John Overdeck Two Sigma Investments
John Overdeck is a co-founder of Two Sigma Investments, one of the world’s leading quantitative and technology-driven investment firms. Two Sigma applies data science, machine learning, and large-scale computing to markets across asset classes. Overdeck’s firm is a central reference point in discussions of modern systematic investing.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$510M |
| 2 |
Broadcom
AVGO
|
+$318M |
| 3 |
Marvell Technology
MRVL
|
+$290M |
| 4 |
Salesforce
CRM
|
+$263M |
| 5 |
Advanced Micro Devices
AMD
|
+$250M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Eli Lilly
LLY
|
+$255M |
| 2 |
Progressive
PGR
|
+$244M |
| 3 |
Visa
V
|
+$238M |
| 4 |
Lam Research
LRCX
|
+$201M |
| 5 |
Elevance Health
ELV
|
+$190M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 17.88% |
| 2 | Healthcare | 13.28% |
| 3 | Financials | 10.32% |
| 4 | Industrials | 9.79% |
| 5 | Consumer Discretionary | 8.58% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
|
APLT
2476
DELISTED
Applied Therapeutics
APLT
| $470K | ﹤0.01% |
960,587
+666,777
| +227% | +$393K |
|
2477
Lindsay Corp
LNN
$1.17B
| $468K | ﹤0.01% |
3,700
+390
| +12% | +$50.9K |
|
2478
AN2 Therapeutics
ANTX
$213M
| $468K | ﹤0.01% |
343,960
-56,372
| -14% | -$71K |
|
2479
Lamar Advertising Co
LAMR
$15.4B
| $468K | ﹤0.01% |
+4,109
| New | +$500K |
|
2480
LSB Industries
LXU
$745M
| $467K | ﹤0.01% |
70,909
-31,759
| -31% | -$248K |
|
2481
IQ Candriam US Large Cap Equity ETF
IQSU
$325M
| $467K | ﹤0.01% |
10,300
-4,600
| -31% | -$221K |
|
2482
MetroCity Bankshares
MCBS
$1.01B
| $466K | ﹤0.01% |
16,903
+6,498
| +62% | +$195K |
|
|
EA
2483
DELISTED
Electronic Arts
EA
| $466K | ﹤0.01% |
+3,224
| New | +$435K |
|
2484
HBT Financial
HBT
$1.3B
| $466K | ﹤0.01% |
20,781
-10,286
| -33% | -$242K |
|
|
AMWD
2485
DELISTED
American Woodmark
AMWD
| $465K | ﹤0.01% |
7,910
+2,719
| +52% | +$192K |
|
|
INVX
2486
Innovex International
INVX
$2.01B
| $465K | ﹤0.01% |
25,879
-26,023
| -50% | -$442K |
|
2487
Nordson
NDSN
$18.7B
| $462K | ﹤0.01% |
+2,288
| New | +$484K |
|
|
RAPT
2488
DELISTED
RAPT Therapeutics
RAPT
| $456K | ﹤0.01% |
46,751
+24,193
| +107% | +$238K |
|
2489
State Street SPDR S&P Dividend ETF
SDY
$22.1B
| $456K | ﹤0.01% |
+3,359
| New | +$452K |
|
2490
Pediatrix Medical
MD
$2.19B
| $454K | ﹤0.01% |
31,328
-54,615
| -64% | -$776K |
|
|
ACLX
2491
DELISTED
Arcellx
ACLX
| $453K | ﹤0.01% |
6,900
| – | – |
|
|
ASRT
2492
DELISTED
Assertio
ASRT
| $452K | ﹤0.01% |
44,631
-16,039
| -26% | -$191K |
|
2493
First Bancorp
FBNC
$2.64B
| $450K | ﹤0.01% |
11,220
| – | – |
|
2494
Hyatt Hotels
H
$16.7B
| $450K | ﹤0.01% |
+3,673
| New | +$529K |
|
2495
Gevo
GEVO
$423M
| $450K | ﹤0.01% |
387,800
+57,872
| +18% | +$96.9K |
|
2496
Simplify Health Care ETF
PINK
$385M
| $448K | ﹤0.01% |
+15,300
| New | +$459K |
|
2497
Gaotu Techedu
GOTU
$410M
| $448K | ﹤0.01% |
+137,813
| New | +$381K |
|
2498
FreightCar America
RAIL
$238M
| $448K | ﹤0.01% |
80,965
+52,667
| +186% | +$500K |
|
2499
Bank First Corp
BFC
$1.7B
| $447K | ﹤0.01% |
4,442
+451
| +11% | +$45.7K |
|
2500
Cabaletta Bio
CABA
$544M
| $445K | ﹤0.01% |
321,411
-430,483
| -57% | -$917K |
|
Similar funds
John Overdeck's Q1 2025 Portfolio in Review
As of Q1 2025, John Overdeck held 3,617 positions worth $46.8B, up 2% from $45.9B the previous quarter. Its ten largest holdings account for 8.1% of the portfolio.
John Overdeck deployed $2.08B of net new capital in Q1 2025, opening 458 new positions and adding to 1,225 existing holdings. Its largest new stake was Advanced Micro Devices: 2,246,952 shares worth $231M.
By sector, the portfolio is most concentrated in Technology at 18% of assets, up from 16% a quarter earlier, followed by Healthcare and Financials.
On the sell side, the largest reduction was Eli Lilly, an estimated $255M trimmed.
- John Overdeck's largest Q1 2025 buy was Advanced Micro Devices: 2,246,952 shares worth $231M.
- John Overdeck added most to State Street SPDR S&P 500 ETF Trust in Q1 2025, an estimated $510M increase.
- John Overdeck's biggest Q1 2025 reduction was Eli Lilly, cutting an estimated $255M.
- John Overdeck fully exited Coinbase in Q1 2025, selling an estimated $45M.
- John Overdeck's ten largest holdings make up 8.1% of its $46.8B portfolio in Q1 2025.
- John Overdeck opened 458 new positions and closed 452 in Q1 2025.
- John Overdeck's portfolio value rose 2% quarter-over-quarter to $46.8B.
Based on Two Sigma Investments's 13F filing for Q1 2025, filed 15 May 2025.