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GPP

Great Point Partners Portfolio holdings

AUM $529M
1-Year Est. Return 337.4%
This Fund
S&P 500
This Quarter Est. Return
-12.75%
1 Year Est. Return
+337.4%
3 Year Est. Return
+710.06%
5 Year Est. Return
+1,177.67%
10 Year Est. Return
+20,064.24%
AUM
$189M
AUM Growth
-$23.4M
Cap. Flow
+$22.5M
Cap. Flow %
11.91%
Top 10 Hldgs %
53.8%
Holding
36
New
10
Increased
6
Reduced
8
Closed
4

Top Buys

Rank Stock Value
1
AKBA icon
Akebia Therapeutics
AKBA
+$10.2M
2
PCVX icon
Vaxcyte
PCVX
+$9.24M
3
IMVT icon
Immunovant
IMVT
+$7.84M
4
ASND icon
Ascendis Pharma A/S
ASND
+$7.14M
5
AMLX icon
Amylyx Pharmaceuticals
AMLX
+$6.45M

Top Sells

Rank Stock Value
1
IONS icon
Ionis Pharmaceuticals
IONS
+$8.35M
2
KALV
KalVista Pharmaceuticals
KALV
+$7.89M
3
JSPR icon
Jasper Therapeutics
JSPR
+$6.89M
4
ORKA
Oruka Therapeutics
ORKA
+$4.44M
5
DVAX
Dynavax Technologies
DVAX
+$3.49M

Sector Composition

Rank Sector Weight
1 Healthcare 97.45%
2 Miscellaneous 2.55%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
CNTX icon
26
Context Therapeutics
CNTX
$33.5M
$2.87M 1.52%
4,683,711
– –
RZLT icon
27
Rezolute
RZLT
$400M
$2.42M 1.28%
833,042
+211,148
+34% +$920K
CNTA
28
DELISTED
Centessa Pharmaceuticals
CNTA
$2.15M 1.14%
+149,702
New +$2.45M
VYGR icon
29
Voyager Therapeutics
VYGR
$190M
$2.12M 1.12%
626,275
-200,476
-24% -$936K
PMN icon
30
ProMIS Neurosciences
PMN
$116M
$1.84M 0.97%
105,805
– –
UPB
31
Upstream Bio Inc
UPB
$300M
$1.84M 0.97%
300,000
– –
PLRX icon
32
Pliant Therapeutics
PLRX
$69.4M
$1.15M 0.61%
850,000
-205,000
-19% -$1.24M
JSPR icon
33
Jasper Therapeutics
JSPR
$19M
– –
-322,380
Closed -$6.89M
OPTN
34
DELISTED
OptiNose
OPTN
– –
-370,269
Closed -$2.47M
URGN icon
35
UroGen Pharma
URGN
$2.04B
– –
-187,843
Closed -$2M
ORKA
36
Oruka Therapeutics
ORKA
$6.1B
– –
-228,803
Closed -$4.44M
1
2

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Great Point Partners's Q1 2025 Portfolio in Review

As of Q1 2025, Great Point Partners held 36 positions worth $189M, down 11% from $212M the previous quarter. Its ten largest holdings account for 54% of the portfolio.

Great Point Partners deployed $22.5M of net new capital in Q1 2025, opening 10 new positions and adding to 6 existing holdings. Its largest new stake was Akebia Therapeutics: 4,973,840 shares worth $9.55M.

By sector, the portfolio is most concentrated in Healthcare at 97% of assets, down from 100% a quarter earlier, followed by Miscellaneous.

On the sell side, the largest reduction was Ionis Pharmaceuticals, an estimated $8.35M trimmed.

  • Great Point Partners's largest Q1 2025 buy was Akebia Therapeutics: 4,973,840 shares worth $9.55M.
  • Great Point Partners added most to Merus in Q1 2025, an estimated $3.45M increase.
  • Great Point Partners's biggest Q1 2025 reduction was Ionis Pharmaceuticals, cutting an estimated $8.35M.
  • Great Point Partners fully exited Jasper Therapeutics in Q1 2025, selling an estimated $6.89M.
  • Great Point Partners's ten largest holdings make up 54% of its $189M portfolio in Q1 2025.
  • Great Point Partners opened 10 new positions and closed 4 in Q1 2025.
  • Great Point Partners's portfolio value fell 11% quarter-over-quarter to $189M.

Based on Great Point Partners's 13F filing for Q1 2025, filed 15 May 2025.