,776
| -12% | -$56K |
|
2864
Limoneira
LMNR
$254M
| $548K | ﹤0.01% |
36,884
+16,788
| +84% | +$260K |
|
2865
Neumora Therapeutics
NMRA
$287M
| $546K | ﹤0.01% |
299,814
-288,518
| -49% | -$466K |
|
|
IA
2866
Innovative Solutions & Support
IA
$375M
| $545K | ﹤0.01% |
+43,637
| New | +$609K |
|
2867
CPI Card Group
PMTS
$329M
| $545K | ﹤0.01% |
35,989
-5,142
| -13% | -$91.4K |
|
2868
Five Point Holdings
FPH
$371M
| $542K | ﹤0.01% |
88,361
-18,770
| -18% | -$109K |
|
2869
Resources Connection
RGP
$147M
| $541K | ﹤0.01% |
107,111
+93,190
| +669% | +$479K |
|
2870
Entrada Therapeutics
TRDA
$285M
| $541K | ﹤0.01% |
+93,194
| New | +$545K |
|
2871
NACCO Industries
NC
$309M
| $540K | ﹤0.01% |
12,816
-2,683
| -17% | -$106K |
|
2872
Cineverse
CNVS
$60.4M
| $540K | ﹤0.01% |
160,631
+131,416
| +450% | +$653K |
|
2873
CALL
Fastenal
FAST
$58.8B
| $539K | ﹤0.01% |
+11,000
| New | +$520K |
|
2874
PUT
O'Reilly Automotive
ORLY
$73.4B
| $539K | ﹤0.01% |
+5,000
| New | +$503K |
|
2875
American Eagle Outfitters
AEO
$2.83B
| $537K | ﹤0.01% |
31,387
-772,041
| -96% | -$10.6M |
|
Similar funds
John Overdeck's Q3 2025 Portfolio in Review
As of Q3 2025, John Overdeck held 4,027 positions worth $67.2B, up 19% from $56.5B the previous quarter. Its ten largest holdings account for 6.2% of the portfolio.
John Overdeck deployed $4.46B of net new capital in Q3 2025, opening 877 new positions and adding to 1,461 existing holdings. Its largest new stake was Berkshire Hathaway Class B: 379,096 shares worth $191M.
By sector, the portfolio is most concentrated in Technology at 16% of assets, down from 17% a quarter earlier, followed by Financials and Industrials.
On the sell side, the largest reduction was Invesco QQQ Trust, an estimated $381M trimmed.
- John Overdeck's largest Q3 2025 buy was Berkshire Hathaway Class B: 379,096 shares worth $191M.
- John Overdeck added most to State Street Financial Select Sector SPDR ETF in Q3 2025, an estimated $474M increase.
- John Overdeck's biggest Q3 2025 reduction was Invesco QQQ Trust, cutting an estimated $381M.
- John Overdeck fully exited NextEra Energy, Inc. 6.926% Corporate Units in Q3 2025, selling an estimated $115M.
- John Overdeck's ten largest holdings make up 6.2% of its $67.2B portfolio in Q3 2025.
- John Overdeck opened 877 new positions and closed 399 in Q3 2025.
- John Overdeck's portfolio value rose 19% quarter-over-quarter to $67.2B.
Based on Two Sigma Investments's 13F filing for Q3 2025, filed 14 Nov 2025.