John Overdeck Two Sigma Investments
John Overdeck is a co-founder of Two Sigma Investments, one of the world’s leading quantitative and technology-driven investment firms. Two Sigma applies data science, machine learning, and large-scale computing to markets across asset classes. Overdeck’s firm is a central reference point in discussions of modern systematic investing.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$510M |
| 2 |
Broadcom
AVGO
|
+$318M |
| 3 |
Marvell Technology
MRVL
|
+$290M |
| 4 |
Salesforce
CRM
|
+$263M |
| 5 |
Advanced Micro Devices
AMD
|
+$250M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Eli Lilly
LLY
|
+$255M |
| 2 |
Progressive
PGR
|
+$244M |
| 3 |
Visa
V
|
+$238M |
| 4 |
Lam Research
LRCX
|
+$201M |
| 5 |
Elevance Health
ELV
|
+$190M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 17.88% |
| 2 | Healthcare | 13.28% |
| 3 | Financials | 10.32% |
| 4 | Industrials | 9.79% |
| 5 | Consumer Discretionary | 8.58% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
2751
Stewart Information Services
STC
$2.13B
| $225K | ﹤0.01% |
3,151
-561
| -15% | -$38K |
|
|
ORKA
2752
Oruka Therapeutics
ORKA
$6.78B
| $224K | ﹤0.01% |
+21,831
| New | +$272K |
|
2753
Tucows
TCX
$104M
| $223K | ﹤0.01% |
+13,233
| New | +$230K |
|
2754
Consolidated Water Co
CWCO
$479M
| $223K | ﹤0.01% |
+9,117
| New | +$243K |
|
2755
Hyliion Holdings
HYLN
$563M
| $223K | ﹤0.01% |
158,947
+101,347
| +176% | +$201K |
|
2756
First Trust Dow Jones Internet Index Fund ETF
FDN
$5.29B
| $222K | ﹤0.01% |
1,000
-61,600
| -98% | -$15.2M |
|
2757
Protalix BioTherapeutics
PLX
$194M
| $221K | ﹤0.01% |
+86,354
| New | +$206K |
|
|
CNTA
2758
DELISTED
Centessa Pharmaceuticals
CNTA
| $220K | ﹤0.01% |
15,300
-22,600
| -60% | -$370K |
|
2759
Thor Industries
THO
$4.13B
| $220K | ﹤0.01% |
+2,900
| New | +$273K |
|
2760
Boston Beer
SAM
$1.95B
| $219K | ﹤0.01% |
916
-23,113
| -96% | -$5.63M |
|
2761
Lineage Cell Therapeutics
LCTX
$276M
| $217K | ﹤0.01% |
480,423
+178,879
| +59% | +$105K |
|
|
SLN
2762
Silence Therapeutics
SLN
$826M
| $214K | ﹤0.01% |
76,008
-66,044
| -46% | -$322K |
|
|
LENZ
2763
LENZ Therapeutics
LENZ
$144M
| $214K | ﹤0.01% |
8,322
-8,757
| -51% | -$216K |
|
|
NOTE
2764
DELISTED
FiscalNote
NOTE
| $214K | ﹤0.01% |
+22,036
| New | +$331K |
|
2765
Invesco Bloomberg Pricing Power ETF
POWA
$179M
| $214K | ﹤0.01% |
+2,600
| New | +$216K |
|
|
ILPT
2766
Industrial Logistics Properties Trust
ILPT
$562M
| $213K | ﹤0.01% |
62,001
+801
| +1% | +$2.99K |
|
|
FLOC
2767
Flowco Holdings
FLOC
$948M
| $213K | ﹤0.01% |
+8,300
| New | +$219K |
|
|
HIVE
2768
HIVE Digital Technologies
HIVE
$784M
| $211K | ﹤0.01% |
145,485
-561,420
| -79% | -$1.38M |
|
2769
Cognyte Software
CGNT
$631M
| $211K | ﹤0.01% |
+27,044
| New | +$246K |
|
2770
Tenaya Therapeutics
TNYA
$151M
| $210K | ﹤0.01% |
367,629
+322,858
| +721% | +$319K |
|
2771
MVB Financial
MVBF
$392M
| $209K | ﹤0.01% |
12,047
-10,362
| -46% | -$195K |
|
2772
Lyell Immunopharma
LYEL
$361M
| $209K | ﹤0.01% |
19,384
+9,159
| +90% | +$112K |
|
2773
Transcat
TRNS
$818M
| $208K | ﹤0.01% |
2,799
-2,474
| -47% | -$207K |
|
2774
Corteva
CTVA
$55.3B
| $208K | ﹤0.01% |
3,308
-14,400
| -81% | -$890K |
|
|
KRMN
2775
Karman Holdings
KRMN
$6.81B
| $208K | ﹤0.01% |
+6,220
| New | +$201K |
|
Similar funds
John Overdeck's Q1 2025 Portfolio in Review
As of Q1 2025, John Overdeck held 3,617 positions worth $46.8B, up 2% from $45.9B the previous quarter. Its ten largest holdings account for 8.1% of the portfolio.
John Overdeck deployed $2.08B of net new capital in Q1 2025, opening 458 new positions and adding to 1,225 existing holdings. Its largest new stake was Advanced Micro Devices: 2,246,952 shares worth $231M.
By sector, the portfolio is most concentrated in Technology at 18% of assets, up from 16% a quarter earlier, followed by Healthcare and Financials.
On the sell side, the largest reduction was Eli Lilly, an estimated $255M trimmed.
- John Overdeck's largest Q1 2025 buy was Advanced Micro Devices: 2,246,952 shares worth $231M.
- John Overdeck added most to State Street SPDR S&P 500 ETF Trust in Q1 2025, an estimated $510M increase.
- John Overdeck's biggest Q1 2025 reduction was Eli Lilly, cutting an estimated $255M.
- John Overdeck fully exited Coinbase in Q1 2025, selling an estimated $45M.
- John Overdeck's ten largest holdings make up 8.1% of its $46.8B portfolio in Q1 2025.
- John Overdeck opened 458 new positions and closed 452 in Q1 2025.
- John Overdeck's portfolio value rose 2% quarter-over-quarter to $46.8B.
Based on Two Sigma Investments's 13F filing for Q1 2025, filed 15 May 2025.