IC

Ikarian Capital Portfolio holdings

AUM $302M
This Quarter Return
+17.81%
1 Year Return
+65.21%
3 Year Return
+441.33%
5 Year Return
+548.26%
10 Year Return
–
AUM
$200M
AUM Growth
+$200M
Cap. Flow
-$68M
Cap. Flow %
-33.93%
Top 10 Hldgs %
50.04%
Holding
142
New
18
Increased
7
Reduced
40
Closed
52

Top Buys

1
ISEE
IVERIC bio, Inc. Common Stock
ISEE
$16.7M
2
RXDX
Prometheus Biosciences, Inc. Common Stock
RXDX
$13.6M
3
DCPH
Deciphera Pharmaceuticals, Inc. Common Stock
DCPH
$9.11M
4
SAGE
Sage Therapeutics
SAGE
$6.18M
5
ACAD icon
Acadia Pharmaceuticals
ACAD
$5.32M

Top Sells

1
KRTX
Karuna Therapeutics, Inc. Common Stock
KRTX
$12.7M
2
ALNY icon
Alnylam Pharmaceuticals
ALNY
$11.7M
3
VRTX icon
Vertex Pharmaceuticals
VRTX
$11.3M
4
UTHR icon
United Therapeutics
UTHR
$9.43M
5
CLDX icon
Celldex Therapeutics
CLDX
$6.2M

Sector Composition

1 Healthcare 98.33%
2 Consumer Staples 0%
3 Technology 0%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
VRDN icon
101
Viridian Therapeutics
VRDN
$1.5B
– –
0
– –
VRTX icon
102
Vertex Pharmaceuticals
VRTX
$100B
– –
-40,000
Closed -$11.3M
VSTM icon
103
Verastem
VSTM
$569M
– –
-228,023
Closed -$265K
WVE icon
104
Wave Life Sciences
WVE
$1.53B
– –
-98,039
Closed -$318K
XBI icon
105
SPDR S&P Biotech ETF
XBI
$5.07B
– –
0
– –
ZLAB icon
106
Zai Lab
ZLAB
$3.68B
– –
-81,843
Closed -$278K
TNFA
107
TNF Pharmaceuticals, Inc. Common Stock
TNFA
$685K
– –
-81,089
Closed -$176K
RNTX
108
Rein Therapeutics, Inc. Common Stock
RNTX
$32M
– –
-2,892,316
Closed -$752K
WHWK
109
Whitehawk Therapeutics, Inc. Common Stock
WHWK
$84.8M
– –
-412,343
Closed -$1.27M
CMRX
110
DELISTED
Chimerix, Inc.
CMRX
– –
-441,203
Closed -$917K
NTBL
111
DELISTED
Notable Labs, Ltd. Ordinary Shares
NTBL
– –
-830,007
Closed -$1.34M
KA
112
DELISTED
Kineta, Inc. Common Stock
KA
– –
-104,392
Closed -$190K
KRTX
113
DELISTED
Karuna Therapeutics, Inc. Common Stock
KRTX
– –
-100,000
Closed -$12.7M
TCDA
114
DELISTED
Tricida, Inc. Common Stock
TCDA
– –
0
– –
AYLA
115
DELISTED
Ayala Pharmaceuticals, Inc. Common Stock
AYLA
– –
-697,316
Closed -$759K
OTIC
116
DELISTED
Otonomy, Inc.
OTIC
– –
-180
Closed –
BXRX
117
DELISTED
Baudax Bio, Inc. Common Stock
BXRX
– –
-2,966
Closed -$3K
CFRX
118
DELISTED
ContraFect Corporation
CFRX
– –
0
– –
INBX
119
DELISTED
Inhibrx, Inc. Common Stock
INBX
– –
-49,372
Closed -$561K
EOLS icon
120
Evolus
EOLS
$494M
– –
-45,516
Closed -$529K
FULC icon
121
Fulcrum Therapeutics
FULC
$351M
– –
0
– –
GERN icon
122
Geron
GERN
$893M
– –
0
– –
GLPG icon
123
Galapagos
GLPG
$2.07B
– –
-86,865
Closed -$4.83M
HEPA
124
DELISTED
Hepion Pharmaceuticals
HEPA
– –
-410,189
Closed -$235K
HRMY icon
125
Harmony Biosciences
HRMY
$2.12B
– –
-86,035
Closed -$4.2M
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5
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