John Overdeck Two Sigma Investments
John Overdeck is a co-founder of Two Sigma Investments, one of the world’s leading quantitative and technology-driven investment firms. Two Sigma applies data science, machine learning, and large-scale computing to markets across asset classes. Overdeck’s firm is a central reference point in discussions of modern systematic investing.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$510M |
| 2 |
Broadcom
AVGO
|
+$318M |
| 3 |
Marvell Technology
MRVL
|
+$290M |
| 4 |
Salesforce
CRM
|
+$263M |
| 5 |
Advanced Micro Devices
AMD
|
+$250M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Eli Lilly
LLY
|
+$255M |
| 2 |
Progressive
PGR
|
+$244M |
| 3 |
Visa
V
|
+$238M |
| 4 |
Lam Research
LRCX
|
+$201M |
| 5 |
Elevance Health
ELV
|
+$190M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 17.88% |
| 2 | Healthcare | 13.28% |
| 3 | Financials | 10.32% |
| 4 | Industrials | 9.79% |
| 5 | Consumer Discretionary | 8.58% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
2651
Microvision
MVIS
$52M
| $302K | ﹤0.01% |
16,211
+2,618
| +19% | +$54.7K |
|
2652
ETC 6 Meridian Small Cap Equity ETF
SIXS
$146M
| $300K | ﹤0.01% |
+6,400
| New | +$311K |
|
2653
Kodiak Sciences
KOD
$2.34B
| $299K | ﹤0.01% |
106,664
+57,258
| +116% | +$311K |
|
2654
InfuSystem Holdings
INFU
$238M
| $297K | ﹤0.01% |
55,287
+19,035
| +53% | +$139K |
|
2655
Eos Energy Enterprises
EOSE
$1.26B
| $296K | ﹤0.01% |
+78,389
| New | +$382K |
|
2656
FTAI Infrastructure
FIP
$443M
| $295K | ﹤0.01% |
65,211
-214,816
| -77% | -$1.34M |
|
2657
Ligand Pharmaceuticals
LGND
$5.59B
| $294K | ﹤0.01% |
2,800
-207
| -7% | -$23.4K |
|
2658
Lithia Motors
LAD
$8.1B
| $294K | ﹤0.01% |
1,000
| – | – |
|
2659
Kopin
KOPN
$881M
| $293K | ﹤0.01% |
314,363
-247,674
| -44% | -$364K |
|
2660
HighPeak Energy
HPK
$1.03B
| $292K | ﹤0.01% |
23,091
-35,786
| -61% | -$481K |
|
2661
Superior Group of Companies
SGC
$203M
| $291K | ﹤0.01% |
26,633
+2,980
| +13% | +$41.9K |
|
2662
Fidelity Fundamental Large Cap Growth ETF
FFLG
$606M
| $290K | ﹤0.01% |
13,100
-59,000
| -82% | -$1.46M |
|
|
CKPT
2663
DELISTED
Checkpoint Therapeutics
CKPT
| $290K | ﹤0.01% |
71,727
-1,305
| -2% | -$4.35K |
|
2664
Entravision Communication
EVC
$748M
| $289K | ﹤0.01% |
137,632
-4,481
| -3% | -$9.8K |
|
2665
Cars.com
CARS
$662M
| $287K | ﹤0.01% |
25,502
-108,976
| -81% | -$1.66M |
|
2666
Energy Services of America
ESOA
$215M
| $287K | ﹤0.01% |
30,346
+10,146
| +50% | +$111K |
|
2667
Republic Bancorp
RBCAA
$1.86B
| $286K | ﹤0.01% |
4,476
+894
| +25% | +$59.3K |
|
2668
NRC Health Common Stock
NRC
$485M
| $285K | ﹤0.01% |
22,265
-19,426
| -47% | -$312K |
|
2669
iShares Silver Trust
SLV
$33.5B
| $285K | ﹤0.01% |
+9,194
| New | +$267K |
|
|
MZTI
2670
The Marzetti Company
MZTI
$3.17B
| $285K | ﹤0.01% |
+1,626
| New | +$293K |
|
2671
State Street SPDR S&P Retail ETF
XRT
$329M
| $283K | ﹤0.01% |
+4,100
| New | +$310K |
|
|
MTLS
2672
Materialise
MTLS
$387M
| $283K | ﹤0.01% |
57,569
-23,701
| -29% | -$163K |
|
|
WCC
2673
WESCO International
WCC
$16.4B
| $282K | ﹤0.01% |
1,813
-209
| -10% | -$37.4K |
|
2674
VistaGen Therapeutics
VTGN
$10.8M
| $281K | ﹤0.01% |
112,507
-24,827
| -18% | -$70.3K |
|
2675
State Street SPDR S&P Transportation ETF
XTN
$371M
| $281K | ﹤0.01% |
3,800
-35,200
| -90% | -$2.96M |
|
Similar funds
John Overdeck's Q1 2025 Portfolio in Review
As of Q1 2025, John Overdeck held 3,617 positions worth $46.8B, up 2% from $45.9B the previous quarter. Its ten largest holdings account for 8.1% of the portfolio.
John Overdeck deployed $2.08B of net new capital in Q1 2025, opening 458 new positions and adding to 1,225 existing holdings. Its largest new stake was Advanced Micro Devices: 2,246,952 shares worth $231M.
By sector, the portfolio is most concentrated in Technology at 18% of assets, up from 16% a quarter earlier, followed by Healthcare and Financials.
On the sell side, the largest reduction was Eli Lilly, an estimated $255M trimmed.
- John Overdeck's largest Q1 2025 buy was Advanced Micro Devices: 2,246,952 shares worth $231M.
- John Overdeck added most to State Street SPDR S&P 500 ETF Trust in Q1 2025, an estimated $510M increase.
- John Overdeck's biggest Q1 2025 reduction was Eli Lilly, cutting an estimated $255M.
- John Overdeck fully exited Coinbase in Q1 2025, selling an estimated $45M.
- John Overdeck's ten largest holdings make up 8.1% of its $46.8B portfolio in Q1 2025.
- John Overdeck opened 458 new positions and closed 452 in Q1 2025.
- John Overdeck's portfolio value rose 2% quarter-over-quarter to $46.8B.
Based on Two Sigma Investments's 13F filing for Q1 2025, filed 15 May 2025.