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EHI

Eagle Health Investments Portfolio holdings

AUM $603M
1-Year Est. Return 111.06%
This Fund
S&P 500
This Quarter Est. Return
+41.7%
1 Year Est. Return
+111.06%
3 Year Est. Return
+240.87%
5 Year Est. Return
+290.92%
10 Year Est. Return
–
AUM
$455M
AUM Growth
+$74.1M
Cap. Flow
-$12.9M
Cap. Flow %
-2.84%
Top 10 Hldgs %
70.66%
Holding
34
New
11
Increased
3
Reduced
5
Closed
4

Top Buys

Rank Stock Value
1
LEGN icon
Legend Biotech
LEGN
+$11.7M
2
ICLR icon
Icon
ICLR
+$11.5M
3
KYMR icon
Kymera Therapeutics
KYMR
+$9.2M
4
ATAI icon
AtaiBeckley Inc
ATAI
+$7.92M
5
QURE icon
uniQure
QURE
+$7.92M

Top Sells

Rank Stock Value
1
RARE icon
Ultragenyx Pharmaceutical
RARE
+$21M
2
ARGX icon
argenx
ARGX
+$12.6M
3
INSM icon
Insmed
INSM
+$11.1M
4
ALNY icon
Alnylam Pharmaceuticals
ALNY
+$10.8M
5
AKRO
Akero Therapeutics
AKRO
+$10.7M

Sector Composition

Rank Sector Weight
1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
MLTX icon
26
MoonLake Immunotherapeutics
MLTX
$1.41B
$2.47M 0.54%
+187,600
New +$2.21M
ALKS icon
27
Alkermes
ALKS
$8.26B
$2.29M 0.5%
81,800
– –
IRON icon
28
Disc Medicine
IRON
$3.12B
$2.15M 0.47%
+27,100
New +$2.29M
IMCR icon
29
Immunocore
IMCR
$1.74B
$1.61M 0.35%
46,300
– –
VIR icon
30
Vir Biotechnology
VIR
$1.51B
$1.45M 0.32%
240,500
– –
AGIO icon
31
Agios Pharmaceuticals
AGIO
$1.95B
– –
-246,230
Closed -$9.88M
AKRO
32
DELISTED
Akero Therapeutics
AKRO
– –
-226,400
Closed -$10.7M
ALNY icon
33
Alnylam Pharmaceuticals
ALNY
$29.6B
– –
-23,686
Closed -$10.8M
RARE icon
34
Ultragenyx Pharmaceutical
RARE
$2.66B
– –
-697,000
Closed -$21M
1
2

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Eagle Health Investments's Q4 2025 Portfolio in Review

As of Q4 2025, Eagle Health Investments held 34 positions worth $455M, up 19% from $381M the previous quarter. Its ten largest holdings account for 71% of the portfolio.

Eagle Health Investments's Q4 2025 filing shows 11 new, 3 increased, 5 reduced and 4 closed positions. Its largest new stake was Legend Biotech: 408,652 shares worth $8.88M. The largest sale was Ultragenyx Pharmaceutical, an estimated $21M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, unchanged from a quarter earlier.

  • Eagle Health Investments's largest Q4 2025 buy was Legend Biotech: 408,652 shares worth $8.88M.
  • Eagle Health Investments added most to Icon in Q4 2025, an estimated $11.5M increase.
  • Eagle Health Investments's biggest Q4 2025 reduction was argenx, cutting an estimated $12.6M.
  • Eagle Health Investments fully exited Ultragenyx Pharmaceutical in Q4 2025, selling an estimated $21M.
  • Eagle Health Investments's ten largest holdings make up 71% of its $455M portfolio in Q4 2025.
  • Eagle Health Investments opened 11 new positions and closed 4 in Q4 2025.
  • Eagle Health Investments's portfolio value rose 19% quarter-over-quarter to $455M.

Based on Eagle Health Investments's 13F filing for Q4 2025, filed 6 Feb 2026.