John Overdeck Two Sigma Investments
John Overdeck is a co-founder of Two Sigma Investments, one of the world’s leading quantitative and technology-driven investment firms. Two Sigma applies data science, machine learning, and large-scale computing to markets across asset classes. Overdeck’s firm is a central reference point in discussions of modern systematic investing.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
iShares Expanded Tech-Software Sector ETF
IGV
|
+$312M |
| 2 |
UnitedHealth
UNH
|
+$286M |
| 3 |
Duolingo
DUOL
|
+$247M |
| 4 |
Aon
AON
|
+$226M |
| 5 |
Chubb
CB
|
+$221M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Broadcom
AVGO
|
+$338M |
| 2 |
Marvell Technology
MRVL
|
+$241M |
| 3 |
Advanced Micro Devices
AMD
|
+$240M |
| 4 |
ServiceNow
NOW
|
+$203M |
| 5 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$193M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 16.79% |
| 2 | Financials | 14.46% |
| 3 | Healthcare | 12.9% |
| 4 | Consumer Discretionary | 8.97% |
| 5 | Industrials | 8.82% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
|
EPIX
2626
DELISTED
ESSA Pharma
EPIX
| $378K | ﹤0.01% |
222,327
-56,793
| -20% | -$95.8K |
|
2627
Trupanion
TRUP
$1.39B
| $376K | ﹤0.01% |
6,799
-112,739
| -94% | -$4.99M |
|
2628
Safe Bulkers
SB
$881M
| $375K | ﹤0.01% |
104,005
-1,942
| -2% | -$6.95K |
|
2629
Personalis
PSNL
$1.82B
| $373K | ﹤0.01% |
56,893
-53,313
| -48% | -$247K |
|
2630
Haleon
HLN
$44.7B
| $372K | ﹤0.01% |
35,837
-79,800
| -69% | -$842K |
|
2631
Dana Inc
DAN
$3.24B
| $371K | ﹤0.01% |
21,645
-47,723
| -69% | -$712K |
|
2632
Kyverna Therapeutics
KYTX
$510M
| $370K | ﹤0.01% |
120,584
-2,393
| -2% | -$5.92K |
|
|
CHMI
2633
Cherry Hill Mortgage Investment Corp
CHMI
$108M
| $369K | ﹤0.01% |
135,260
-29,326
| -18% | -$85.5K |
|
2634
STAG Industrial
STAG
$7.14B
| $368K | ﹤0.01% |
10,155
-36,700
| -78% | -$1.27M |
|
2635
Motorcar Parts of America
MPAA
$219M
| $368K | ﹤0.01% |
32,813
-1,239
| -4% | -$12.4K |
|
2636
Comtech Telecommunications
CMTL
$53M
| $367K | ﹤0.01% |
149,741
-50,315
| -25% | -$90.6K |
|
2637
LGI Homes
LGIH
$1.35B
| $367K | ﹤0.01% |
7,120
-32,259
| -82% | -$1.76M |
|
|
DFTX
2638
Definium Therapeutics
DFTX
$5.81B
| $367K | ﹤0.01% |
56,478
-2,744
| -5% | -$18K |
|
2639
Fulton Financial
FULT
$4.5B
| $366K | ﹤0.01% |
+20,313
| New | +$347K |
|
2640
Zurn Elkay Water Solutions
ZWS
$8.1B
| $366K | ﹤0.01% |
10,016
-15,298
| -60% | -$527K |
|
2641
Natural Gas Services Group
NGS
$448M
| $366K | ﹤0.01% |
14,175
-19
| -0.1% | -$427 |
|
2642
Silicom
SILC
$240M
| $365K | ﹤0.01% |
23,625
-1,296
| -5% | -$18.9K |
|
2643
CI&T Inc
CINT
$474M
| $365K | ﹤0.01% |
61,112
+39,139
| +178% | +$225K |
|
|
ORKA
2644
Oruka Therapeutics
ORKA
$6.78B
| $363K | ﹤0.01% |
32,342
+10,511
| +48% | +$110K |
|
|
MESO
2645
Mesoblast
MESO
$2.16B
| $362K | ﹤0.01% |
+33,213
| New | +$372K |
|
2646
Merchants Bancorp
MBIN
$2.48B
| $361K | ﹤0.01% |
+10,920
| New | +$353K |
|
|
FSCS
2647
First Trust SMID Capital Strength ETF
FSCS
$61.1M
| $361K | ﹤0.01% |
+10,100
| New | +$350K |
|
|
GB
2648
DELISTED
Global Blue Group Holding
GB
| $361K | ﹤0.01% |
48,281
+7,188
| +17% | +$53.3K |
|
2649
CytomX Therapeutics
CTMX
$717M
| $358K | ﹤0.01% |
157,681
+41,206
| +35% | +$66.4K |
|
|
DRD
2650
DRDGold
DRD
$2.68B
| $356K | ﹤0.01% |
+26,700
| New | +$395K |
|
Similar funds
John Overdeck's Q2 2025 Portfolio in Review
As of Q2 2025, John Overdeck held 3,681 positions worth $56.5B, up 21% from $46.8B the previous quarter. Its ten largest holdings account for 7.7% of the portfolio.
John Overdeck deployed $2.96B of net new capital in Q2 2025, opening 509 new positions and adding to 1,200 existing holdings. Its largest new stake was iShares Expanded Tech-Software Sector ETF: 3,154,300 shares worth $345M.
By sector, the portfolio is most concentrated in Technology at 17% of assets, down from 18% a quarter earlier, followed by Financials and Healthcare.
On the sell side, the largest reduction was Broadcom, an estimated $338M trimmed.
- John Overdeck's largest Q2 2025 buy was iShares Expanded Tech-Software Sector ETF: 3,154,300 shares worth $345M.
- John Overdeck added most to UnitedHealth in Q2 2025, an estimated $286M increase.
- John Overdeck's biggest Q2 2025 reduction was Broadcom, cutting an estimated $338M.
- John Overdeck fully exited State Street Utilities Select Sector SPDR ETF in Q2 2025, selling an estimated $134M.
- John Overdeck's ten largest holdings make up 7.7% of its $56.5B portfolio in Q2 2025.
- John Overdeck opened 509 new positions and closed 531 in Q2 2025.
- John Overdeck's portfolio value rose 21% quarter-over-quarter to $56.5B.
Based on Two Sigma Investments's 13F filing for Q2 2025, filed 14 Aug 2025.