John Overdeck Two Sigma Investments
John Overdeck is a co-founder of Two Sigma Investments, one of the world’s leading quantitative and technology-driven investment firms. Two Sigma applies data science, machine learning, and large-scale computing to markets across asset classes. Overdeck’s firm is a central reference point in discussions of modern systematic investing.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street Financial Select Sector SPDR ETF
XLF
|
+$474M |
| 2 |
State Street Consumer Staples Select Sector SPDR ETF
XLP
|
+$357M |
| 3 |
Accenture
ACN
|
+$246M |
| 4 |
Advanced Micro Devices
AMD
|
+$235M |
| 5 |
State Street SPDR Dow Jones Industrial Average ETF Trust
DIA
|
+$231M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Invesco QQQ Trust
QQQ
|
+$381M |
| 2 |
State Street Technology Select Sector SPDR ETF
XLK
|
+$375M |
| 3 |
iShares Expanded Tech-Software Sector ETF
IGV
|
+$348M |
| 4 |
Thermo Fisher Scientific
TMO
|
+$292M |
| 5 |
Snowflake
SNOW
|
+$258M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 16.18% |
| 2 | Financials | 15.54% |
| 3 | Industrials | 10.5% |
| 4 | Healthcare | 9.8% |
| 5 | Consumer Discretionary | 8.1% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
2826
Zura Bio
ZURA
$604M
| $590K | ﹤0.01% |
136,303
-108,622
| -44% | -$195K |
|
2827
Korn Ferry
KFY
$4.35B
| $590K | ﹤0.01% |
+8,426
| New | +$615K |
|
2828
Travelzoo
TZOO
$69M
| $590K | ﹤0.01% |
59,975
-16,949
| -22% | -$182K |
|
2829
Fastenal
FAST
$58.8B
| $588K | ﹤0.01% |
12,000
-26,161
| -69% | -$1.24M |
|
2830
PUT
Trade Desk
TTD
$6.24B
| $588K | ﹤0.01% |
+12,000
| New | +$761K |
|
2831
ChargePoint
CHPT
$153M
| $588K | ﹤0.01% |
53,851
-12,522
| -19% | -$143K |
|
|
BIOA
2832
BioAge Labs
BIOA
$431M
| $586K | ﹤0.01% |
99,669
+35,068
| +54% | +$164K |
|
2833
CALL
Boston Scientific
BSX
$71B
| $586K | ﹤0.01% |
+6,000
| New | +$621K |
|
2834
Castle Biosciences
CSTL
$1.02B
| $585K | ﹤0.01% |
25,700
-2,541
| -9% | -$51.6K |
|
2835
Invesco S&P 500 Equal Weight Financials ETF
RSPF
$317M
| $583K | ﹤0.01% |
7,500
-400
| -5% | -$30.9K |
|
2836
National Grid
NGG
$80.9B
| $581K | ﹤0.01% |
+8,114
| New | +$569K |
|
2837
Nurix Therapeutics
NRIX
$2.73B
| $581K | ﹤0.01% |
62,875
-95,849
| -60% | -$995K |
|
|
FSP
2838
Franklin Street Properties
FSP
$48.2M
| $581K | ﹤0.01% |
363,102
+102,289
| +39% | +$169K |
|
2839
Commercial Vehicle Group
CVGI
$124M
| $579K | ﹤0.01% |
340,877
-71,043
| -17% | -$130K |
|
2840
Ingersoll Rand
IR
$31B
| $578K | ﹤0.01% |
+7,000
| New | +$574K |
|
2841
Acrivon Therapeutics
ACRV
$94.3M
| $578K | ﹤0.01% |
319,205
+138,033
| +76% | +$194K |
|
2842
Lantronix
LTRX
$256M
| $578K | ﹤0.01% |
126,376
-56,170
| -31% | -$208K |
|
2843
Vuzix
VUZI
$235M
| $576K | ﹤0.01% |
183,882
-78,027
| -30% | -$184K |
|
2844
Grid Dynamics Holdings
GDYN
$638M
| $575K | ﹤0.01% |
74,588
-206,524
| -73% | -$1.84M |
|
2845
Schwab U.S Small- Cap ETF
SCHA
$22.8B
| $569K | ﹤0.01% |
+20,400
| New | +$545K |
|
|
LOMA
2846
Loma Negra
LOMA
$1.12B
| $569K | ﹤0.01% |
77,175
-68,798
| -47% | -$684K |
|
2847
Papa John's
PZZA
$793M
| $569K | ﹤0.01% |
11,812
-19,378
| -62% | -$897K |
|
2848
Savara
SVRA
$1.14B
| $564K | ﹤0.01% |
158,016
-124,748
| -44% | -$369K |
|
2849
Trip.com Group
TCOM
$29B
| $564K | ﹤0.01% |
+7,500
| New | +$501K |
|
2850
Azenta
AZTA
$1.44B
| $563K | ﹤0.01% |
19,600
+12,293
| +168% | +$381K |
|
Similar funds
John Overdeck's Q3 2025 Portfolio in Review
As of Q3 2025, John Overdeck held 4,027 positions worth $67.2B, up 19% from $56.5B the previous quarter. Its ten largest holdings account for 6.2% of the portfolio.
John Overdeck deployed $4.46B of net new capital in Q3 2025, opening 877 new positions and adding to 1,461 existing holdings. Its largest new stake was Berkshire Hathaway Class B: 379,096 shares worth $191M.
By sector, the portfolio is most concentrated in Technology at 16% of assets, down from 17% a quarter earlier, followed by Financials and Industrials.
On the sell side, the largest reduction was Invesco QQQ Trust, an estimated $381M trimmed.
- John Overdeck's largest Q3 2025 buy was Berkshire Hathaway Class B: 379,096 shares worth $191M.
- John Overdeck added most to State Street Financial Select Sector SPDR ETF in Q3 2025, an estimated $474M increase.
- John Overdeck's biggest Q3 2025 reduction was Invesco QQQ Trust, cutting an estimated $381M.
- John Overdeck fully exited NextEra Energy, Inc. 6.926% Corporate Units in Q3 2025, selling an estimated $115M.
- John Overdeck's ten largest holdings make up 6.2% of its $67.2B portfolio in Q3 2025.
- John Overdeck opened 877 new positions and closed 399 in Q3 2025.
- John Overdeck's portfolio value rose 19% quarter-over-quarter to $67.2B.
Based on Two Sigma Investments's 13F filing for Q3 2025, filed 14 Nov 2025.