John Overdeck Two Sigma Investments
John Overdeck is a co-founder of Two Sigma Investments, one of the world’s leading quantitative and technology-driven investment firms. Two Sigma applies data science, machine learning, and large-scale computing to markets across asset classes. Overdeck’s firm is a central reference point in discussions of modern systematic investing.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$510M |
| 2 |
Broadcom
AVGO
|
+$318M |
| 3 |
Marvell Technology
MRVL
|
+$290M |
| 4 |
Salesforce
CRM
|
+$263M |
| 5 |
Advanced Micro Devices
AMD
|
+$250M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Eli Lilly
LLY
|
+$255M |
| 2 |
Progressive
PGR
|
+$244M |
| 3 |
Visa
V
|
+$238M |
| 4 |
Lam Research
LRCX
|
+$201M |
| 5 |
Elevance Health
ELV
|
+$190M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 17.88% |
| 2 | Healthcare | 13.28% |
| 3 | Financials | 10.32% |
| 4 | Industrials | 9.79% |
| 5 | Consumer Discretionary | 8.58% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
2501
Ichor Holdings
ICHR
$2.13B
| $445K | ﹤0.01% |
19,688
-86,795
| -82% | -$2.56M |
|
2502
Torrid Holdings
CURV
$212M
| $445K | ﹤0.01% |
81,121
-23,451
| -22% | -$140K |
|
2503
Conduent
CNDT
$255M
| $444K | ﹤0.01% |
164,431
-213,415
| -56% | -$780K |
|
2504
SITE Centers
SITC
$159M
| $443K | ﹤0.01% |
34,527
-249,311
| -88% | -$3.55M |
|
2505
ICL Group
ICL
$7.28B
| $443K | ﹤0.01% |
77,900
| – | – |
|
2506
Vuzix
VUZI
$232M
| $443K | ﹤0.01% |
217,067
+105,196
| +94% | +$345K |
|
2507
Southern Company
SO
$104B
| $441K | ﹤0.01% |
4,800
-10,800
| -69% | -$935K |
|
|
EPIX
2508
DELISTED
ESSA Pharma
EPIX
| $441K | ﹤0.01% |
279,120
+67,916
| +32% | +$115K |
|
2509
Cohu
COHU
$2.39B
| $440K | ﹤0.01% |
29,945
-24,593
| -45% | -$512K |
|
2510
BancFirst
BANF
$3.74B
| $438K | ﹤0.01% |
3,984
-1
| -0% | -$116 |
|
2511
Douglas Elliman
DOUG
$178M
| $436K | ﹤0.01% |
253,542
-8,481
| -3% | -$15.3K |
|
|
SEPN
2512
Septerna Inc
SEPN
$1.94B
| $433K | ﹤0.01% |
+74,841
| New | +$854K |
|
2513
Standex International
SXI
$3.67B
| $433K | ﹤0.01% |
2,684
+139
| +5% | +$25.5K |
|
2514
Replimune Group
REPL
$1.48B
| $433K | ﹤0.01% |
44,403
-168,183
| -79% | -$2.08M |
|
2515
Fulcrum Therapeutics
FULC
$294M
| $433K | ﹤0.01% |
150,274
-19,268
| -11% | -$70.8K |
|
2516
Enanta Pharmaceuticals
ENTA
$414M
| $430K | ﹤0.01% |
77,890
+13,607
| +21% | +$84K |
|
2517
Oric Pharmaceuticals
ORIC
$1.43B
| $430K | ﹤0.01% |
76,990
-62,693
| -45% | -$548K |
|
2518
CALL
iShares 20+ Year Treasury Bond ETF
TLT
$47B
| $428K | ﹤0.01% |
4,700
-211,400
| -98% | -$18.8M |
|
|
2519
PUT
iShares 20+ Year Treasury Bond ETF
TLT
$47B
| $428K | ﹤0.01% |
4,700
-224,200
| -98% | -$20M |
|
2520
Teledyne Technologies
TDY
$29.1B
| $427K | ﹤0.01% |
857
+235
| +38% | +$116K |
|
2521
RBB Bancorp
RBB
$447M
| $426K | ﹤0.01% |
25,837
+13,254
| +105% | +$241K |
|
|
CWBC
2522
Community West Bancshares
CWBC
$703M
| $426K | ﹤0.01% |
23,066
-9,381
| -29% | -$176K |
|
2523
OptimizeRx
OPRX
$148M
| $425K | ﹤0.01% |
+49,036
| New | +$300K |
|
2524
Sensus Healthcare
SRTS
$56.3M
| $424K | ﹤0.01% |
89,598
-925
| -1% | -$5.38K |
|
|
CEPU
2525
Central Puerto
CEPU
$2.04B
| $423K | ﹤0.01% |
38,164
-11,429
| -23% | -$151K |
|
Similar funds
John Overdeck's Q1 2025 Portfolio in Review
As of Q1 2025, John Overdeck held 3,617 positions worth $46.8B, up 2% from $45.9B the previous quarter. Its ten largest holdings account for 8.1% of the portfolio.
John Overdeck deployed $2.08B of net new capital in Q1 2025, opening 458 new positions and adding to 1,225 existing holdings. Its largest new stake was Advanced Micro Devices: 2,246,952 shares worth $231M.
By sector, the portfolio is most concentrated in Technology at 18% of assets, up from 16% a quarter earlier, followed by Healthcare and Financials.
On the sell side, the largest reduction was Eli Lilly, an estimated $255M trimmed.
- John Overdeck's largest Q1 2025 buy was Advanced Micro Devices: 2,246,952 shares worth $231M.
- John Overdeck added most to State Street SPDR S&P 500 ETF Trust in Q1 2025, an estimated $510M increase.
- John Overdeck's biggest Q1 2025 reduction was Eli Lilly, cutting an estimated $255M.
- John Overdeck fully exited Coinbase in Q1 2025, selling an estimated $45M.
- John Overdeck's ten largest holdings make up 8.1% of its $46.8B portfolio in Q1 2025.
- John Overdeck opened 458 new positions and closed 452 in Q1 2025.
- John Overdeck's portfolio value rose 2% quarter-over-quarter to $46.8B.
Based on Two Sigma Investments's 13F filing for Q1 2025, filed 15 May 2025.