John Overdeck Two Sigma Investments
John Overdeck is a co-founder of Two Sigma Investments, one of the world’s leading quantitative and technology-driven investment firms. Two Sigma applies data science, machine learning, and large-scale computing to markets across asset classes. Overdeck’s firm is a central reference point in discussions of modern systematic investing.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$510M |
| 2 |
Broadcom
AVGO
|
+$318M |
| 3 |
Marvell Technology
MRVL
|
+$290M |
| 4 |
Salesforce
CRM
|
+$263M |
| 5 |
Advanced Micro Devices
AMD
|
+$250M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Eli Lilly
LLY
|
+$255M |
| 2 |
Progressive
PGR
|
+$244M |
| 3 |
Visa
V
|
+$238M |
| 4 |
Lam Research
LRCX
|
+$201M |
| 5 |
Elevance Health
ELV
|
+$190M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 17.88% |
| 2 | Healthcare | 13.28% |
| 3 | Financials | 10.32% |
| 4 | Industrials | 9.79% |
| 5 | Consumer Discretionary | 8.58% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
2801
CarParts.com
PRTS
$50.5M
| $185K | ﹤0.01% |
18,539
-17,341
| -48% | -$190K |
|
2802
Cardlytics
CDLX
$25.2M
| $185K | ﹤0.01% |
10,159
+669
| +7% | +$19.1K |
|
|
KYNB
2803
Kyntra Bio
KYNB
$32.3M
| $181K | ﹤0.01% |
23,378
-799
| -3% | -$9.58K |
|
2804
Liberty Energy
LBRT
$3.02B
| $181K | ﹤0.01% |
11,422
-156,450
| -93% | -$2.81M |
|
2805
Sana Biotechnology
SANA
$1.13B
| $181K | ﹤0.01% |
107,486
-372,812
| -78% | -$1.04M |
|
2806
SelectQuote
SLQT
$137M
| $180K | ﹤0.01% |
54,031
-186,466
| -78% | -$791K |
|
2807
Outset Medical
OM
$78.8M
| $180K | ﹤0.01% |
16,288
-16,285
| -50% | -$194K |
|
2808
RE/MAX Holdings
RMAX
$263M
| $180K | ﹤0.01% |
21,479
-29,026
| -57% | -$277K |
|
|
RPC
2809
Ridgepost Capital
RPC
$980M
| $179K | ﹤0.01% |
15,217
-147,627
| -91% | -$1.88M |
|
2810
Hallador Energy
HNRG
$752M
| $178K | ﹤0.01% |
14,509
-5,022
| -26% | -$56.4K |
|
2811
Pangaea Logistics
PANL
$547M
| $176K | ﹤0.01% |
36,945
-47,780
| -56% | -$252K |
|
|
CMRC
2812
Commerce.com Inc Series 1
CMRC
$186M
| $174K | ﹤0.01% |
30,244
-136,043
| -82% | -$864K |
|
2813
Repay Holdings
RPAY
$318M
| $174K | ﹤0.01% |
31,166
-175,201
| -85% | -$1.21M |
|
|
NBP
2814
NovaBridge Biosciences American Depositary Shares
NBP
$219M
| $173K | ﹤0.01% |
210,366
-119,840
| -36% | -$114K |
|
|
NESR
2815
National Energy Services Reunited Corp
NESR
$3.37B
| $173K | ﹤0.01% |
23,539
-19,017
| -45% | -$164K |
|
2816
CorMedix
CRMD
$645M
| $172K | ﹤0.01% |
27,950
-3,539
| -11% | -$36.6K |
|
2817
Children's Place
PLCE
$58M
| $170K | ﹤0.01% |
19,472
-86,004
| -82% | -$801K |
|
2818
Sundial Growers
SNDL
$338M
| $169K | ﹤0.01% |
119,950
-167,866
| -58% | -$285K |
|
2819
CareCloud
CCLD
$106M
| $167K | ﹤0.01% |
120,091
+96,998
| +420% | +$286K |
|
|
THRD
2820
DELISTED
Third Harmonic Bio
THRD
| $167K | ﹤0.01% |
+48,029
| New | +$233K |
|
|
BCAX
2821
Bicara Therapeutics
BCAX
$1.56B
| $166K | ﹤0.01% |
+12,770
| New | +$170K |
|
2822
Alto Ingredients
ALTO
$325M
| $166K | ﹤0.01% |
145,680
-12,579
| -8% | -$19.5K |
|
2823
LifeMD
LFMD
$151M
| $165K | ﹤0.01% |
+30,400
| New | +$172K |
|
2824
Ondas Inc
ONDS
$4.7B
| $165K | ﹤0.01% |
154,200
+142,056
| +1,170% | +$213K |
|
2825
Rimini Street
RMNI
$486M
| $164K | ﹤0.01% |
47,250
-41,526
| -47% | -$135K |
|
Similar funds
John Overdeck's Q1 2025 Portfolio in Review
As of Q1 2025, John Overdeck held 3,617 positions worth $46.8B, up 2% from $45.9B the previous quarter. Its ten largest holdings account for 8.1% of the portfolio.
John Overdeck deployed $2.08B of net new capital in Q1 2025, opening 458 new positions and adding to 1,225 existing holdings. Its largest new stake was Advanced Micro Devices: 2,246,952 shares worth $231M.
By sector, the portfolio is most concentrated in Technology at 18% of assets, up from 16% a quarter earlier, followed by Healthcare and Financials.
On the sell side, the largest reduction was Eli Lilly, an estimated $255M trimmed.
- John Overdeck's largest Q1 2025 buy was Advanced Micro Devices: 2,246,952 shares worth $231M.
- John Overdeck added most to State Street SPDR S&P 500 ETF Trust in Q1 2025, an estimated $510M increase.
- John Overdeck's biggest Q1 2025 reduction was Eli Lilly, cutting an estimated $255M.
- John Overdeck fully exited Coinbase in Q1 2025, selling an estimated $45M.
- John Overdeck's ten largest holdings make up 8.1% of its $46.8B portfolio in Q1 2025.
- John Overdeck opened 458 new positions and closed 452 in Q1 2025.
- John Overdeck's portfolio value rose 2% quarter-over-quarter to $46.8B.
Based on Two Sigma Investments's 13F filing for Q1 2025, filed 15 May 2025.